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Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1837Kb)  |  收藏  |  浏览/下载:205/37  |  提交时间:2019/09/10
Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
作者:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(3731Kb)  |  收藏  |  浏览/下载:214/49  |  提交时间:2019/06/24
Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Chemical and biological comparison of different sections of Uncaria rhynchophylla (Gou-Teng) 期刊论文
EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2017, 卷号: 23, 期号: 1, 页码: 11-21
作者:  Zhang, Jian-Gang;  Geng, Chang-An;  Huang, Xiao-Yan;  Chen, Xing-Long;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(521Kb)  |  收藏  |  浏览/下载:364/70  |  提交时间:2017/06/30
Uncaria Rhynchophylla  Gou Teng  Lc-ms Analysis  Chemical Profiles  Mt1/2 And 5-ht1a/2c Receptors  Indole Alkaloids  
Bioactivity-guided synthesis of tropine derivatives as new agonists for melatonin receptors 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 51, 页码: 45059-45063
作者:  Yin, Xiu-Juan;  Geng, Chang-An;  Huang, Xiao-Yan;  Chen, Hao;  Ma, Yun-Bao;  Chen, Xing-Long;  Sun, Chang-Li;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1380Kb)  |  收藏  |  浏览/下载:275/69  |  提交时间:2016/08/22
Lignans from the Fruits of Melia toosendan and Their Agonistic Activities on Melatonin Receptor MT1 期刊论文
PLANTA MEDICA, 2015, 卷号: 81, 期号: 10, 页码: 847-854
作者:  Wang, Hao;  Geng, Chang-An;  Xu, Hong-Bo;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Yang, Cai-Yan;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(244Kb)  |  收藏  |  浏览/下载:266/95  |  提交时间:2015/12/17
Melia Toosendan  Meliaceae  Lignans  Mt1 Receptor  Agonistic Activity  
Synthesis of erythrocentaurin derivatives as a new class of hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 7, 页码: 1568-1571
作者:  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  chenjj@mail.kib.ac.cn
浏览  |  Adobe PDF(1409Kb)  |  收藏  |  浏览/下载:315/116  |  提交时间:2015/06/29
Erythrocentaurin  Anti-hbv Activity  Structure-activity Relationships  
Design, Synthesis and Biological Evaluation of Caudatin Analogs as Potent Hepatitis B Virus Inhibitors 期刊论文
MEDICINAL CHEMISTRY, 2015, 卷号: 11, 期号: 2, 页码: 165-179
作者:  Wang, Li-Jun;  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.
浏览  |  Adobe PDF(375Kb)  |  收藏  |  浏览/下载:221/75  |  提交时间:2015/06/29
Anti-hbv Activity  Caudatin Analogs  Hepatitis b e Antigen (Hbeag)  Hepatitis b Surface Antigen (Hbsag)  Hbv Dna Replication  Structure-activity Relationships(Sars)  Synthesis  
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载:313/75  |  提交时间:2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Rapid characterization of chemical constituents in Saniculiphyllum guangxiense by ultra fast liquid chromatography with diode array detection and electrospray ionization tandem mass spectrometry 期刊论文
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2014, 卷号: 361, 页码: 9-22
作者:  Geng, Chang-An;  Chen, Hao;  Chen, Xing-Long;  Zhang, Xue-Mei;  Lei, Li-Gong;  Chen, Ji-Jun
Adobe PDF(1986Kb)  |  收藏  |  浏览/下载:760/232  |  提交时间:2014/05/16
Lc-dad/esi-msn  Saniculiphyllum Guangxiense  Cyanogenic Glycosides  Triterpenoids  Phenolic Sulfates  
Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 10, 页码: 3473-3479
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Chen, Hao;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(5043Kb)  |  收藏  |  浏览/下载:407/182  |  提交时间:2012/06/07
Glycyrrhetinic Acid Derivatives  Anti-hbv Activity  Structure-activity Relationships