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Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N-9-Methyl Group in the Conformation and Bioactivity 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 12
作者:  Wang, Zhe;  Zhao, Si-Meng;  Zhao, Li-Mei;  Chen, Xiao-Qiang;  Zeng, Guang-Zhi;  Tan, Ning-Hua
浏览  |  Adobe PDF(805Kb)  |  收藏  |  浏览/下载:698/183  |  提交时间:2016/02/01
Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 40, 页码: 42704-42716
作者:  Luo, Xiangjian;  Yang, Lifang;  Xiao, Lanbo;  Xia, Xiaofeng;  Dong, Xin;  Zhong, Juanfang;  Liu, Ying;  Li, Namei;  Chen, Ling;  Li, Hongde;  Li, Wei;  Liu, Wenbin;  Yu, Xinfang;  Chen, Hanyong;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Bode, Ann;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
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Grifolin  Erk1/2  Dnmt1  Metastasis  
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载:185/30  |  提交时间:2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Leung,Hoi-Wing;  Zhao,Si-Meng;  Yue,Grace Gar-Lee;  Lee,Julia Kin-Ming;  Fung,Kwok-Pui;  Leung,Ping-Chung;  Tan,Ning-Hua;  Lau,Clara Bik-San
浏览  |  Adobe PDF(2369Kb)  |  收藏  |  浏览/下载:196/51  |  提交时间:2016/01/19
Gene Expression and Correlation of Pten and Fabp4 in Liver, Muscle, and Adipose Tissues of Type 2 Diabetes Rats 期刊论文
MEDICAL SCIENCE MONITOR, 2015, 卷号: 21, 期号: 8, 页码: 3616-3621
作者:  Su,Di;  Zhang,Chuan-ling;  Gao,Ying-chun;  Liu,Xiao-ying;  Li,Cai-ping;  Jian Huangfu;  Xiao,Rui
浏览  |  Adobe PDF(265Kb)  |  收藏  |  浏览/下载:153/49  |  提交时间:2016/01/19
Fatty Acid-binding Proteins  Diabetes Mellitus  Pten Phosphohydrolase  Type 2  
Fibulin-3 is a novel TGF-beta pathway inhibitor in the breast cancer microenvironment 期刊论文
ONCOGENE, 2015, 卷号: 34, 期号: 45, 页码: 5635-5647
作者:  Tian,H.;  Liu,J.;  Chen,J.;  Gatza,M. L.;  Blobe,G. C.
浏览  |  Adobe PDF(7351Kb)  |  收藏  |  浏览/下载:128/37  |  提交时间:2016/01/19
Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 33, 页码: 34953-34967
作者:  Liu,Yong-Qiang;  Wang,Xiao-Lu;  Cheng,Xin;  Lu,Yong-Zhi;  Wang,Gui-Zhen;  Li,Xin-Chun;  Zhang,Jian;  Wen,Zhe-Sheng;  Huang,Zhi-Liang;  Gao,Qin-Lei;  Yang,Li-Na;  Cheng,Yong-Xian;  Tao,Sheng-Ce;  Liu,Jinsong;  Zhou,Guang-Biao
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Skp1  Lung Cancer  Structure-based High-throughput Virtual Screening  Inhibitors  6-o-angeloylplenolin  
Penicamedine A, a Highly Oxygenated Hexacyclic Indole Alkaloid from Penicillium camemberti 期刊论文
CHEMISTRY & BIODIVERSITY, 2015, 卷号: 12, 期号: 10, 页码: 1547-1553
作者:  Zhu,Hucheng;  Chen,Chunmei;  Wang,Jianping;  Li,Xiao-Nian;  Wei,Guangzheng;  Guo,Yi;  Yao,Guangmin;  Luo,Zengwei;  Zhang,Jinwen;  Xue,Yongbo;  Zhang,Yonghui
浏览  |  Adobe PDF(686Kb)  |  收藏  |  浏览/下载:137/52  |  提交时间:2016/01/19
Anti-hiv Activity  Cytotoxic Activity  Indole Alkaloids  Penicamedine a  Penicillium Camemberti  X-ray Crystallography  
Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase 期刊论文
MICROBIAL CELL FACTORIES, 2015, 卷号: 14
作者:  Zhang,Ji;  Yan,Yi-Jun;  An,Jing;  Huang,Sheng-Xiong;  Wang,Xiang-Jing;  Xiang,Wen-Sheng
Adobe PDF(1508Kb)  |  收藏  |  浏览/下载:149/29  |  提交时间:2016/01/19
25-ethyl Ivermectin  25-methyl Ivermectin  Domain Swap  Insecticidal Activity  
Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Guo,Ao;  He,Dongming;  Xu,Hong-Bo;  Geng,Chang-An;  Zhao,Jian
浏览  |  Adobe PDF(1243Kb)  |  收藏  |  浏览/下载:152/59  |  提交时间:2016/01/19