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基于酚酸类结构研究抗流感病毒、 新冠病毒前体药物 学位论文
: 中国科学院大学, 2022
作者:  侯博
Adobe PDF(7912Kb)  |  收藏  |  浏览/下载:54/0  |  提交时间:2024/05/14
乙酰化酚酸环, 流感病毒, 新冠病毒, 抑制剂  Acetylflicinic acid cycle, Flu virus, SARS-CoV-2, Inhibitors  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载:180/0  |  提交时间:2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
A new polysaccharide platform constructs self-adjuvant nanovaccines to enhance immune responses 期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2022, 卷号: 20, 期号: 1, 页码: 320
作者:  Chen, Sisi;  Yang, Liu;  Ou, Xia;  Li, Jin-Yu;  Zi, Cheng-Ting;  Wang, Hao;  Hu, Jiang-Miao;  Liu, Ye
浏览  |  Adobe PDF(7638Kb)  |  收藏  |  浏览/下载:61/15  |  提交时间:2024/04/30
Polysaccharide  Self-adjuvant  Nanovaccine  SARS-CoV-2  HIV  STRUCTURAL-CHARACTERIZATION  DENDRITIC CELLS  DRUG-DELIVERY  NANOPARTICLES  PARTICLES  CHITOSAN  GLYCOGEN  DESIGN  
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
作者:  Guo,Sheng;  Xie,Hang;  Lei,Yu;  Liu,Bin;  Zhang,Li;  Xu,Yechun;  Zuo,Zhili
浏览  |  Adobe PDF(3181Kb)  |  收藏  |  浏览/下载:148/39  |  提交时间:2022/04/02
SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation  
Which species does the virus like most: Binding modes study between SARS-CoV-2 S protein and ACE2 receptor 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2021, 卷号: 105, 页码: 107893
作者:  Guo,Sheng;  Yang,Jing;  Lei,Yu;  Liu,Bin;  Zhang,Wei;  Zhang,Li;  Zuo,Zhili
浏览  |  Adobe PDF(3681Kb)  |  收藏  |  浏览/下载:130/24  |  提交时间:2022/04/02
SARS-CoV-2  COVID-19  Homology modeling  Molecular dynamics simulation  Binding free energy  CORONAVIRUS SPIKE PROTEIN  ACTIVATION  GROMACS  ENTRY