Rubesanolides A and B: Diterpenoids from Isodon rubescens
Zou, Juan1,2; Pan, Lutai1; Li, Qiji1; Zhao, Junhua1; Pu, Jianxin2; Yao, Ping3; Gong, Ningbo4; Lu, Yang4; Kondratyuk, Tamara P.5; Pezzuto, John M.5; Fong, Harry H. S.3; Zhang, Hongjie3; Sun, Handong2
通讯作者Pan, LT (reprint author), Guiyang Coll Tradit Chinese Med, Guiyang 550002, Guizhou, Peoples R China
2011-03-18
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号13期号:6页码:1406-1409
摘要From the medicinal plant Isodon rubescens, we isolated two novel diterpenes, rubesanolides A (1) and B (2). The compounds contain a unique beta-lactone subgroup. This is the first discovery for a natural diterpene having rings A, B, and C In chair, boat, and twist-chair conformations, respectively. The structures were elucidated by analysis of spectroscopic data, and the absolute configuration of 1 was determined by X-ray diffraction.
学科领域Chemistry
DOI10.1021/ol200086k
收录类别SCI ; IC
语种英语
WOS记录号WOS:000288148800036
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5399
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Guiyang Coll Tradit Chinese Med, Guiyang 550002, Guizhou, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Univ Illinois, Program Collaborat Res Pharmaceut Sci, Dept Med Chem & Pharmacognosy, Coll Pharm, Chicago, IL 60612 USA
4.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
5.Univ Hawaii, Coll Pharm, Hilo, HI 96720 USA
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Zou, Juan,Pan, Lutai,Li, Qiji,et al. Rubesanolides A and B: Diterpenoids from Isodon rubescens[J]. ORGANIC LETTERS,2011,13(6):1406-1409.
APA Zou, Juan.,Pan, Lutai.,Li, Qiji.,Zhao, Junhua.,Pu, Jianxin.,...&Sun, Handong.(2011).Rubesanolides A and B: Diterpenoids from Isodon rubescens.ORGANIC LETTERS,13(6),1406-1409.
MLA Zou, Juan,et al."Rubesanolides A and B: Diterpenoids from Isodon rubescens".ORGANIC LETTERS 13.6(2011):1406-1409.
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