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Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：206/31  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
A unique spiro-beta-triazinedione-gamma-hydantoin type alkaloid with antiviral activity against tobacco mosaic virus from Streptomyces gamaensis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 18, 页码: 3215-3219
作者:  Guo, Xiaowei;  Wang, Jidong;  Su, Can;  Liu, Chongxi;  Ma, Xiao-Yan;  Yu, Zhiyin;  Li, Jiansong;  Wang, Xiangjing;  Xiang, Wensheng;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1243Kb)  |  收藏  |  浏览/下载：241/70  |  提交时间：2019/10/28
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：244/41  |  提交时间：2019/07/29
Enantioselective Total Synthesis of (+)-Flavisiamine F via Late-Stage Visible-Light-Induced Photochemical Cyclization 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 期号: 16, 页码: 5443-5446
作者:  Tong, Xiaogang;  Shi, Bingfei;  Liang, Kangjiang;  Liu, Qian;  Xia, Chengfeng
浏览  |  Adobe PDF(910Kb)  |  收藏  |  浏览/下载：158/44  |  提交时间：2019/07/29
alkaloids  asymmetric catalysis  photochemical cyclization  rearrangement  total synthesis  
Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2019, 卷号: 36, 期号: 4, 页码: 626-665
作者:  Liu, Yan;  Jing, Shu-Xi;  Luo, Shi-Hong;  Li, Sheng-Hong
浏览  |  Adobe PDF(5702Kb)  |  收藏  |  浏览/下载：233/37  |  提交时间：2019/05/24
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(2732Kb)  |  收藏  |  浏览/下载：264/42  |  提交时间：2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS  
Synthesis, structure activity relationship and in vitro anti-influenza virus activity of novel polyphenol-pentacyclic triterpene conjugates 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 560-568
作者:  Li, Haiwei;  Li, Man;  Xu, Renyang;  Wang, Shouxin;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(1830Kb)  |  收藏  |  浏览/下载：218/28  |  提交时间：2019/03/25
Influenza virus  Pentacyclic triterpene  Polyphenol  Entry inhibitor  Hemagglutinin  
Redox Dual-Responsive and O-2-Evolving Theranostic Nanosystem for Highly Selective Chemotherapy against Hypoxic Tumors 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 90-103
作者:  Chen, Huachao;  Li, Fei;  Yao, Yongrong;  Wang, Zhe;  Zhang, Zhihao;  Tan, Ninghua
浏览  |  Adobe PDF(3409Kb)  |  收藏  |  浏览/下载：213/55  |  提交时间：2019/07/29
cancer  theranostic system  hypoxic tumor  ROS/GSH dual-activatable  cyclopeptide RA-V  fluorescence imaging  
Research Progress of Polycyclic Polyprenylated Acylphloroglucinols 期刊论文
CHEMICAL REVIEWS, 2018, 卷号: 118, 期号: 7, 页码: 3508-3558
作者:  Yang, Xing-Wei;  Grossman, Robert B.;  Xu, Gang
浏览  |  Adobe PDF(27097Kb)  |  收藏  |  浏览/下载：551/109  |  提交时间：2018/05/08
Structural analysis and biological activity of a highly regular glycosaminoglycan from Achatina fulica 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 181, 页码: 433-441
作者:  Liu, Jie;  Zhou, Lutan;  He, Zhicheng;  Gao, Na;  Shang, Feineng;  Xu, Jianping;  Li, Zi;  Yang, Zengming;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(2955Kb)  |  收藏  |  浏览/下载：295/66  |  提交时间：2018/05/08
Snail  Glycosaminoglycan  Chemical Structure  Heparin  Anticoagulant