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Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020
作者:  Li, Xue;  Kong, Lingmei;  Yang, Qihong;  Duan, Aizhu;  Ju, Xiaoman;  Cai, Bicheng;  Chen, Lin;  An, Tao;  Li, Yan
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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：299/76  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
作者:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
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Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
收藏  |  浏览/下载：455/0  |  提交时间：2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Structure and Function of the PriC DNA Replication Restart Protein 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 35, 页码: 18384-18396
作者:  Wessel, Sarah R.;  Cornilescu, Claudia C.;  Cornilescu, Gabriel;  Metz, Alice;  Leroux, Maxime;  Hu, Kaifeng;  Sandler, Steven J.;  Markley, John L.;  Keck, James L.
浏览  |  Adobe PDF(21213Kb)  |  收藏  |  浏览/下载：278/54  |  提交时间：2016/11/04
Dna Helicase  Dna Replication  Dna-protein Interaction  Nuclear Magnetic Resonance (Nmr)  Protein-protein Interaction  Dna Replication Restart  Dnab Helicase  Pric  Single-stranded Dna-binding Protein  
Natural Diterpenoid Compound Elevates Expression of Bim Protein, Which Interacts with Antiapoptotic Protein Bcl-2, Converting It to Proapoptotic Bax-like Molecule 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 2, 页码: 1054-1065
作者:  Zhao, Lixia;  He, Feng;  Liu, Haiyang;  Zhu, Yushan;  Tian, Weili;  Gao, Ping;  He, Hongping;  Yue, Wen;  Lei, Xiaobo;  Ni, Biyun;  Wang, Xiaohui;  Jin, Haijing;  Hao, Xiaojiang;  Lin, Jialing;  Chen, Quan
浏览  |  Adobe PDF(2908Kb)  |  收藏  |  浏览/下载：265/75  |  提交时间：2015/06/17
Baicalin, a Flavone, Induces the Differentiation of Cultured Osteoblasts AN ACTION VIA THE Wnt/beta-CATENIN SIGNALING PATHWAY 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 卷号: 286, 期号: 32, 页码: 27882-27893
作者:  Guo, Ava J. Y.;  Choi, Roy C. Y.;  Cheung, Anna W. H.;  Chen, Vicky P.;  Xu, Sherry L.;  Dong, Tina T. X.;  Chen, Ji J.;  Tsim, Karl W. K.
浏览  |  Adobe PDF(3035Kb)  |  收藏  |  浏览/下载：286/58  |  提交时间：2012/07/25
Hormone-replacement Therapy  Bone Loss  Postmenopausal Osteoporosis  Scutellaria-baicalensis  Heme Oxygenase-1  Gene-expression  Protein  Osteoprotegerin  Genistein  Cells  
Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 卷号: 284, 期号: 16, 页码: 10672-10683
作者:  Wang, Conan K.;  Hu, Shu-Hong;  Martin, Jennifer L.;  Sjogren, Tove;  Hajdu, Janos;  Bohlin, Lars;  Claeson, Per;  Goransson, Ulf;  Rosengren, K. Johan;  Tang, Jun;  Tan, Ning-Hua;  Craik, David J.
Adobe PDF(762Kb)  |  收藏  |  浏览/下载：274/81  |  提交时间：2012/03/21
Ligusticum Chuanxiong  4-pentylcyclohex-3-ene-1 Alpha  Phthalide Derivatives  2 Beta-diol  Ligusticoside a  Wallichii  Phthalides  Constituents  Derivatives  Rhizomes  Dimers  
Differential degradation of extraplastidic and plastidic lipids during freezing and post-freezing recovery in Arabidopsis thaliana 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 卷号: 283, 期号: 1, 页码: 461-468
作者:  Li, Weiqi;  Wang, Ruiping;  Li, Maoyin;  Li, Lixia;  Wang, Chuanming;  Welti, Ruth;  Wang, Xuemin
Adobe PDF(551Kb)  |  收藏  |  浏览/下载：404/117  |  提交时间：2012/06/12
Protonation of a Neutral (S)-β-Bisabolene Intermediate IsInvolved in (S)-β-Macrocarpene Formation by the MaizeSesquiterpene Synthases TPS6 and TPS11 期刊论文
THE JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 卷号: 283, 页码: 20779–20788
作者:  Tobias G. Kollner;  Christiane Schnee;  Shenghong Li;  Ales Svatos;  Bernd Schneider;  Jonathan Gershenzon;  Jorg Degenhardt
Adobe PDF(826Kb)  |  收藏  |  浏览/下载：100/1  |  提交时间：2017/07/19