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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Sesquiterpenoids from Alpinia oxyphylla with GLP-1 Stimulative Effects through Ca2+/CaMKII and PKA Pathways and Multiple-Enzyme Inhibition
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 43, 页码: 16148-16159
作者:
Cui,Can
;
Wu,Sheng-Li
;
Chen,Ji-Jun
;
Gongpan,Pianchou
;
Guan,Min
;
Geng,Chang-An
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Adobe PDF(2550Kb)
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浏览/下载:5/3
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提交时间:2024/07/10
Alpinia oxyphylla
sesquiterpenoids
GLP-1 stimulation
Ca2+/CaMKII and PKA pathways
alpha-glucosidase and PTP1B inhibitory activity
The Extracts of Dendrobium Alleviate Dry Eye Disease in Rat Model by Regulating Aquaporin Expression and MAPKs/NF-kappa B Signalling
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 19, 页码: 11195
作者:
Ling, Jiawei
;
Chan, Chung-Lap
;
Ho, Chi-Yan
;
Gao, Xun
;
Tsang, Sin-Man
;
Leung, Ping-Chung
;
Hu, Jiang-Miao
;
Wong, Chun-Kwok
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Adobe PDF(3779Kb)
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浏览/下载:31/6
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提交时间:2024/04/30
dry eye disease
Dendrobium
aquaporin
scopolamine
human cornea keratocytes
TNF-ALPHA
ACTIVATION
CLASSIFICATION
INFLAMMATION
DEFINITION
IL-1-BETA
APOPTOSIS
PATHWAYS
STRESS
MMP-9
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance
期刊论文
JOURNAL OF ENDOCRINOLOGY, 2022, 卷号: 254, 期号: 3, 页码: 151-165
作者:
Qin, Wanying
;
Zhang, Ting
;
Ge, Mingxia
;
Zhou, Huimin
;
Xu, Yuhui
;
Mu, Rongfang
;
Huang, Chaoguang
;
Liu, Daowei
;
Huang, Bangrui
;
Wang, Qian
;
Kong, Qinghua
;
Kong, Qingpeng
;
Li, Fei
;
Xiong, Wenyong
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Adobe PDF(9525Kb)
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浏览/下载:36/10
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提交时间:2024/04/30
RACK1
bile acid
glucose metabolism
insulin sensitivity
ENDOPLASMIC-RETICULUM STRESS
C-KINASE 1
HEPATOCELLULAR-CARCINOMA
STEROL 12-ALPHA-HYDROXYLASE
DOWN-REGULATION
ER STRESS
KAPPA-B
RECEPTOR
ACTIVATION
GROWTH
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:
Yang, Xiao-Tong
;
Li, Tian-Ze
;
Geng, Chang-An
;
Liu, Pei
;
Chen, Ji-Jun
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Adobe PDF(1348Kb)
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浏览/下载:41/9
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提交时间:2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol
alpha-glucosidase inhibitors
PTP1B inhibitors
Enzyme kinetics
TYROSINE-PHOSPHATASE 1B
DIABETES-MELLITUS
EPIDEMIOLOGY
New insights into the taxonomy of the genus Cantharellus in China: epityfication of C. yunnanensis WF Chiu and the first record of C. cibarius Fr.
期刊论文
CRYPTOGAMIE MYCOLOGIE, 2021, 卷号: 42, 期号: 3, 页码: 25-37
作者:
Shao,Shi-Cheng
;
Liu,Pei-Gui
;
Wei,Tie-Zheng
;
Herrera,Mariana
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浏览/下载:78/0
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提交时间:2022/04/02
Hydnaceae
Cantharellus cibarius complex
epitypification
taxonomic revision
tef-1 alpha
Methanolic extract of Cariniana rubra Gardner ex Miers stem bark negatively regulate the leukocyte migration and TNF-alpha and up-regulate the annexin-A1 expression
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113778
作者:
Paulino Brandao Silva,Donata Norman
;
Adriana,Flach
;
de Oliveira Martins,Domingos Tabajara
;
Borges,Quessi Irias
;
Nunes Lindote,Marcus Vitor
;
Ramalho Zoratti,Marco Tulio
;
de Oliveira,Ruberlei Godinho
;
Vieira Torquato,Heron Fernandes
;
Gazoni,Vanessa Fatima
;
Alves da Costa,Luiz Antonio Mendonca
;
Alexandre de Souza,Edineide Cristina
;
Araujo da Silva,Felipe Moura
;
Arunachalam,Karuppusamy
;
Damazo,Amilcar Sabino
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浏览/下载:51/0
  |  
提交时间:2022/04/02
Cariniana rubra, anti-inflammatory
Air pouch
TNF-alpha
Annexin A1
Gallic acid
Terpenes
Mice
GENE-EXPRESSION
INFLAMMATION
Bitter Melon and Diabetes Mellitus
期刊论文
FOOD REVIEWS INTERNATIONAL, 2021
作者:
Gao,Ya
;
Li,Xian
;
Huang,Yanjie
;
Chen,Jianchao
;
Qiu,Minghua
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浏览/下载:76/0
  |  
提交时间:2022/04/02
Bitter melon
diabetes mellitus
crude extracts
phyto-metabolites
hypoglycemic mechanism
MOMORDICA-CHARANTIA L.
11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1
ALPHA-GLUCOSIDASE INHIBITION
INSULIN-RESISTANCE
ANTIDIABETIC ACTIVITIES
GUT MICROBIOTA
STRUCTURAL-CHARACTERIZATION
PHENOLIC-COMPOUNDS
OXIDATIVE STRESS
PROTEIN-KINASE
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Li,Tian-Ze
;
Hu,Jing
;
Huang,Xiao-Yan
;
Zhang,Xue-Mei
;
Guo,Yuan-Qiang
;
Geng,Chang-An
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Adobe PDF(2762Kb)
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浏览/下载:147/62
  |  
提交时间:2022/04/02
Alpinia katsumadai
Katsumadainols B-1-B-15
Natural products
Structure elucidation
Biological activity
TYROSINE-PHOSPHATASE 1B
GLYCOGEN-PHOSPHORYLASE
ALPHA-GLUCOSIDASE
ABSOLUTE-CONFIGURATION
STRUCTURE ELUCIDATION
DUAL INHIBITION
SEEDS
CONSTITUENT
DERIVATIVES
CHALCONE
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors
期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Huang,Xiao-Yan
;
Hu,Jing
;
Zhang,Xu-Ke
;
Guo,Yuan-Qiang
;
Zhang,Xue-Mei
;
Geng,Chang-An
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Adobe PDF(5184Kb)
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  |  
浏览/下载:100/28
  |  
提交时间:2022/04/02
Amomum tsao-ko
Amomutsaokins A-H
Flavanol-menthane conjugates
PTP1B selective inhibitors
alpha-Glucosidase inhibitors
ANTIOXIDANT ACTIVITY
ESSENTIAL OIL
CONSTITUENTS
TANNINS
CREVOST
ACID
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Li,Tian-Ze
;
Hu,Jing
;
Zhang,Xue-Mei
;
Geng,Chang-An
浏览
  |  
Adobe PDF(2223Kb)
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收藏
  |  
浏览/下载:134/56
  |  
提交时间:2022/04/02
Alpinia katsumadai
Katsumadainols A(1)-A(16)
PTP1B/TCPTP selective inhibitors
alpha-glucosidase inhibitors
Antidiabetic effects
THEORETICAL CALCULATION
ABSOLUTE-CONFIGURATION
SEEDS
BLEPHAROCALYXINS
ADDUCT
MOIETY