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Bioactive triterpenoids from the traditional Chinese medicine Swertia mileensis 期刊论文
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 55, 页码: 1-5
作者:  Yuan,Xin;  Yan,Qin;  Hu,Hong;  He,Xiao-Ping;  Wang,Li-Xia;  Liu,Yan-Chun;  Liu,Yan;  Guo,Kai;  Li,Sheng-Hong
浏览  |  Adobe PDF(592Kb)  |  收藏  |  浏览/下载：53/14  |  提交时间：2024/07/22
Swertia mileensis  Gentianaceae  Triterpenoids  Anti-inflammatory activity  Cytotoxicity  
Characterization of two chimeric sesterterpene synthases from a fungal symbiont isolated from a sesterterpenoid-producing Lamiaceae plant Leucosceptrum canum 期刊论文
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 1, 页码: 107469
作者:  Li,Desen;  Yang,Minjie;  Mu,Rongfang;  Luo,Shihong;  Chen,Yuegui;  Li,Wenyuan;  Wang,An;  Guo,Kai;  Liu,Yan;  Li,Shenghong
浏览  |  Adobe PDF(1293Kb)  |  收藏  |  浏览/下载：63/15  |  提交时间：2024/07/22
Sesterterpenoids  Chimeric sesterterpene synthases  Plant symbiotic fungi  Alternaria alternata  Leucosceptrum canum  Anti-adipogenic activity  GLANDULAR TRICHOMES  ALTERNARIA-ALTERNATA  HARBOR  
Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 210, 页码: 113642
作者:  Liu,Jie;  Yan,Qin;  Wang,Li-Xia;  He,Xiao-Ping;  Hu,Hong;  Liu,Yan-Chun;  Li,Dan;  Liu,Yan;  Guo,Kai;  Li,Sheng-Hong
浏览  |  Adobe PDF(643Kb)  |  收藏  |  浏览/下载：64/9  |  提交时间：2024/07/22
Swertia pseudochinensis Hara  Gentianaceae  Secoiridoids  Anti-inflammatory activity  NATURALLY-OCCURRING IRIDOIDS  CHEMICAL-CONSTITUENTS  PART  BIOTRANSFORMATION  GENTIOPICROSIDE  BIOSYNTHESIS  GLUCOSIDES  
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载：110/18  |  提交时间：2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Melanin precursors mediated adaption to temperature changes in fungus and animal via inhibition of lipid-mediated ferroptosis 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2023
作者:  Yang,Xiaoyu;  Chen,Yonghong;  Zhang,Longlong;  He,Jiangbo;  Wu,Qunfu;  Li,Shuhong;  Wang,Donglou;  Gou,Jianghui;  Wu,Zhuang;  Zhang,Keqin;  Li,Shenghong;  Niu,Xuemei
浏览  |  Adobe PDF(3409Kb)  |  收藏  |  浏览/下载：72/13  |  提交时间：2024/05/09
melanin  precursor  lipid  ferroptosis  temperature change  anti-cold  COLD STRESS  PIGMENTATION  PEROXIDATION  MOUSE  
Study on alkaloids of endophytic Trichoderma atroviride B7 from Colquhounia coccinea var. mollis 期刊论文
Acta Pharmaceutica Sinica, 2023, 卷号: 58, 期号: 4, 页码: 963-966 0513-4870(2023)58:4<963:HBHNSZ>2.0.TX;2-8
作者:  Li Wenyuan;  Wang Ying;  Kuang Ce;  Guo Kai;  Liu Yan;  Li Shenghong
浏览  |  Adobe PDF(1092Kb)  |  收藏  |  浏览/下载：14/3  |  提交时间：2024/07/30
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
作者:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
收藏  |  浏览/下载：111/0  |  提交时间：2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant 'tree of life' 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 4, 页码: nwaa105
作者:  Zhang,Yongzeng;  Deng,Tao;  Sun,Lu;  Landis,Jacob B.;  Moore,Michael J.;  Wang,Hengchang;  Wang,Yuehua;  Hao,Xiaojiang;  Chen,Jijun;  Li,Shenghong;  Xu,Maonian;  Puno,Pema-Tenzin;  Raven,Peter H.;  Sun,Hang
收藏  |  浏览/下载：158/0  |  提交时间：2022/04/02
secondary metabolites  phylogenetic tree  phylogenetic signal  co-diversification  evolution  bioprospecting  seed plants  DIVERSIFICATION  EVOLUTION  DIVERSITY  SIGNAL  ANGIOSPERMS  CHEMISTRY  DEFENSES  FOSSIL  KEYS  
Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant 'tree of life' 期刊论文
NATIONAL SCIENCE REVIEW, 2021
作者:  Zhang,Yongzeng;  Deng,Tao;  Sun,Lu;  Landis,Jacob B.;  Moore,Michael J.;  Wang,Hengchang;  Wang,Yuehua;  Hao,Xiaojiang;  Chen,Jijun;  Li,Shenghong;  Xu,Maonian;  Puno,Pema-Tenzin;  Raven,Peter H.;  Sun,Hang
浏览  |  Adobe PDF(1313Kb)  |  收藏  |  浏览/下载：208/38  |  提交时间：2023/09/08
Antifeedant, cytotoxic, and anti-inflammatory neo-clerodane diterpenoids in the peltate glandular trichomes and fresh leaves of Ajuga forrestii 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 186, 页码: 112731
作者:  Wang,Ying;  Liu,Yan-Chun;  Li,Wen-Yuan;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(4803Kb)  |  收藏  |  浏览/下载：142/34  |  提交时间：2022/04/02
Ajuga forrestii Diels  Lamiaceae  Glandular trichomes  Laser microdissection  Diterpenoids  Defensive function  Antifeedant activity  Anti-inflammatory activity  Cytotoxicity  SESQUITERPENE LACTONES  PHYTOCHEMISTRY  CONSTITUENTS  DECUMBENS  HARBOR  PLANTS  L.