中文版 | English

在结果中检索

KIB OpenIR

浏览/检索结果: 共9条，第1-9条 帮助

已选(0)清除 条数/页：   排序方式：
Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and P53 期刊论文
出版物, 3111, 期号: 0, 页码: 1-37
作者:  Baihe Chen;  Di Lu;  Yujuan Fu;  Jingwen Zhang;  Xiaobo Huang;  Shiping Cao;  Dingli Xu;  Jianping Bin;  Masafumi Kitakaze;  Qiaobing Huang;  Yulin Liao
Adobe PDF(1769Kb)  |  收藏  |  浏览/下载：357/1  |  提交时间：2017/07/24
Cardiac Rupture  Olmesartan  P53  Gdf-15  Aldosterone  Myocardial Infarction  
新型天然铁死亡诱导剂的筛选及作用机制研究 学位论文
: 中国科学院大学, 2022
作者:  赵越勤
Adobe PDF(5494Kb)  |  收藏  |  浏览/下载：56/0  |  提交时间：2024/05/14
肿瘤，天然产物，铁死亡，溶酶体，p53  Cancer, Nature products, Ferroptosis, Lysosome, p53  
Unusual prenylated phenols with antioxidant activities from Ganoderma cochlear 期刊论文
FOOD CHEMISTRY, 2014, 卷号: 55, 期号: 47, 页码: 6490-6494
作者:  Peng,XingRong;  Liu,JieQing;  Wang,CuiFang;  Han,ZhongHui;  Shu,Yi;  Li,XuYang;  Zhou,Lin;  Qiu,MingHua;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  mhchiu@mail.kib.ac.cn
浏览  |  Adobe PDF(802Kb)  |  收藏  |  浏览/下载：369/98  |  提交时间：2015/01/20
Negative Regulator  Xenopus Embryos  C-cbl  Pathway  Protein  P53  Kinase  Degradation  Disease  Mechanisms  
Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 3, 页码: 841-852
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Li, Jingxia;  Deng, Xu;  Zhao, Qin-shi;  Huang, Chuanshu
浏览  |  Adobe PDF(3282Kb)  |  收藏  |  浏览/下载：392/75  |  提交时间：2014/05/16
Cheliensisin a  Apoptosis  Colon Cancer  P53  Chemotherapeutic Agent  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
浏览  |  Adobe PDF(6299Kb)  |  收藏  |  浏览/下载：338/52  |  提交时间：2015/05/14
One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
浏览  |  Adobe PDF(2066Kb)  |  收藏  |  浏览/下载：345/69  |  提交时间：2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53  
Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 卷号: 164, 期号: 2B, 页码: 731-742
作者:  Wang, Ning;  Pan, Weidong;  Zhu, Meifen;  Zhang, Maosheng;  Hao, Xiaojian;  Liang, Guangyi;  Feng, Yibin
浏览  |  Adobe PDF(1960Kb)  |  收藏  |  浏览/下载：431/108  |  提交时间：2012/07/25
Fangchinoline  Autophagy  P53  Sestrin2  Hepatocellular Carcinoma  Ampk  
Grifolin, a potent antitumour natural product upregulates death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells 期刊论文
EUROPEAN JOURNAL OF CANCER, 2011, 卷号: 47, 期号: 2, 页码: 316-325
作者:  Luo, Xiang-jian;  Li, Li-li;  Deng, Qi-pan;  Yu, Xin-fang;  Yang, Li-fang;  Luo, Fei-jun;  Xiao, Lan-bo;  Chen, Xiao-yan;  Ye, Mao;  Liu, Ji-kai;  Cao, Ya
Adobe PDF(1466Kb)  |  收藏  |  浏览/下载：600/171  |  提交时间：2012/04/10
Grifolin  Mushroom  Dapk1  P53  Apoptosis  
Cycloartane Triterpenoids from Cimicifuga yunnanensis induce Apoptosis of Breast Cancer Cells (MCF7) via p53-dependent Mitochondrial Signaling Pathway 期刊论文
PHYTOTHERAPY RESEARCH, 2011, 卷号: 25, 期号: 1, 页码: 17-24
作者:  Fang, Zhong-Ze;  Nian, Yin;  Li, Wei;  Wu, Jing-Jing;  Ge, Guang-Bo;  Dong, Pei-Pei;  Zhang, Yan-Yan;  Qiu, Ming-Hua;  Liu, Lei;  Yang, Ling
Adobe PDF(982Kb)  |  收藏  |  浏览/下载：391/130  |  提交时间：2012/04/10
Cycloartane Triterpenoids  Mcf7  P53  Apoptosis  Mitochondrial Membrane Potential  Caspase-7