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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
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Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Phylotranscriptomics of Swertiinae (Gentianaceae) reveals that key floral traits are not phylogenetically correlated 期刊论文
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2023, 卷号: 65, 期号: 6, 页码: 1490-1504
作者:  Chen,Chunlin;  Ruhfel,Brad R.;  Li,Jialiang;  Wang,Zefu;  Zhang,Lushui;  Zhang,Lei;  Mao,Xingxing;  Wang,Ji;  He,Dashan;  Luo,Yue;  Hu,Quanjun;  Duan,Yuanwen;  Xu,Xiaoting;  Xi,Zhenxiang;  Liu,Jianquan
浏览  |  Adobe PDF(1712Kb)  |  收藏  |  浏览/下载：23/8  |  提交时间：2024/07/10
ancient hybridization  floral diversity  Gentianaceae  phylogenomics  Qinghai-Tibet Plateau  subtribe Swertiinae  ADAPTIVE RADIATION  SEQUENCE  EVOLUTION  PHYLOGENY  DIVERSIFICATION  GENTIANELLA  GENTIANINAE  NUCLEAR  SPECIATION  INFERENCE  
A comparative full-length transcriptomic resource provides insight into the perennial monocarpic mass flowering 期刊论文
PLANT JOURNAL, 2023, 卷号: 116, 期号: 6, 页码: 1842-1855
作者:  Zhao,Jiu-Xia;  Wang,Shu;  Liu,Jiazhi;  Jiang,Xiao-Dong;  Wen,Jing;  Suo,Zhi-Quan;  Liu,Jie;  Zhong,Mi-Cai;  Wang,Qin;  Gu,Zhirong;  Liu,Changning;  Deng,Yunfei;  Hu,Jin-Yong;  Li,De-Zhu
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perennial monocarpic mass flowering  Strobilanthes  ISO-seq  RNA-seq  BlueOmics  PSEUDO-RESPONSE REGULATORS  STROBILANTHES ACANTHACEAE  EXPRESSION ANALYSIS  GENE  TIME  PROTEIN  LONG  FKF1  PRR5  CLASSIFICATION  
Marsdenia tenacissima genome reveals calcium adaptation and tenacissoside biosynthesis 期刊论文
PLANT JOURNAL, 2023, 卷号: 113, 期号: 6, 页码: 1146-1159
作者:  Zhou,Yanli;  Fan,Wei;  Zhang,Haoyue;  Zhang,Jingling;  Zhang,Guanghui;  Wang,Ding;  Xiang,Guisheng;  Zhao,Changhong;  Li,Lianhua;  He,Simei;  Lu,Yingchun;  Zhao,Jiuxia;  Meng,Zhengui;  Zhang,Xianmin;  Meng,Hengling;  Yin,Xinhua;  Yang,Shengchao;  Long,Guangqiang
浏览  |  Adobe PDF(2474Kb)  |  收藏  |  浏览/下载：18/7  |  提交时间：2024/07/10
genome assembly  Hi-C  Apocynaceae  Ca2+ adaptation  cell-wall remodeling  Marsdenia tenacissima  CELL  GENES  TRANSCRIPTOME  MECHANISMS  ALIGNMENT  SOIL  
Inverse Electron-Demanding Diels-Alder Reactions in the Chemical Synthesis of Prenylated Indole Alkaloids Containing a Bicycle[2.2.2]diazaoctane Moiety: A Theoretical Study 期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2023, 卷号: 18, 期号: 7
作者:  Xu,Wenqiang;  Sun,Tian-Yu;  Di,Yingtong;  Hao,Xiaojiang;  Wu,Yun-Dong
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alkaloids  chemical synthesis  inverse-electron demanding Diels-Alder reaction  reaction mechanisms  theoretical study  BIOMIMETIC TOTAL-SYNTHESIS  CORRELATED MOLECULAR CALCULATIONS  MARINE-DERIVED FUNGUS  GAUSSIAN-BASIS SETS  (-)-VERSICOLAMIDE B  ORBITAL METHODS  BREVIANAMIDE-A  STEPHACIDIN-A  MODEL  CONCISE  
Insights into the mechanisms involved in the fungal degradation of plastics 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 262, 页码: 115202
作者:  Okal,Eyalira Jacob;  Heng,Gui;  Magige,Ephie A.;  Khan,Sehroon;  Wu,Shixi;  Ge,Zhiqiang;  Zhang,Tianfu;  Mortimer,Peter E.;  Xu,Jianchu
浏览  |  Adobe PDF(5735Kb)  |  收藏  |  浏览/下载：19/8  |  提交时间：2024/07/22
Plastic biodegradation  Pre-treatment  Enzyme hydrolysis  Prooxidants  Molecular mechanisms  SURFACE BINDING-PROTEIN  WHITE-ROT FUNGI  MICROBIAL-DEGRADATION  MANGANESE PEROXIDASE  LIGNIN PEROXIDASE  GENE-EXPRESSION  POLYETHYLENE TEREPHTHALATE  TRANSCRIPTIONAL REGULATION  BIOLOGICAL DEGRADATION  ENZYMATIC DEGRADATION  
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(16654Kb)  |  收藏  |  浏览/下载：24/4  |  提交时间：2024/07/22
Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin 期刊论文
MOLECULAR THERAPY, 2023, 卷号: 31, 期号: 10, 页码: 3015-3033
作者:  Hao,Mengjiao;  Guan,Zhuoji;  Zhang,Zhikang;  Ai,Haopeng;  Peng,Xing;  Zhou,Huihao;  Xu,Jun;  Gu,Qiong
浏览  |  Adobe PDF(8787Kb)  |  收藏  |  浏览/下载：27/11  |  提交时间：2024/07/25
INTERMEDIATE-FILAMENT PROTEIN  MECHANISMS  PATHWAYS  ADHESION  IDENTIFICATION  SMAD  
Structurally diverse spirocyclic polycyclic polyprenylated acylphloroglucinols from Hypericum ascyron Linn. and their anti-tumor activity 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 212, 页码: 113727
作者:  Hu,Ya-Li;  Yue,Grace Gar-Lee;  Li,Xing-Ren;  Xu,Gang;  Lau,Clara Bik-San
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Hypericaceae  Polycyclic polyprenylated acylphloroglucinols  Spirocyclic polyprenylated acylphloroglucinols  HCT116 cells  Zebrafish model  Hypericum ascyron Linn  NATURAL-PRODUCTS  A-H  DERIVATIVES  FLOWERS  VEGF  
Genomic convergence underlying high-altitude adaptation in alpine plants 期刊论文
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2023
作者:  Zhang,Xu;  Kuang,Tianhui;  Dong,Wenlin;  Qian,Zhihao;  Zhang,Huajie;  Landis,Jacob B. B.;  Feng,Tao;  Li,Lijuan;  Sun,Yanxia;  Huang,Jinling;  Deng,Tao;  Wang,Hengchang;  Sun,Hang
浏览  |  Adobe PDF(2158Kb)  |  收藏  |  浏览/下载：21/11  |  提交时间：2024/07/25
adaptation  alpine plants  evolutionary rates  genomic convergence  greenhouse morphology  high altitude  PHYLOGENETIC ANALYSIS  ARABIDOPSIS  EVOLUTION  PROTEIN  GENE  ALIGNMENT  PROGRAM  FAMILY  TOOL  BIOSYNTHESIS