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Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1889-1906
作者:  Li, Yaping;  Wu, Dong-mei;  Kong, Ling-mei;  Zhang, Shuqun;  Du, Haibo;  Sun, Wei;  Zhang, Li;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载:156/0  |  提交时间:2020/03/26
bioassay  ensemble docking  scoring function  virtual screening  Wee1 inhibitors  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:275/63  |  提交时间:2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(500Kb)  |  收藏  |  浏览/下载:459/201  |  提交时间:2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Synthesis and anti-proliferative activity of allogibberic acid derivatives containing 1,2,3-triazole pharmacophore 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2543-2549
作者:  Wu, Ming-Jiang;  Wu, Dong-Mei;  Chen, Jing-Bo;  Zhao, Jing-Feng;  Gong, Liang;  Gong, Ya-Xiao;  Li, Yan;  Yang, Xiao-Dong;  Zhang, Hongbin
收藏  |  浏览/下载:146/0  |  提交时间:2019/03/29
Synthesis and anti-proliferative activity of allogibberic acid derivatives containing 1,2,3-triazole pharmacophore 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 152, 页码: 105-112
作者:  Wu, Ming-Jiang;  Wu, Dong-Mei;  Chen, Jing-Bo;  Zhao, Jing-Feng;  Gong, Liang;  Gong, Ya-Xiao;  Li, Yan;  Yang, Xiao-Dong;  Zhang, Hongbin
收藏  |  浏览/下载:273/0  |  提交时间:2018/12/27
Synthesis and anticancer activity of dimeric podophyllotoxin derivatives 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2018, 卷号: 12, 页码: 3393-3406
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Yang, Dan;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(916Kb)  |  收藏  |  浏览/下载:447/102  |  提交时间:2018/11/12
Podophyllotoxin  Dimeric Podophyllotoxin Derivatives  Cuaac Reaction  Perbuty-tylated Glucose  Antitumor  Synthesis  
ent-Kaurene diterpenoids from Isodon phyllostachys 期刊论文
TETRAHEDRON LETTERS, 2017, 卷号: 58, 期号: 4, 页码: 349-351
作者:  Yang, Jin;  Wang, Wei-Guang;  Wu, Hai-Yan;  Liu, Miao;  Jiang, Hua-Yi;  Du, Xue;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(532Kb)  |  收藏  |  浏览/下载:447/65  |  提交时间:2017/04/17
Isodon Phyllostachys  Diterpenoid  Ent-kaurene  
Sauruchinenols A and B, unprecedented monocyclic diterpenes with new carbon skeleton from the aerial parts of Saururus chinensis 期刊论文
FITOTERAPIA, 2017, 卷号: 116, 页码: 116-120
作者:  Gao, Xiu;  He, Juan;  Wu, Xing-De;  Peng, Li-Yan;  Shao, Li-Dong;  Li, Yan;  Cheng, Xiao;  Zhao, Qin-Shi
浏览  |  Adobe PDF(503Kb)  |  收藏  |  浏览/下载:343/41  |  提交时间:2017/04/18
Saururus Chinensis  Saururaceae  Sauruchinenols A-d  Anti-no Production  
Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys 期刊论文
SCIENCE CHINA-CHEMISTRY, 2016, 卷号: 59, 期号: 9, 页码: 1211-1215
作者:  Yang, Jin;  An, Yaqi;  Wu, Haiyan;  Liu, Miao;  Wang, Weiguang;  Du, Xue;  Li, Yan;  Pu, Jianxin;  Sun, Handong
Adobe PDF(566Kb)  |  收藏  |  浏览/下载:500/48  |  提交时间:2016/11/04
Isodon Phyllostachys  Diterpenoid  Ent-kaurane  Ent-abietane  
Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum 期刊论文
FITOTERAPIA, 2016, 卷号: 109, 页码: 224-229
作者:  He, Juan;  Peng, Li-Yan;  Tu, Lin;  Wu, Xing-De;  Dong, Liao-Bing;  Pan, Zheng-Hong;  Chen, Xuan-Qin;  Su, Jia;  Zhao, Yu;  Xu, Gang;  Cheng, Xiao;  Li, Yan;  Zhao, Qin-Shi
浏览  |  Adobe PDF(446Kb)  |  收藏  |  浏览/下载:274/90  |  提交时间:2016/08/22
Viburnum Odoratissimum  Vibsane-type Diterpenes  Vibsanols C-h  Vibsanin x  Cytotoxicity