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Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
作者:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
浏览  |  Adobe PDF(6313Kb)  |  收藏  |  浏览/下载：68/26  |  提交时间：2022/04/02
Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
浏览  |  Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：112/51  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2388Kb)  |  收藏  |  浏览/下载：46/6  |  提交时间：2022/04/02
Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
Aqueous extract of clove inhibits tumor growth by inducing autophagy through AMPK/ULK pathway 期刊论文
PHYTOTHERAPY RESEARCH, 2019, 卷号: 33, 期号: 7, 页码: 1794-1804
作者:  Li, Cong;  Xu, Huanli;  Chen, Xiaoliang;  Chen, Jijun;  Li, Xiao;  Qiao, Gan;  Tian, Ye;  Yuan, Ru;  Su, Shuonan;  Liu, Xiaohui;  Lin, Xiukun
浏览  |  Adobe PDF(1218Kb)  |  收藏  |  浏览/下载：157/41  |  提交时间：2019/09/10
AMPK  anticancer  aqueous extract of clove  autophagy  traditional Chinese medicine  
Dereplication-guided isolation of a new indole alkaloid triglycoside from the hooks of Uncaria rhynchophylla by LC with ion trap time-of-flight MS 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2018, 卷号: 41, 期号: 7, 页码: 1532-1538
作者:  Zhang, Jian-Gang;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(1155Kb)  |  收藏  |  浏览/下载：200/55  |  提交时间：2018/05/08
5-hydroxytryptamine Receptors  Dereplication-guided Isolation  Indole Alkaloid Triglycoside  Melatonin Receptors  Traditional Chinese Medicine  
The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats 期刊论文
HORMONES AND BEHAVIOR, 2015, 卷号: 69, 期号: 1, 页码: 106-115
作者:  Yu,Dafu;  Zhou,Heng;  Yang,Yuan;  Jiang,Yong;  Wang,Tianchao;  Lv,Liang;  Zhou,Qixin;  Yang,Yuexiong;  Dong,Xuexian;  He,Jianfeng;  Huang,Xiaoyan;  Chen,Jijun;  Wu,Kunhua;  Xu,Lin;  Mao,Rongrong;  Xu,L (reprint author),Chinese Acad Sci,Kunming Inst Zool,Lab Learning & Memory,Kunming 650223,Yunnan,Peoples R China.;  lxu@vip.163.com;  talktomaomao@163.com
浏览  |  Adobe PDF(867Kb)  |  收藏  |  浏览/下载：403/149  |  提交时间：2015/06/29
Hypothyroidism  Hyperthyroidism  Depression  Anxiety  Brain-derived Neurotrophic Factor  
UFLC/MS-IT-TOF guided isolation of anti-HBV active chlorogenic acid analogues from Artemisia capillaris as a traditional Chinese herb for the treatment of hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 156, 期号: 10, 页码: 147-154
作者:  Zhao, Yong;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Chen, Hao;  Cao, Tuan-Wu;  He, Kang;  Wang, Hao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab PhytoChem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  chenjj@mail.kib.ac.cn
浏览  |  Adobe PDF(605Kb)  |  收藏  |  浏览/下载：294/85  |  提交时间：2015/01/20
Artemisia Capillaris  Uflc/ms-it-tof  Chlorogenic Acid Analogues  Anti-hbv Activity  
Small-Molecule Inhibitors for the Treatment of Hepatitis B Virus Documented in Patents 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 5, 页码: 749-776
作者:  Geng, Chang-An;  Wang, Li-Jun;  Guo, Rui-Hua;  Chen, Ji-Jun
浏览  |  Adobe PDF(616Kb)  |  收藏  |  浏览/下载：354/132  |  提交时间：2013/06/08
Hepatitis b Virus (Hbv)  Small-molecule Inhibitors  Nucleoside Analogs  Non-nucleosides  Natural Products  Synthesized Compounds  Chemical Modification  Patents  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(719Kb)  |  收藏  |  浏览/下载：422/137  |  提交时间：2012/11/30
Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms  
Anti-HBV agents. Part 3: Preliminary structure-activity relationships of tetra-acylalisol A derivatives as potent hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 23, 页码: 6659-6665
作者:  Zhang, Quan;  Jiang, Zhi-Yong;  Luo, Jie;  Ma, Yun-Bao;  Liu, Ji-Feng;  Guo, Rui-Hua;  Zhang, Xue-Mei;  Zhou, Jun;  Niu, Wei;  Du, Fei-Fei;  Li, Li;  Li, Chuan;  Chen, Ji-Jun
Adobe PDF(2076Kb)  |  收藏  |  浏览/下载：483/127  |  提交时间：2012/03/21
Anti-hbv Activity  Protostane-type Triterpene  Alisol a  Derivatives  Chemical Modification