Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri
Yuan, Lin1,2; Zhao, Pei-Ji1; Ma, Juan1; Lu, Chun-Hua1; Shen, Yue-Mao1
2009
发表期刊HELVETICA CHIMICA ACTA
ISSN0018-019X
卷号92期号:6页码:1118-1125
摘要Five new diterpenoids, named botryosphaerins A-E (1-5, resp.), including one labdane and four tetranorlabdane diterpenes, were isolated from the solid culture of the endophytic fungal strain Botryosphaeria sp. MHF of Maytenus hookeri, together with seven known diterpenoids, namely 13,14,15,16-tetranorlabd-7-ene-19,6 beta: 12,17-diolide (6), acrostalidic acid (7), acrostalic acid (8), agathic acid (9). isocupressic acid (10), LL-Z1271 beta (11), and CJ-14445 (12). The structures of all compounds were established on the basis of comprehensive spectroscopic studies. The relative configurations of 1 and 2 were determined by single-crystal X-ray diffraction analyses. All compounds except 4 were evaluated for their inhibitory activities against several pathogenic bacterial and fungal strains. However, only compound 12 showed significant inhibitions against Candida albicans, Saccharomyces cerevisiae, and Penicillium avellaneum UC-4376 with nystatin as a positive control.
关键词Cyclopeptide Agina Japonica Sajaponicin a Sajaponicin b Structure
学科领域Chemistry, Multidisciplinary
收录类别SCI ; IC
语种英语
WOS记录号WOS:000267738800011
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4852
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Kunming Univ, Sch Chem, Kunming 650031, Peoples R China
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Yuan, Lin,Zhao, Pei-Ji,Ma, Juan,et al. Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri[J]. HELVETICA CHIMICA ACTA,2009,92(6):1118-1125.
APA Yuan, Lin,Zhao, Pei-Ji,Ma, Juan,Lu, Chun-Hua,&Shen, Yue-Mao.(2009).Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri.HELVETICA CHIMICA ACTA,92(6),1118-1125.
MLA Yuan, Lin,et al."Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri".HELVETICA CHIMICA ACTA 92.6(2009):1118-1125.
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