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Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 2, 页码: 2681-2693
作者:  Cheng, Xin;  Liu, Yong-Qiang;  Wang, Gui-Zhen;  Yang, Li-Na;  Lu, Yong-Zhi;  Li, Xin-Chun;  Zhou, Bo;  Qu, Li-Wei;  Wang, Xiao-Lu;  Cheng, Yong-Xian;  Liu, Jinsong;  Tao, Sheng-Ce;  Zhou, Guang-Biao
浏览  |  Adobe PDF(7649Kb)  |  收藏  |  浏览/下载:227/27  |  提交时间:2017/04/18
Proteome Microarray  6-o-angeloylplenolin  Stat3 Inhibitor  Skp2  Lung Cancer  
Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 33, 页码: 34953-34967
作者:  Liu,Yong-Qiang;  Wang,Xiao-Lu;  Cheng,Xin;  Lu,Yong-Zhi;  Wang,Gui-Zhen;  Li,Xin-Chun;  Zhang,Jian;  Wen,Zhe-Sheng;  Huang,Zhi-Liang;  Gao,Qin-Lei;  Yang,Li-Na;  Cheng,Yong-Xian;  Tao,Sheng-Ce;  Liu,Jinsong;  Zhou,Guang-Biao
浏览  |  Adobe PDF(2162Kb)  |  收藏  |  浏览/下载:347/72  |  提交时间:2016/01/19
Skp1  Lung Cancer  Structure-based High-throughput Virtual Screening  Inhibitors  6-o-angeloylplenolin  
Ethoxysanguinarine Induces Inhibitory Effects and Downregulates CIP2A in Lung Cancer Cells 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 2, 页码: 113-118
作者:  Liu, Zi;  Ma, Liang;  Wen, Zhe-Sheng;  Cheng, Yong-Xian;  Zhou, Guang-Biao
浏览  |  Adobe PDF(415Kb)  |  收藏  |  浏览/下载:459/83  |  提交时间:2014/04/09
Ethoxysanguinarine  Cip2a  Lung Cancer  Cell Proliferation  Apoptosis  
Small compound bigelovin exerts inhibitory effects and triggers proteolysis of E2F1 in multiple myeloma cells 期刊论文
CANCER SCIENCE, 2013, 卷号: 104, 期号: 12, 页码: 1697-1704
作者:  Liu, Jing-Lei;  Zeng, Guang-Zhi;  Liu, Xiao-Li;  Liu, Yong-Qiang;  Hu, Zhong-Guo;  Liu, Ying;  Tan, Ning-Hua;  Zhou, Guang-Biao
浏览  |  Adobe PDF(1224Kb)  |  收藏  |  浏览/下载:290/69  |  提交时间:2015/05/13
一种STAT3抑制剂及其在制药业中的应用 专利
专利类型: 发明, 专利号: CN201310181337.2, 申请日期: 2013-05-16, 公开日期: 2014-11-26
发明人:  周光飚;  程永现;  刘永强
Adobe PDF(1866Kb)  |  收藏  |  浏览/下载:118/6  |  提交时间:2016/12/19
Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 7, 页码: e21930
作者:  Liu, Ying;  Chen, Xiao-Qin;  Liang, Heng-Xing;  Zhang, Feng-Xiang;  Zhang, Bo;  Jin, Jie;  Chen, Yong-Long;  Cheng, Yong-Xian;  Zhou, Guang-Biao
Adobe PDF(877Kb)  |  收藏  |  浏览/下载:554/131  |  提交时间:2012/03/16
Nf-kappa-b  Cell-cycle Control  Overcomes Drug-resistance  Centipeda-minima  Antitumor-activity  Kinase-activity  Human Cancer  In-vitro  Activation  Expression  
Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 5, 页码: e20159
作者:  Ma, Liang;  Wen, Zhe-Sheng;  Liu, Zi;  Hu, Zheng;  Ma, Jun;  Chen, Xiao-Qin;  Liu, Yong-Qiang;  Pu, Jian-Xin;  Xiao, Wei-Lie;  Sun, Han-Dong;  Zhou, Guang-Biao
Adobe PDF(634Kb)  |  收藏  |  浏览/下载:393/127  |  提交时间:2012/03/16
Gastric-cancer  Breast-cancer  Phospho-akt  Smoking  Cells  Carcinoma  Survival  Leukemia  China  
血根碱类化合物在制备防治癌症的药物中的用途和药物组合物 专利
专利类型: 发明, 专利号: CN201110112769.9, 申请日期: 2011-05-03, 公开日期: 2012-11-07
发明人:  周光飚;  程永现;  马亮;  吕青;  刘姿
Adobe PDF(739Kb)  |  收藏  |  浏览/下载:127/8  |  提交时间:2016/12/19
Apoptosis Inducement of Bigelovin from Inula helianthus-aquatica on Human Leukemia U937 Cells 期刊论文
PHYTOTHERAPY RESEARCH, 2009, 卷号: 23, 期号: 6, 页码: 885-891
作者:  Zeng, Guang-Zhi;  Tan, Ning-Hua;  Ji, Chang-Jiu;  Fan, Jun-Ting;  Huang, Huo-Qiang;  Han, Hong-Jin;  Zhou, Guang-Biao
Adobe PDF(300Kb)  |  收藏  |  浏览/下载:417/140  |  提交时间:2012/03/21
Bigelovin  Inula Helianthus-aquatica  Cancer Cells  Apoptosis  U937  
Two new terpene glucosides and antitumor agents from Centipeda minima 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2009, 卷号: 11, 期号: 8, 页码: 732-736
作者:  Ding, Lin-Fen;  Liu, Ying;  Liang, Heng-Xing;  Liu, Da-Peng;  Zhou, Guang-Biao;  Cheng, Yong-Xian
Adobe PDF(110Kb)  |  收藏  |  浏览/下载:216/85  |  提交时间:2012/03/21
Centipeda Minima  Compositae  Terpene Glucosides  Cytotoxicity