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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Ormosianines A-P, Structurally Diverse Quinolizidine Alkaloids with AChE Inhibitory Effects from Ormosia yunnanensis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2023, 卷号: 86, 期号: 9, 页码: 2193-2205
作者:  Jin,Qiong;  Qin,Xu-Jie;  Sun,Wen-Jie;  Ding,Xiao;  Zhao,Yun;  Wang,Chang-Bin;  Tao,Xing-Yu;  Luo,Xiao-Dong
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ACETYLCHOLINESTERASE  SEEDS  PLANTS  
Hepatic Stellate Celland Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis 期刊论文
ACS NANO, 2023, 卷号: 17, 期号: 23, 页码: 23608-23625
作者:  Niu,Xia;  Meng,Yanan;  Cui,Jinjin;  Li,Rui;  Ding,Xiao;  Niu,Bingyu;  Chang,Ge;  Xu,Ning;  Li,Guiling;  Wang,Yucheng;  Wang,Lulu
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liver fibrosis  dihydrotanshinone I  hepaticstellate cells  vitamin A  cyclodextrin  liver microbiome  STRATEGY  THERAPY  TARGET  NANOPARTICLES  PATHWAY  
Sesquiterpenes from Carpesium faberi triggered ROS-induced apoptosis and protective autophagy in hepatocellular carcinoma cells 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113805
作者:  Yan,Ying;  Chen,Jie;  Peng,Mingyou;  Zhang,Xiong;  Feng,Enming;  Li,Qindan;  Guo,Bing;  Ding,Xiao;  Zhang,Yu;  Tang,Lei
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Carpesium faberi (compositae)  Sesquiterpenes  Structural elucidation  Cytotoxic activities  Autophagy  LACTONE DIMERS  MYRRHANONE C  XANTHANOLIDES  TRITERPENE  HYBRIDS  ESTERS  
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 306, 页码: 116158
作者:  Guo,Hui-Hui;  Shen,Hao-Ran;  Tang,Ming-Ze;  Sheng,Ning;  Ding,Xiao;  Lin,Yuan;  Zhang,Jin-Lan;  Jiang,Jian-Dong;  Gao,Tian-Le;  Wang,Lu-Lu;  Han,Yan-Xing
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Dengzhan shengmai  Microbiota-gut-brain axis  Short-chain fatty acids  Cerebral ischemia  Gut barrier  Fecal microbiota transplantation  STROKE  SCUTELLARIN  
Acetylcholinesterase inhibitory activity of sesquiterpenoids isolated from Laggera pterodonta 期刊论文
FRONTIERS IN PLANT SCIENCE, 2023, 卷号: 14, 页码: 1074184
作者:  Li,Jinliang;  Li,Fengchao;  Wu,Guoxing;  Gui,Furong;  Li,Hongmei;  Xu,Lili;  Hao,Xiaojiang;  Zhao,Yuhan;  Ding,Xiao;  Qin,Xiaoping
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Laggera pterodonta  sesquiterpenes  acetylcholinesterase  enzyme kinetics  toxic effects  DERIVATIVES  FLAVONOIDS  TERPENOIDS  MECHANISM  
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1219362
作者:  Guo,Xiuping;  Li,Rui;  Cui,Jinjin;  Hu,Chujuan;  Yu,Haoyang;  Ren,Ling;  Cheng,Yangyang;  Jiang,Jiandong;  Ding,Xiao;  Wang,Lulu
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Erigeron Breviscapus Injection  Dengzhanxixin  Erigeron Breviscapus (Vant  ) Hand  -mazz  Colorectal Cancer  Necroptosis  Drug Resistance  Tumor-necrosis-factor  Colorectal-cancer  Natural Compounds  Scutellarin  Apoptosis  Proliferation  Macrophages  Migration  Invasion  Therapy  
Two new monoterpenoid indole alkaloids from the kernels of Kopsia arborea 期刊论文
NATURAL PRODUCT RESEARCH, 2023, 卷号: 37, 期号: 7, 页码: 1047-1052
作者:  Chen, Chen;  Ding, Xiao;  Han, Lingling;  Zhu, Wentao;  Huang, Kepu;  Hao, Xiaojiang;  Zhang, Yu
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Prebiotic-Based Nanoamorphous Atorvastatin Attenuates Nonalcoholic Fatty Liver Disease by Retrieving Gut and Liver Health 期刊论文
SMALL STRUCTURES, 2023, 页码: 2200312
作者:  Cui,Jin-Jin;  Li,Rui;  Ma,Xiao-Lei;  Yu,Hao-Yang;  Luo,Zhi-Gang;  Du,Peng;  Ren,Ling;  Ding,Xiao;  Guo,Xiu-Ping;  Zheng,Wen-Sheng;  Jiang,Jian-Dong;  Che,Yongsheng;  Wang,Lu-Lu
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atorvastatin  gut flora  nanoamorphous  nonalcoholic fatty liver disease  prebiotics  SOLID DISPERSIONS  STATIN USE  EFFICACY  STEATOHEPATITIS  FORMULATION  SAFETY  ABSORPTION  ACTIVATION  MICROBIOTA  CIRRHOSIS  
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023
作者:  Wang,Yin-Yuan;  Ni,Jian-Cheng;  Zhao,Yue-Qin;  Yang,Xu;  Niu,Zhen-Peng;  Yang,Xing-Zhi;  Dong,Xian-Xiang;  Zhao,Yu-Han;  Hao,Xiao-Jiang;  Ding,Xiao
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Iridoid glycosides  Morinda officinalis  lysosomal biogenesis  TFEB/TFE3  antioxidant activity  TRANSCRIPTIONAL CONTROL  TFEB  PHOSPHORYLATION  REVEALS  PATHWAY