Insights into the mechanisms involved in the fungal degradation of plastics

doi:10.1016/j.ecoenv.2023.115202

KIB OpenIR

	Insights into the mechanisms involved in the fungal degradation of plastics
	Okal,Eyalira Jacob; Heng,Gui; Magige,Ephie A.; Khan,Sehroon; Wu,Shixi; Ge,Zhiqiang; Zhang,Tianfu; Mortimer,Peter E.; Xu,Jianchu
	2023
发表期刊	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
ISSN	1090-2414
卷号	262 页码:115202
摘要	Fungi are considered among the most efficient microbial degraders of plastics, as they produce salient enzymes and can survive on recalcitrant compounds with limited nutrients. In recent years, studies have reported numerous species of fungi that can degrade different types of plastics, yet there remain many gaps in our un-derstanding of the processes involved in biodegradation. In addition, many unknowns need to be resolved regarding the fungal enzymes responsible for plastic fragmentation and the regulatory mechanisms which fungi use to hydrolyse, assimilate and mineralize synthetic plastics. This review aims to detail the main methods used in plastic hydrolysis by fungi, key enzymatic and molecular mechanisms, chemical agents that enhance the enzymatic breakdown of plastics, and viable industrial applications. Considering that polymers such as lignin, bioplastics, phenolics, and other petroleum-based compounds exhibit closely related characteristics in terms of hydrophobicity and structure, and are degraded by similar fungal enzymes as plastics, we have reasoned that genes that have been reported to regulate the biodegradation of these compounds or their homologs could equally be involved in the regulation of plastic degrading enzymes in fungi. Thus, this review highlights and provides insight into some of the most likely regulatory mechanisms by which fungi degrade plastics, target enzymes, genes, and transcription factors involved in the process, as well as key limitations to industrial upscaling of plastic biodegradation and biological approaches that can be employed to overcome these challenges.
关键词	Plastic biodegradation Pre-treatment Enzyme hydrolysis Prooxidants Molecular mechanisms SURFACE BINDING-PROTEIN WHITE-ROT FUNGI MICROBIAL-DEGRADATION MANGANESE PEROXIDASE LIGNIN PEROXIDASE GENE-EXPRESSION POLYETHYLENE TEREPHTHALATE TRANSCRIPTIONAL REGULATION BIOLOGICAL DEGRADATION ENZYMATIC DEGRADATION
DOI	10.1016/j.ecoenv.2023.115202
收录类别	SCI
WOS记录号	WOS:001030607500001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75468
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Okal,Eyalira Jacob,Heng,Gui,Magige,Ephie A.,et al. Insights into the mechanisms involved in the fungal degradation of plastics[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2023,262:115202.
APA	Okal,Eyalira Jacob.,Heng,Gui.,Magige,Ephie A..,Khan,Sehroon.,Wu,Shixi.,...&Xu,Jianchu.(2023).Insights into the mechanisms involved in the fungal degradation of plastics.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,262,115202.
MLA	Okal,Eyalira Jacob,et al."Insights into the mechanisms involved in the fungal degradation of plastics".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 262(2023):115202.

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