Chemical Constituents from the Leaves and Stems of Schisandra rubriflora

doi:10.1021/np900849y

	Chemical Constituents from the Leaves and Stems of Schisandra rubriflora
	Wei-Lie Xiao; Shi-Ying Yang; Liu-Meng Yang; Guang-Yu Yang; Rui-Rui Wang; Hai-Bo Zhang; Wei Zhao; Jian-Xin Pu; Yang Lu; Yong-Tang Zheng; Han-Dong Sun
	2010-02-01
发表期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
卷号	73 期号:2 页码:221-225
摘要	Six new nortriterpenoids, schirubridilactones A-F (1-6). as well as 14 known compounds, were isolated from the leaves and stems of Schisandra rubriflora. The Structures of 1-6 were elucidated oil the basis of spectroscopic methods including HSQC, HMBC, (1)H-(1)H COSY, and ROESY NMR experiments. The relative stereochemistry of I was confirmed through single-crystal X-ray analysis. In addition, compounds 1-6 showed anti-HIV-1 activity with EC(50) values in the range 14.3-80.8 mu g/mL and Selectivity indices in the range 2.2-9.0.
关键词	Highly Oxygenated Nortriterpenoids Anti-hiv Activity Dibenzocyclooctadiene Lignans Structure Elucidation Chinensis Schisanartane Triterpenoids Lancifolia Micrantha Acid
学科领域	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI	10.1021/np900849y
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000274803600025
引用统计	被引频次：29[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4226
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Wei-Lie Xiao,Shi-Ying Yang,Liu-Meng Yang,et al. Chemical Constituents from the Leaves and Stems of Schisandra rubriflora[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(2):221-225.
APA	Wei-Lie Xiao.,Shi-Ying Yang.,Liu-Meng Yang.,Guang-Yu Yang.,Rui-Rui Wang.,...&Han-Dong Sun.(2010).Chemical Constituents from the Leaves and Stems of Schisandra rubriflora.JOURNAL OF NATURAL PRODUCTS,73(2),221-225.
MLA	Wei-Lie Xiao,et al."Chemical Constituents from the Leaves and Stems of Schisandra rubriflora".JOURNAL OF NATURAL PRODUCTS 73.2(2010):221-225.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
np900849y.pdf（459KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	浏览下载