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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：308/67  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Polyketides from the endophytic fungus Phomopsis sp sh917 by using the one strain/many compounds strategy 期刊论文
TETRAHEDRON, 2017, 卷号: 73, 期号: 26, 页码: 3577-3584
作者:  Tang, Jian-Wei;  Wang, Wei-Guang;  Li, Ao;  Yan, Bing-Chao;  Chen, Rong;  Li, Xiao-Nian;  Du, Xue;  Sun, Han-Dong;  Pu, Jian-Xin
浏览  |  Adobe PDF(1225Kb)  |  收藏  |  浏览/下载：238/88  |  提交时间：2017/07/31
Endophytic Fungus  Phomopsis Sp.  Osmac Strategy  Polyketides  Antiangiogenic Activity  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：453/206  |  提交时间：2017/02/28
Eriocalyxin B, a Novel Autophagy Inducer, Exerts Anti-tumor Activity Through the Suppression of Akt/mTOR/p70S6K Signaling Pathway In breast Cancer 期刊论文
Biochemical Pharmacology, 2017, 卷号: 142, 页码: 58–70
作者:  Xunian Zhou;  Grace Gar-Lee Yue;  Andrew Man-Lok Chan;   Stephen Kwok-Wing Tsui;  Kwok-Pui Fung;   Handong Sun;  Jianxin Pu;  Clara Bik-San Lau
浏览  |  Adobe PDF(5871Kb)  |  收藏  |  浏览/下载：217/55  |  提交时间：2017/11/20
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：315/33  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer 期刊论文
BREAST CANCER RESEARCH, 2014, 卷号: 16, 期号: 4, 页码: 8220-8224
作者:  O'Leary, Patrick C.;  Terrile, Marta;  Bajor, Malgorzata;  Gaj, Pawel;  Hennessy, Bryan T.;  Mills, Gordon B.;  Zagozdzon, Agnieszka;  O'Connor, Darran P.;  Brennan, Donal J.;  Connor, Kate;  Li, Jane;  Gonzalez-Angulo, Ana Maria;  Sun, Han-Dong;  Pu, Jian-Xin;  Ponten, Fredrik;  Uhlen, Mathias;  Jirstrom, Karin;  Nowis, Dominika A.;  Crown, John P.;  Zagozdzon, Radoslaw;  Gallagher, William M.;  Zagozdzon,R (reprint author),UCD Sch Biomol & Biomed Sci,UCD Conway Inst,Canc Biol & Therapeut Lab,Dublin 4,Ireland.;  radoslaw.zagozdzon@wum.edu.pl;  william.gallagher@ucd.ie
Adobe PDF(2561Kb)  |  收藏  |  浏览/下载：200/63  |  提交时间：2015/01/20
Natural-products  Roots  Secretion  Norsesquiterpenoids  Norbisabolane  Pyrimidine