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Interactions between depolymerized fucosylated glycosaminoglycan and coagulation proteases or inhibitors 期刊论文
THROMBOSIS RESEARCH, 2016, 卷号: 146, 页码: 59-68
作者:  Xiao, Chuang;  Lian, Wu;  Zhou, Lutan;  Gao, Na;  Xua, Li;  Chen, Jun;  Wu, Mingyi;  Peng, Wenlie;  Zhao, Jinhua
浏览  |  Adobe PDF(5739Kb)  |  收藏  |  浏览/下载：368/95  |  提交时间：2017/01/05
Fucosylated Glycosaminoglycan  Coagulation Proteases  Biolayer Interferometry  Binding Kinetics  Structure-activity Relationship  
beta-Eliminative depolymerization of the fucosylated chondroitin sulfate and anticoagulant activities of resulting fragments 期刊论文
CARBOHYDRATE POLYMERS, 2015, 卷号: 127, 页码: 427-437
作者:  Gao, Na;  Lu, Feng;  Xiao, Chuang;  Yang, Lian;  Chen, Jun;  Zhou, Kai;  Wen, Dandan;  Li, Zi;  Wu, Mingyi;  Jiang, Jianmin;  Liu, Guangming;  Zhao, Jinhua;  Liu,GM (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,132 Lanhei Rd,Kunming 650201,Yunnan,Peoples R China.;  lgm13330555378@126.com;  zhao.jinhua@yahoo.com
浏览  |  Adobe PDF(2985Kb)  |  收藏  |  浏览/下载：619/151  |  提交时间：2015/07/20
Fucosylated Chondroitin Sulfate  Benzyl Esterification  Beta-elimination  Depolymerization  Anticoagulant  
Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 卷号: 112, 期号: 27, 页码: 8284-8289
作者:  Zhao, Longyan;  Wu, Mingyi;  Xiao, Chuang;  Yang, Lian;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Chen, Jun;  Chen, Jianchao;  Liu, Jikai;  Qin, Hongbo;  Zhao, Jinhua
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Anticoagulant  Inhibitors  Oligosaccharides  Carbohydrates  Drug Discovery  
Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 92, 页码: 257-269
作者:  Wu, Mingyi;  Wen, Dandan;  Gao, Na;  Xiao, Chuang;  Yang, Lian;  Xu, Li;  Lian, Wu;  Peng, Wenlie;  Jiang, Jianmin;  Zhao, Jinhua;  Jiang,JM (reprint author),Sun Yat Sen Univ,Sch Pharmaceut Sci,Guangzhou 510006,Guangdong,Peoples R China.;  lssjjm@mail.sysu.edu.cn;  zhao.jinhua@yahoo.com
浏览  |  Adobe PDF(1936Kb)  |  收藏  |  浏览/下载：345/110  |  提交时间：2015/06/29
Fucosylated Chondroitin Sulfate  Factor Xase Inhibitor  Anticoagulant  Antithrombotic  Structure-activity Relationship  
Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 4, 页码: 2063-2084
作者:  Wu, Mingyi;  Xu, Li;  Zhao, Longyan;  Xiao, Chuang;  Gao, Na;  Luo, Lan;  Yang, Lian;  Li, Zi;  Chen, Lingyun;  Zhao, Jinhua
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一种抑制内源性因子X酶活性的寡糖类化合物及其药物组合物 专利
专利类型: 发明, 专利号: CN201410549676.6, 申请日期: 2014-10-17, 公开日期: 2015-02-25
发明人:  赵金华;  何金星;  吴明一;  赵龙岩;  刘峙汶;  杨莲;  李姿;  高娜;  肖创;  徐丽;  陈钧;  周路坦.
Adobe PDF(3578Kb)  |  收藏  |  浏览/下载：348/15  |  提交时间：2015/06/29
东北岩高兰化学成分研究 期刊论文
中草药, 2014, 期号: 16, 页码: 2293-2298
作者:  张玉莲;  梅任强;  刘熙;  刘光明;  吴滨
浏览  |  Adobe PDF(772Kb)  |  收藏  |  浏览/下载：175/71  |  提交时间：2015/01/20
岩高兰科  东北岩高兰  三萜  二氢查耳酮  3β-羟基-21-烯-岩高兰三萜  肉桂醇  4′-羟基-α  槲皮素  Β-二氢查耳酮-2′-o-β-d-葡萄糖苷  金丝桃苷  
Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 卷号: 1830, 期号: 10, 页码: 4681-4691
作者:  Lian, Wu;  Wu, Mingyi;  Huang, Ning;  Gao, Na;  Xiao, Chuang;  Li, Zi;  Zhang, Zhigang;  Zheng, Yongtang;  Peng, Wenlie;  Zhao, Jinhua
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Glycosaminoglycan  Anti-human Immunodeficiency Virus Activity  Envelope Glycoprotein 120  Cluster Of Differentiation 4 Induced Epitope  Biolayer Interferometry  Structure-activity Relationship  
N-喹啉基取代的β-内酰胺类化合物及其药物组合物和合成方法与应用 专利
专利类型: 发明, 专利号: CN201310428596.0, 申请日期: 2013-09-18, 公开日期: 2014-01-22
发明人:  吴滨;  孙文武;  曹沛;  赵金华;  杨莲
Adobe PDF(1980Kb)  |  收藏  |  浏览/下载：235/9  |  提交时间：2016/12/19
Comparison of Physicochemical Characteristics and Anticoagulant Activities of Polysaccharides from Three Sea Cucumbers 期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 399-417
作者:  Luo, Lan;  Wu, Mingyi;  Xu, Li;  Lian, Wu;  Xiang, Jingying;  Lu, Feng;  Gao, Na;  Xiao, Chuang;  Wang, Shengmin;  Zhao, Jinhua
浏览  |  Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：610/95  |  提交时间：2013/07/24
Sea Cucumber  Polysaccharide  Fucosylated Chondroitin Sulfate  Sulfated Fucan  Glucan  Anticoagulant Activity