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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
作者:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载：386/1  |  提交时间：2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：73/11  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
作者:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
浏览  |  Adobe PDF(6313Kb)  |  收藏  |  浏览/下载：232/49  |  提交时间：2022/04/02
Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS  
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity 期刊论文
BMC Cancer, 2019, 卷号: 19, 期号: 1
作者:  Wang,Ning;  Fan,Yanhua;  Yuan,Chun-Mao;  Song,Jialei;  Yao,Yao;  Liu,Wuling;  Gajendran,Babu;  Zacksenhaus,Eldad;  Li,Yanmei;  Liu,Jielin;  Hao,Xiao Jiang;  Ben-David,Yaacov
收藏  |  浏览/下载：186/0  |  提交时间：2019/08/13
Cancer  Leukemia  Chinese medicinal plant  Melia azedarach  Drug screen  ERK1/2 agonists  Differentiation  Apoptosis  
尖刀唇石斛化学成分及降脂活性天然产物研究 学位论文
硕士: 云南大学, 2019
作者:  颜莎
Adobe PDF(3354Kb)  |  收藏  |  浏览/下载：248/1  |  提交时间：2022/08/29
尖刀唇石斛  酚性化合物  降脂  减肥  ERK1/2 蛋白  
microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 10, 页码: 16633-16641
作者:  Wei, Ran;  Yang, Qin;  Han, Bing;  Li, Yan;  Yao, Kun;  Yang, Xiuyu;  Chen, Zexi;  Yang, Shanshan;  Zhou, Jiaqi;  Li, Meizhang;  Yu, Haijing;  Yu, Min;  Cui, Qinghua
浏览  |  Adobe PDF(12068Kb)  |  收藏  |  浏览/下载：470/43  |  提交时间：2017/04/19
Microrna-375  Colorectal Cancer  Jak2/stat3 Pathway  Map3k8/erk Pathway  Atg7  
Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 40, 页码: 42704-42716
作者:  Luo, Xiangjian;  Yang, Lifang;  Xiao, Lanbo;  Xia, Xiaofeng;  Dong, Xin;  Zhong, Juanfang;  Liu, Ying;  Li, Namei;  Chen, Ling;  Li, Hongde;  Li, Wei;  Liu, Wenbin;  Yu, Xinfang;  Chen, Hanyong;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Bode, Ann;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
浏览  |  Adobe PDF(5262Kb)  |  收藏  |  浏览/下载：264/45  |  提交时间：2016/06/27
Grifolin  Erk1/2  Dnmt1  Metastasis  
Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 卷号: 164, 期号: 7, 页码: 1883-1898
作者:  Yue, Grace G. L.;  Fan, Jun-Ting;  Lee, Julia K. M.;  Zeng, Guang-Zhi;  Ho, Tina W. F.;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Tan, Ning-Hua;  Lau, Clara B. S.
浏览  |  Adobe PDF(2713Kb)  |  收藏  |  浏览/下载：452/90  |  提交时间：2012/07/25
Cyclopeptide  Ra-v  Angiogenesis  Erk1  2  Rubia Yunnanensis  Huvec  Hmec-1  Endothelial Cells  
DAPK1 mediates the G1 phase arrest in human nasopharyngeal carcinoma cells induced by grifolin, a potential antitumor natural product 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 卷号: 670, 期号: 2-3, 页码: 427-434
作者:  Luo, Xiang-jian;  Li, Wei;  Yang, Li-fang;  Yu, Xin-fang;  Xiao, Lan-bo;  Tang, Min;  Dong, Xin;  Deng, Qi-pan;  Bode, Ann M.;  Liu, Ji-kai;  Cao, Ya
Adobe PDF(1137Kb)  |  收藏  |  浏览/下载：539/162  |  提交时间：2012/04/10
Grifolin  Dapk1  Cell Cycle  P21  Erk1/2  Npc  Mushroom  
Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, induces cell-cycle arrest in G1 phase via the ERK1/2 pathway 期刊论文
CANCER LETTERS, 2007, 卷号: 258, 期号: 2, 页码: 199-207
作者:  Ye, Mao;  Luo, Xiangjian;  Li, Lili;  Shi, Ying;  Tan, Ming;  Weng, Xinxian;  Li, Wei;  Liu, Jikai;  Cao, Ya
Adobe PDF(570Kb)  |  收藏  |  浏览/下载：388/123  |  提交时间：2011/12/19
Grifolin  Cell Cycle  Erk1/2  Erk5