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Sesquiterpenoids from Alpinia oxyphylla with GLP-1 Stimulative Effects through Ca2+/CaMKII and PKA Pathways and Multiple-Enzyme Inhibition 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 43, 页码: 16148-16159
作者:  Cui,Can;  Wu,Sheng-Li;  Chen,Ji-Jun;  Gongpan,Pianchou;  Guan,Min;  Geng,Chang-An
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Alpinia oxyphylla  sesquiterpenoids  GLP-1 stimulation  Ca2+/CaMKII and PKA pathways  alpha-glucosidase and PTP1B inhibitory activity  
The Extracts of Dendrobium Alleviate Dry Eye Disease in Rat Model by Regulating Aquaporin Expression and MAPKs/NF-kappa B Signalling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 19, 页码: 11195
作者:  Ling, Jiawei;  Chan, Chung-Lap;  Ho, Chi-Yan;  Gao, Xun;  Tsang, Sin-Man;  Leung, Ping-Chung;  Hu, Jiang-Miao;  Wong, Chun-Kwok
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dry eye disease  Dendrobium  aquaporin  scopolamine  human cornea keratocytes  TNF-ALPHA  ACTIVATION  CLASSIFICATION  INFLAMMATION  DEFINITION  IL-1-BETA  APOPTOSIS  PATHWAYS  STRESS  MMP-9  
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance 期刊论文
JOURNAL OF ENDOCRINOLOGY, 2022, 卷号: 254, 期号: 3, 页码: 151-165
作者:  Qin, Wanying;  Zhang, Ting;  Ge, Mingxia;  Zhou, Huimin;  Xu, Yuhui;  Mu, Rongfang;  Huang, Chaoguang;  Liu, Daowei;  Huang, Bangrui;  Wang, Qian;  Kong, Qinghua;  Kong, Qingpeng;  Li, Fei;  Xiong, Wenyong
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RACK1  bile acid  glucose metabolism  insulin sensitivity  ENDOPLASMIC-RETICULUM STRESS  C-KINASE 1  HEPATOCELLULAR-CARCINOMA  STEROL 12-ALPHA-HYDROXYLASE  DOWN-REGULATION  ER STRESS  KAPPA-B  RECEPTOR  ACTIVATION  GROWTH  
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
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(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
New insights into the taxonomy of the genus Cantharellus in China: epityfication of C. yunnanensis WF Chiu and the first record of C. cibarius Fr. 期刊论文
CRYPTOGAMIE MYCOLOGIE, 2021, 卷号: 42, 期号: 3, 页码: 25-37
作者:  Shao,Shi-Cheng;  Liu,Pei-Gui;  Wei,Tie-Zheng;  Herrera,Mariana
收藏  |  浏览/下载:108/0  |  提交时间:2022/04/02
Hydnaceae  Cantharellus cibarius complex  epitypification  taxonomic revision  tef-1 alpha  
Methanolic extract of Cariniana rubra Gardner ex Miers stem bark negatively regulate the leukocyte migration and TNF-alpha and up-regulate the annexin-A1 expression 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113778
作者:  Paulino Brandao Silva,Donata Norman;  Adriana,Flach;  de Oliveira Martins,Domingos Tabajara;  Borges,Quessi Irias;  Nunes Lindote,Marcus Vitor;  Ramalho Zoratti,Marco Tulio;  de Oliveira,Ruberlei Godinho;  Vieira Torquato,Heron Fernandes;  Gazoni,Vanessa Fatima;  Alves da Costa,Luiz Antonio Mendonca;  Alexandre de Souza,Edineide Cristina;  Araujo da Silva,Felipe Moura;  Arunachalam,Karuppusamy;  Damazo,Amilcar Sabino
收藏  |  浏览/下载:83/0  |  提交时间:2022/04/02
Cariniana rubra, anti-inflammatory  Air pouch  TNF-alpha  Annexin A1  Gallic acid  Terpenes  Mice  GENE-EXPRESSION  INFLAMMATION  
Bitter Melon and Diabetes Mellitus 期刊论文
FOOD REVIEWS INTERNATIONAL, 2021
作者:  Gao,Ya;  Li,Xian;  Huang,Yanjie;  Chen,Jianchao;  Qiu,Minghua
收藏  |  浏览/下载:104/0  |  提交时间:2022/04/02
Bitter melon  diabetes mellitus  crude extracts  phyto-metabolites  hypoglycemic mechanism  MOMORDICA-CHARANTIA L.  11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1  ALPHA-GLUCOSIDASE INHIBITION  INSULIN-RESISTANCE  ANTIDIABETIC ACTIVITIES  GUT MICROBIOTA  STRUCTURAL-CHARACTERIZATION  PHENOLIC-COMPOUNDS  OXIDATIVE STRESS  PROTEIN-KINASE  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
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Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
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Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
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Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY