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Redox Dual-Responsive and O-2-Evolving Theranostic Nanosystem for Highly Selective Chemotherapy against Hypoxic Tumors 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 90-103
作者:  Chen, Huachao;  Li, Fei;  Yao, Yongrong;  Wang, Zhe;  Zhang, Zhihao;  Tan, Ninghua
浏览  |  Adobe PDF(3409Kb)  |  收藏  |  浏览/下载:379/87  |  提交时间:2019/07/29
cancer  theranostic system  hypoxic tumor  ROS/GSH dual-activatable  cyclopeptide RA-V  fluorescence imaging  
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
作者:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
浏览  |  Adobe PDF(4110Kb)  |  收藏  |  浏览/下载:319/101  |  提交时间:2018/05/08
Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-kappa B signaling pathways 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2015, 卷号: 1853, 期号: 8, 页码: 1827-1840
作者:  Leung, Hoi-Wing;  Wang, Zhe;  Yue, Grace Gar-Lee;  Zhao, Si-Meng;  Lee, Julia Kin-Ming;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Lau, Clara Bik-San;  Tan, Ning-Hua;  Lau,CBS (reprint author),Chinese Univ Hong Kong,Inst Chinese Med,Shatin,Hong Kong,Peoples R China.;  claralau@cuhk.edu.hk;  nhtan@mail.kib.ac.cn
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Cyclopeptide  Cell Adhesion  Cell Invasion  Metastasis  Breast Cancer  
Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 卷号: 267, 期号: 1, 页码: 95-103
作者:  Fang, Xian-Ying;  Chen, Wei;  Fan, Jun-Ting;  Song, Ran;  Wang, Lu;  Gu, Yan-Hong;  Zeng, Guang-Zhi;  Shen, Yan;  Wu, Xue-Feng;  Tan, Ning-Hua;  Xu, Qiang;  Sun, Yang
浏览  |  Adobe PDF(1855Kb)  |  收藏  |  浏览/下载:895/171  |  提交时间:2013/03/18
Ra-v  Cyclopeptide  Mitochondrial Apoptosis Pathway  Pi3k/akt  Breast Cancer  
Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2012, 卷号: 30, 期号: 6, 页码: 1213-1225
作者:  Zhao Simeng;  Kuang Bin;  Peng Wenwen;  He Wenjun;  Xu Huimin;  Ji Changjiu;  Han Jing;  Zheng Yuqing;  Song Weiwu;  Tan Ninghu
浏览  |  Adobe PDF(522Kb)  |  收藏  |  浏览/下载:515/110  |  提交时间:2014/04/02
Cyclopeptide  Traditional Chinese Medicine  Chemical Constituent  
An in vitro system to study cyclopeptide heterophyllin B biosynthesis in the medicinal plant Pseudostellaria heterophylla 期刊论文
PLANT CELL TISSUE AND ORGAN CULTURE, 2012, 卷号: 108, 期号: 1, 页码: 137-145
作者:  Xu, Wenyan;  Zhu, Hongtao;  Tan, Ninghua;  Tang, Jun;  Zhang, Yingjun;  Cerny, Ron L.;  Du, Liangcheng
Adobe PDF(491Kb)  |  收藏  |  浏览/下载:467/169  |  提交时间:2012/06/07
Heterophyllin b  Plant Cyclopeptide  Biosynthesis  Pseudostellaria Heterophylla  Traditional Chinese Medicine  
Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 卷号: 164, 期号: 7, 页码: 1883-1898
作者:  Yue, Grace G. L.;  Fan, Jun-Ting;  Lee, Julia K. M.;  Zeng, Guang-Zhi;  Ho, Tina W. F.;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Tan, Ning-Hua;  Lau, Clara B. S.
浏览  |  Adobe PDF(2713Kb)  |  收藏  |  浏览/下载:584/126  |  提交时间:2012/07/25
Cyclopeptide  Ra-v  Angiogenesis  Erk1  2  Rubia Yunnanensis  Huvec  Hmec-1  Endothelial Cells  
Two new minor cyclopeptides from Sagina japonica (Caryophyllaceae) 期刊论文
FITOTERAPIA, 2009, 卷号: 80, 期号: 3, 页码: 192-195
作者:  Jia, Ai-qun;  Tan, Ning-hua;  Zhou, Jun
Adobe PDF(259Kb)  |  收藏  |  浏览/下载:454/136  |  提交时间:2012/03/21
Cyclopeptide  Agina Japonica  Sajaponicin a  Sajaponicin b  Structure  
Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri 期刊论文
HELVETICA CHIMICA ACTA, 2009, 卷号: 92, 期号: 6, 页码: 1118-1125
作者:  Yuan, Lin;  Zhao, Pei-Ji;  Ma, Juan;  Lu, Chun-Hua;  Shen, Yue-Mao
Adobe PDF(229Kb)  |  收藏  |  浏览/下载:427/169  |  提交时间:2012/03/21
Cyclopeptide  Agina Japonica  Sajaponicin a  Sajaponicin b  Structure  
New cyclopeptides in Arenaria oreophila (Caryophyllaceae) 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2007, 卷号: 9, 期号: 6, 页码: 569-574
作者:  Jia, Ai-Qun;  Tan, Ning-Hua;  Zhou, Jun
Adobe PDF(126Kb)  |  收藏  |  浏览/下载:373/114  |  提交时间:2011/11/24
Arenaria Oreophila  Caryophyllaceae  Cyclopeptide  Arenariphilin g  Arenariphilin h