Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum
Wang, Kou1,2; Wang, Yuan-Yuan1; Gao, Xiu1; Chen, Xuan-Qin1,2; Peng, Li-Yan1; Li, Yan1; Xu, Gang1; Zhao, Qin-Shi1
Corresponding AuthorXu, G (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China,xugang008@mail.kib.ac.cn ; qinshizhao@mail.kib.ac.cn
2012-06-01
Source PublicationCHEMISTRY & BIODIVERSITY
ISSN1612-1872
Volume9Issue:6Pages:1213-1220
AbstractTwo new polycyclic polyprenylated acylphloroglucinols (PPAPs), androforin A and hyperandrone A (1 and 2, resp.), together with twelve known compounds, were isolated from the aerial parts of Hypericum androsaemum. Their structures were established by detailed spectral analysis. In the cytotoxic assay, 1,4-O-diferuloylsecoisolariciresinol (3) showed activities comparable with those of cisplatin, and acetyloleanolic acid (4) exhibited moderate inhibitory effects against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cancer cell lines.
KeywordHypericum Androsaemum Androforin a Hyperandrone a Cytotoxic Activity
Subject AreaBiochemistry & Molecular Biology ; Chemistry
DOI10.1002/cbdv.201100154
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000305282600019
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/17606
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Wang, Kou,Wang, Yuan-Yuan,Gao, Xiu,et al. Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum[J]. CHEMISTRY & BIODIVERSITY,2012,9(6):1213-1220.
APA Wang, Kou.,Wang, Yuan-Yuan.,Gao, Xiu.,Chen, Xuan-Qin.,Peng, Li-Yan.,...&Zhao, Qin-Shi.(2012).Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum.CHEMISTRY & BIODIVERSITY,9(6),1213-1220.
MLA Wang, Kou,et al."Polycyclic Polyprenylated Acylphloroglucinols and Cytotoxic Constituents of Hypericum androsaemum".CHEMISTRY & BIODIVERSITY 9.6(2012):1213-1220.
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