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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：295/65  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：214/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：446/205  |  提交时间：2017/02/28
Scopariusic Acid, a New Meroditerpenoid with a Unique Cyclobutane Ring Isolated from Isodon scoparius 期刊论文
ORGANIC LETTERS, 2013, 卷号: 15, 期号: 17, 页码: 4446-4449
作者:  Zhou, Min;  Zhang, Hai-Bo;  Wang, Wei-Guang;  Gong, Ning-Bo;  Zhan, Rui;  Li, Xiao-Nian;  Du, Xue;  Li, Li-Mei;  Li, Yan;  Lu, Yang;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(792Kb)  |  收藏  |  浏览/下载：431/111  |  提交时间：2014/01/21
2+2 Cycloadditions  Biyouyanagin-a  Biological Evaluation  Incarvillea-sinensis  Revised Structure  Skeleton  Littoralisone  Alkaloids  Diterpene  
Preventive and Therapeutic Effects of Adenanthin on Experimental Autoimmune Encephalomyelitis by Inhibiting NF-kappa B Signaling 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 191, 期号: 5, 页码: 2115-2125
作者:  Yin, Qian-Qian;  Liu, Chuan-Xu;  Wu, Ying-Li;  Wu, Shao-Fang;  Wang, Yan;  Zhang, Xia;  Hu, Xiao-Juan;  Pu, Jian-Xin;  Lu, Ying;  Zhou, Hu-Chen;  Wang, Hong-Lin;  Nie, Hong;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(2420Kb)  |  收藏  |  浏览/下载：348/45  |  提交时间：2013/10/16
Autoreactive T-cells  Multiple-sclerosis  Rheumatoid-arthritis  Glatiramer Acetate  Activation  Inflammation  System  Roles  Mice  Differentiation  
Rubesanolides A and B: Diterpenoids from Isodon rubescens 期刊论文
ORGANIC LETTERS, 2011, 卷号: 13, 期号: 6, 页码: 1406-1409
作者:  Zou, Juan;  Pan, Lutai;  Li, Qiji;  Zhao, Junhua;  Pu, Jianxin;  Yao, Ping;  Gong, Ningbo;  Lu, Yang;  Kondratyuk, Tamara P.;  Pezzuto, John M.;  Fong, Harry H. S.;  Zhang, Hongjie;  Sun, Handong
Adobe PDF(962Kb)  |  收藏  |  浏览/下载：387/135  |  提交时间：2012/04/10
Camellisins A-C, Three New Triterpenoids from the Roots of Camellia sinensis 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2010, 卷号: 58, 期号: 7, 页码: 939-943
作者:  Lei, Chun;  Hu, Zhuo;  Pu, Jian-Xin;  Wang, Yuan-Yuan;  Xiao, Wei-Lie;  Gong, Ning-Bo;  Li, Yan;  Lu, Yang;  Zheng, Qi-Tai;  Sun, Han-Dong
Adobe PDF(512Kb)  |  收藏  |  浏览/下载：373/106  |  提交时间：2012/03/21
Camellia Sinensis  Triterpenoid  Camellisin  
Chemical Constituents from the Leaves and Stems of Schisandra rubriflora 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2010, 卷号: 73, 期号: 2, 页码: 221-225
作者:  Wei-Lie Xiao;  Shi-Ying Yang;  Liu-Meng Yang;  Guang-Yu Yang;  Rui-Rui Wang;  Hai-Bo Zhang;  Wei Zhao;  Jian-Xin Pu;  Yang Lu;  Yong-Tang Zheng;  Han-Dong Sun
浏览  |  Adobe PDF(459Kb)  |  收藏  |  浏览/下载：217/24  |  提交时间：2012/03/21
Highly Oxygenated Nortriterpenoids  Anti-hiv Activity  Dibenzocyclooctadiene Lignans  Structure Elucidation  Chinensis  Schisanartane  Triterpenoids  Lancifolia  Micrantha  Acid  
Schilancidilactones A and B: two novel tetranortriterpenoids with an unprecedented skeleton from Schisandra lancifolia 期刊论文
TETRAHEDRON LETTERS, 2009, 卷号: 50, 期号: 43, 页码: 5962-5964
作者:  Luo, Xiao;  Chang, Ying;  Zhang, Xing-Jie;  Pu, Jian-Xin;  Gao, Xue-Mei;  Wu, Ying-Li;  Wang, Rui-Rui;  Xiao, Wei-Lie;  Zheng, Yong-Tang;  Lu, Yang;  Chen, Guo-Qiang;  Zheng, Qi-Tai;  Sun, Han-Dong
Adobe PDF(302Kb)  |  收藏  |  浏览/下载：367/119  |  提交时间：2012/03/21
Schisandra Lancifolia  Schilancidilactones a And b  Tetranortriterpenoid  Anti-hiv Activity  
Bioactive Nortriterpenoids from Schisandra grandiflora 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2009, 卷号: 72, 期号: 9, 页码: 1678-1681
作者:  Xiao, Wei-Lie;  Gong, Yan-Qing;  Wang, Rui-Rui;  Weng, Zhi-Ying;  Luo, Xiao;  Li, Xiao-Nian;  Yang, Guang-Yu;  He, Fei;  Pu, Jian-Xin;  Yang, Liu-Meng;  Zheng, Yong-Tang;  Lu, Yang;  Sun, Han-Dong
Adobe PDF(426Kb)  |  收藏  |  浏览/下载：308/93  |  提交时间：2012/03/21
Calycinum  Skeleton  Longeracemosum  Cascade