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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：366/41  |  提交时间：2017/12/18
Sauruchinenols A and B, unprecedented monocyclic diterpenes with new carbon skeleton from the aerial parts of Saururus chinensis 期刊论文
FITOTERAPIA, 2017, 卷号: 116, 页码: 116-120
作者:  Gao, Xiu;  He, Juan;  Wu, Xing-De;  Peng, Li-Yan;  Shao, Li-Dong;  Li, Yan;  Cheng, Xiao;  Zhao, Qin-Shi
Adobe PDF(503Kb)  |  收藏  |  浏览/下载：281/37  |  提交时间：2017/04/18
Saururus Chinensis  Saururaceae  Sauruchinenols A-d  Anti-no Production  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：266/68  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Evollionines A - C, Three New Alkaloids Isolated from the Fruits of Evodia rutaecarpa 期刊论文
HELVETICA CHIMICA ACTA, 2014, 卷号: 97, 期号: 11, 页码: 1481-1486
作者:  Li, Yan-Hong;  He, Juan;  Li, Yan;  Wu, Xing-De;  Peng, Li-Yan;  Du, Ru-Nan;  Cheng, Xiao;  Zhao, Qin-Shi;  Li, Rong-Tao;  Zhao,QS (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  rongtaolikm@gmail.com
Adobe PDF(218Kb)  |  收藏  |  浏览/下载：489/156  |  提交时间：2015/01/20
Isolated Major Compounds  Prostate-cancer  In-vitro  Triterpenoids  Proliferation  Glycosides  Apoptosis  Leaf  
Sesquiterpenoids from Tussilago farfara and Their Inhibitory Effects on Nitric Oxide Production 期刊论文
PLANTA MEDICA, 2014, 卷号: 80, 期号: 8-9, 页码: 703-709
作者:  Qin, Zhi-Bin;  Zhang, Jing;  Wu, Xing-De;  He, Juan;  Ding, Lin-Fen;  Peng, Li-Yan;  Li, Xing-Yao;  Li, Yan;  Deng, Liang;  Guo, Ya-Dong;  Zhao, Qin-Shi;  Schoch, CL (reprint author), Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA.;  schoch2@ncbi.nlm.nih.gov
Adobe PDF(166Kb)  |  收藏  |  浏览/下载：255/76  |  提交时间：2014/10/11
Tussilago Farfara  Asteraceae  Sesquiterpenoid  Nitric Oxide Inhibition  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：667/101  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
Adobe PDF(531Kb)  |  收藏  |  浏览/下载：299/62  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum 期刊论文
CHEMISTRY & BIODIVERSITY, 2012, 卷号: 9, 期号: 6, 页码: 1213-1220
作者:  Wang, Kou;  Wang, Yuan-Yuan;  Gao, Xiu;  Chen, Xuan-Qin;  Peng, Li-Yan;  Li, Yan;  Xu, Gang;  Zhao, Qin-Shi
Adobe PDF(252Kb)  |  收藏  |  浏览/下载：232/63  |  提交时间：2014/04/02
Hypericum Androsaemum  Androforin a  Hyperandrone a  Cytotoxic Activity  
Development of novel conformation-constrained cytotoxic derivatives of cheliensisin A by embedment of small heterocycles 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 9, 页码: 4238-4244
作者:  Deng, Xu;  Su, Jia;  Zhao, Yu;  Peng, Li-Yan;  Li, Yan;  Yao, Zhu-Jun;  Zhao, Qin-Shi
Adobe PDF(450Kb)  |  收藏  |  浏览/下载：382/97  |  提交时间：2012/03/16
Cheliensisin a  Derivative  Structure-activity Relationship  Cytotoxicity  Anticancer