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RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
作者:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
浏览  |  Adobe PDF(9639Kb)  |  收藏  |  浏览/下载:157/30  |  提交时间:2019/07/29
RA-XII  lipogenesis  SCAP  SREBP  liver cancer  
Redox Dual-Responsive and O-2-Evolving Theranostic Nanosystem for Highly Selective Chemotherapy against Hypoxic Tumors 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 90-103
作者:  Chen, Huachao;  Li, Fei;  Yao, Yongrong;  Wang, Zhe;  Zhang, Zhihao;  Tan, Ninghua
浏览  |  Adobe PDF(3409Kb)  |  收藏  |  浏览/下载:208/55  |  提交时间:2019/07/29
cancer  theranostic system  hypoxic tumor  ROS/GSH dual-activatable  cyclopeptide RA-V  fluorescence imaging  
Systematic characterization and quantification of Rubiaceae-type cyclopeptides in 20 Rubia species by ultra performance liquid chromatography tandem mass spectrometry combined with chemometrics 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1581, 页码: 43-54
作者:  Zhang, Xuejia;  Bi, Qirui;  Wu, Xingdong;  Wang, Zhe;  Miao, Yuanyuan;  Tan, Ninghua
收藏  |  浏览/下载:81/0  |  提交时间:2019/03/29
Rubiaceae-type cyclopeptides  Rubia  UPLC-QqQ-MS/MS  Multiple reaction monitoring  Chemometric approach  Chemotaxonomy  
NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 220, 页码: 220-227
作者:  Zeng, Guang-Zhi;  Wang, Zhe;  Zhao, Li-Mei;  Fan, Jun-Ting;  Tan, Ning-Hua
收藏  |  浏览/下载:210/0  |  提交时间:2018/07/16
Rubiarbonol g  Rubia Yunnanensis  Cytotoxicity  Mechanism  
Nematicidal quinone derivatives from three & IT;Rubia & IT; plants 期刊论文
TETRAHEDRON, 2018, 卷号: 74, 期号: 17, 页码: 2115-2120
作者:  Zhao, Si-Meng;  Kuang, Bin;  Zeng, Guang-Zhi;  Wang, Zhe;  Wang, Jia;  Chen, Xiao-Qiang;  Tan, Ning-Hua
浏览  |  Adobe PDF(696Kb)  |  收藏  |  浏览/下载:230/38  |  提交时间:2018/05/31
Rubia  Rubia Alata  Rubia Wallichiana  Rubia Schumanniana  Quinones  Nematicidal Activity  
Natural cyclopeptide RA-V inhibits the NF-kappa B signaling pathway by targeting TAK1 期刊论文
CELL DEATH & DISEASE, 2018, 卷号: 9, 页码: 715
作者:  Wang, Zhe;  Zhao, Simeng;  Song, Lihua;  Pu, Yuzhi;  Wang, Qiang;  Zeng, Guangzhi;  Liu, Xing;  Bai, Ming;  Li, Shao;  Gao, Fabao;  Chen, Lijuan;  Wang, Chen;  Tan, Ninghua
收藏  |  浏览/下载:88/0  |  提交时间:2019/03/29
Rubipodanones A-D, naphthohydroquinone dimers from rhizomes of &ITRubia podantha &IT 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 145, 页码: 153-160
作者:  Wang, Zhe;  Zhao, Si-Meng;  Hu, Yan-Yun;  Feng, Li;  Zhao, Li-Mei;  Di, Ying-Tong;  Tan, Ning-Hua
浏览  |  Adobe PDF(1384Kb)  |  收藏  |  浏览/下载:245/51  |  提交时间:2018/05/08
Rubia Podantha  Rubiaceae  Naphthohydroquinone Dimers  Rubipodanones A-d  Cytotoxicity  Nf-kappa b Signaling Pathway  
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
作者:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
浏览  |  Adobe PDF(4110Kb)  |  收藏  |  浏览/下载:155/37  |  提交时间:2018/05/08
Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
柄花茜草化学与活性及茜草科类型环肽抗肿瘤机制研究 学位论文
, 昆明: 中国科学院大学, 2016
作者:  汪哲
Adobe PDF(11254Kb)  |  收藏  |  浏览/下载:168/13  |  提交时间:2018/08/23
Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 52, 页码: 9673-9678
作者:  Chen, Xiao-Qiang;  Zhao, Si-Meng;  Wang, Zhe;  Zeng, Guang-Zhi;  Huang, Mao-Bo;  Tan, Ning-Hua
浏览  |  Adobe PDF(1412Kb)  |  收藏  |  浏览/下载:704/146  |  提交时间:2016/02/01
Rubia Cordifolia  Rubicordins A-c  Cyclopeptides  Cytotoxicity  Nf-kappa b Signaling Pathway