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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：298/1  |  提交时间：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载：200/1  |  提交时间：2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
作者:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载：328/1  |  提交时间：2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
作者:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  收藏  |  浏览/下载：189/1  |  提交时间：2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
浏览  |  Adobe PDF(5670Kb)  |  收藏  |  浏览/下载：1/1  |  提交时间：2024/07/17
Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Sesquiterpenoids from the Resina Commiphora Promoting the Apoptotic Activity of PC-3 Prostate Cancer Cells 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
作者:  Dong,Lu;  Li,Yanpeng;  Qin,Fuying;  Cheng,Yongxian
浏览  |  Adobe PDF(1864Kb)  |  收藏  |  浏览/下载：8/1  |  提交时间：2024/07/10
Resina Commiphora  germacrane sesquiterpenes  cell viability  apoptosis  PC-3 cells  ANTIOXIDANT  MYRRHA  BERRYI  MUKUL  
Artemeriopolides A-D, two types of sesquiterpenoid dimers with rare carbon skeletons from Artemisia eriopoda and their antihepatoma cytotoxicity 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 11, 页码: 2635-2641
作者:  He,Xiao-Feng;  Li,Qi-Hao;  Li,Tian-Ze;  Ma,Yun-Bao;  Dong,Wei;  Yang,Ke-Xin;  Geng,Chang-An;  Zhang,Hao-Wei;  Wang,Yuan;  Chen,Ji-Jun
浏览  |  Adobe PDF(1676Kb)  |  收藏  |  浏览/下载：3/1  |  提交时间：2024/07/22
Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα 期刊论文
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2023, 卷号: 21, 期号: 5, 页码: 1274-1288
作者:  Shen,Chuanbin;  Mackeigan,Daniel T.;  Shoara,Aron A.;  Xu,Runjia;  Bhoria,Preeti;  Karakas,Danielle;  Ma,Wenjing;  Cerenzia,Eric;  Chen,ZiYan;  Hoard,Brock;  Lin,Lisha;  Lei,Xi;  Zhu,Guangheng;  Chen,Pingguo;  Johnson,Philip E.;  Ni,Heyu
浏览  |  Adobe PDF(4055Kb)  |  收藏  |  浏览/下载：2/1  |  提交时间：2024/07/22
fucoidan  glycoprotein Ib  platelet  thrombosis  von Willebrand factor  VON-WILLEBRAND-FACTOR  PLATELET GLYCOPROTEIN IB  MOLECULAR-WEIGHT FUCOIDAN  ARTERIAL THROMBOSIS  IX  AGGREGATION  RECEPTOR  ACTIVATION  FIBRINOGEN  INTEGRIN  
Deciphering complex reticulate evolution of Asian Buddleja (Scrophulariaceae): insights into the taxonomy and speciation of polyploid taxa in the Sino-Himalayan region 期刊论文
ANNALS OF BOTANY, 2023
作者:  Yang,Fengmao;  Ge,Jia;  Guo,Yongjie;  Olmstead,Richard;  Sun,Weibang
浏览  |  Adobe PDF(2981Kb)  |  收藏  |  浏览/下载：35/4  |  提交时间：2024/05/09
Buddleja  phylogenomics  reticulate evolution  polyploidy  plastid genome  low-copy nuclear gene  HYBRIDIZATION  ALIGNMENT  DIVERSIFICATION  ALLOPOLYPLOIDY  PHYLOGENETICS  FRAMEWORK  NUCLEAR  ROBUST  FLOW  
Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis 期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
作者:  Li,Sujuan;  Wang,Weili;  Lin,Lisha;  Yang,Lian;  Cai,Ying;  Yang,Xingzhi;  Zhang,Taocui;  Xiao,Chuang;  Yan,Hui;  Gao,Na;  Zhao,Jinhua
浏览  |  Adobe PDF(2610Kb)  |  收藏  |  浏览/下载：33/5  |  提交时间：2024/05/09
oligosaccharide  platelet activation  receptor  protease-activated  thrombin thrombosis  ANTIPLATELET THERAPIES  ALLOSTERIC LINKAGE  TISSUE FACTOR  PROTEASE  VORAPAXAR  MECHANISM  REVEALS  SITE