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Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
浏览  |  Adobe PDF(13632Kb)  |  收藏  |  浏览/下载:313/33  |  提交时间:2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Adenanthin targets proteins involved in the regulation of disulphide bonds 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2014, 卷号: 89, 期号: 2, 页码: 210-216
作者:  Muchowicz, Angelika;  Firczuk, Malgorzata;  Chlebowska, Justyna;  Nowis, Dominika;  Stachura, Joanna;  Barankiewicz, Joanna;  Trzeciecka, Anna;  Klossowski, Szymon;  Ostaszewski, Ryszard;  Zagozdzon, Radoslaw;  Pu, Jian-Xin;  Sun, Han-Dong;  Golab, Jakub
Adobe PDF(1121Kb)  |  收藏  |  浏览/下载:469/60  |  提交时间:2014/06/23
Adenanthin  Cancer  Peroxiredoxin  Protein Disulphide Isomerase  Thioredoxin  
Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with beta-Catenin/TCF4 Interaction in Colorectal Cancer Cells 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 7, 页码: e68525
作者:  Li, Xingyao;  Pu, Jianxin;  Jiang, Shiyou;  Su, Jia;  Kong, Lingmei;  Mao, Bingyu;  Sun, Handong;  Li, Yan
浏览  |  Adobe PDF(1775Kb)  |  收藏  |  浏览/下载:566/99  |  提交时间:2013/10/16
Beta-catenin  Colon-cancer  Response Element  Activation  Expression  Pathway  Complex  Growth  Apc  Antagonists  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
Adobe PDF(2066Kb)  |  收藏  |  浏览/下载:293/63  |  提交时间:2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53  
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells 期刊论文
NATURE CHEMICAL BIOLOGY, 2012, 卷号: 8, 期号: 5, 页码: 486-493
作者:  Liu, Chuan-Xu;  Yin, Qian-Qian;  Zhou, Hu-Chen;  Wu, Ying-Li;  Pu, Jian-Xin;  Xia, Li;  Liu, Wei;  Huang, Xin;  Jiang, Tao;  Wu, Ming-Xuan;  He, Li-Cai;  Zhao, Ya-Xue;  Wang, Xiao-Lin;  Xiao, Wei-Lie;  Chen, Hong-Zhuan;  Zhao, Qian;  Zhou, Ai-Wu;  Wang, Li-Shun;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(1434Kb)  |  收藏  |  浏览/下载:677/197  |  提交时间:2012/06/07
Cimicifuga Foetida  Cycloartane  Cytotoxicity  Ranunculaceae  Breast-cancer Cells  Crude Drug Shoma  Racemosa Extract  Simplex Wormsk  Cyclolanostanol Xylosides  Triterpene Glycosides  Chemical-constituents  Prostate-cancer  Aerial Parts  Black Cohosh  
Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 5, 页码: e20159
作者:  Ma, Liang;  Wen, Zhe-Sheng;  Liu, Zi;  Hu, Zheng;  Ma, Jun;  Chen, Xiao-Qin;  Liu, Yong-Qiang;  Pu, Jian-Xin;  Xiao, Wei-Lie;  Sun, Han-Dong;  Zhou, Guang-Biao
Adobe PDF(634Kb)  |  收藏  |  浏览/下载:350/106  |  提交时间:2012/03/16
Gastric-cancer  Breast-cancer  Phospho-akt  Smoking  Cells  Carcinoma  Survival  Leukemia  China  
Electrospray tandem mass spectrometry of longipedlactone triterpenoids 期刊论文
JOURNAL OF MASS SPECTROMETRY, 2010, 卷号: 45, 期号: 4, 页码: 451-455
作者:  Wu, Zhi-Jun;  Pu, Jian-Xin;  Li, Li-Mei;  Fang, Dong-Mei;  Qi, Hua-Yi;  Chen, Jian-Zhong;  Li, Guo-You;  Sun, Han-Dong;  Zhang, Guo-Lin
Adobe PDF(193Kb)  |  收藏  |  浏览/下载:372/81  |  提交时间:2012/03/21
Onosma Paniculatum  Zicao  Cancer  Cell Cycle  Caspase-3  Traditional Chinese Medicine  Naphthoquinone Derivatives  Induced Apoptosis  Natural-products  Cancer-therapy  In-vitro  Shikonin  Dna  Pharmacogenomics  Induction  
Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus 期刊论文
PLANTA MEDICA, 1998, 卷号: 64, 期号: 8, 页码: 728-731
作者:  Qiu, SX;  Sun, HD;  Lobkovsky, E;  Chai, H;  Clardy, I;  Farnsworth, NR;  Pezzuto, JM;  Fong, HHS
浏览  |  Adobe PDF(312Kb)  |  收藏  |  浏览/下载:146/29  |  提交时间:2015/08/17
Isodon Megathyrsus  Labiatae  Leaves  Ent-kaurene Diterpene  Human Cancer Lines  Cytotoxic Activity  2d-nmr Techniques  X-ray Crystallography  Megathyrin b  Electrospray Lc/ms