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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：7/2  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：172/89  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Antitumor aporphine alkaloids from Thalictrum wangii 期刊论文
FITOTERAPIA, 2018, 卷号: 128, 页码: 213-217
作者:  Jin, Qiong;  Yang, Dong;  Dai, Zhi;  Khan, Afsar;  Wang, Bei;  Wei, Xin;  Sun, Ying;  Zhao, Yun-Li;  Wang, Yi-Fen;  Liu, Ya-Ping;  Zhao, Xu-Dong;  Luo, Xiao-Dong
收藏  |  浏览/下载：107/0  |  提交时间：2018/12/27
Cytotoxic Indole Alkaloid 3 alpha-Acetonyltabersonine Induces Glioblastoma Apoptosis via Inhibition of DNA Damage Repair 期刊论文
TOXINS, 2017, 卷号: 9, 期号: 5, 页码: 150
作者:  Li, Yuan;  Zhao, Yunli;  Zhou, Xia;  Ni, Wei;  Dai, Zhi;  Yang, Dong;  Hao, Junjun;  Luo, Lin;  Liu, Yaping;  Luo, Xiaodong;  Zhao, Xudong
浏览  |  Adobe PDF(3339Kb)  |  收藏  |  浏览/下载：218/50  |  提交时间：2017/07/31
Melodinus Suaveolens  Indole Alkaloid  3 Alpha-acetonyltabersonine  Glioblastoma  Cell Apoptosis  Dna Damage Repair