Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum | |
Wang, Kou1,2; Wang, Yuan-Yuan1; Gao, Xiu1; Chen, Xuan-Qin1,2; Peng, Li-Yan1; Li, Yan1![]() ![]() ![]() | |
通讯作者 | Xu, G (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China,xugang008@mail.kib.ac.cn ; qinshizhao@mail.kib.ac.cn |
2012-06-01 | |
发表期刊 | CHEMISTRY & BIODIVERSITY
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ISSN | 1612-1872 |
卷号 | 9期号:6页码:1213-1220 |
摘要 | Two new polycyclic polyprenylated acylphloroglucinols (PPAPs), androforin A and hyperandrone A (1 and 2, resp.), together with twelve known compounds, were isolated from the aerial parts of Hypericum androsaemum. Their structures were established by detailed spectral analysis. In the cytotoxic assay, 1,4-O-diferuloylsecoisolariciresinol (3) showed activities comparable with those of cisplatin, and acetyloleanolic acid (4) exhibited moderate inhibitory effects against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cancer cell lines. |
关键词 | Hypericum Androsaemum Androforin a Hyperandrone a Cytotoxic Activity |
学科领域 | Biochemistry & Molecular Biology ; Chemistry |
DOI | 10.1002/cbdv.201100154 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000305282600019 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/17606 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Kou,Wang, Yuan-Yuan,Gao, Xiu,et al. Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum[J]. CHEMISTRY & BIODIVERSITY,2012,9(6):1213-1220. |
APA | Wang, Kou.,Wang, Yuan-Yuan.,Gao, Xiu.,Chen, Xuan-Qin.,Peng, Li-Yan.,...&Zhao, Qin-Shi.(2012).Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum.CHEMISTRY & BIODIVERSITY,9(6),1213-1220. |
MLA | Wang, Kou,et al."Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum".CHEMISTRY & BIODIVERSITY 9.6(2012):1213-1220. |
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