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Structural Revisions of a Class of Natural Products: Scaffolds of Aglycon Analogues of Fusicoccins and Cotylenins Isolated from Fungi 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 12, 页码: 4069-4073
作者:  Tang, Ying;  Xue, Yongbo;  Du, Guang;  Wang, Jianping;  Liu, Junjun;  Sun, Bin;  Li, Xiao-Nian;  Yao, Guangmin;  Luo, Zengwei;  Zhang, Yonghui
Adobe PDF(704Kb)  |  收藏  |  浏览/下载：373/100  |  提交时间：2016/08/22
Computational Chemistry  Natural Products  Nmr Spectroscopy  Structure Elucidation  Terpenoids  
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：310/73  |  提交时间：2016/06/27
Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：334/75  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Indole Alkaloids with New Skeleton Activating Neural Stem Cells 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 21, 页码: 5808-5811
作者:  Yang, Xing-Wei;  Yang, Cui-Ping;  Jiang, Li-Ping;  Qin, Xu-Jie;  Liu, Ya-Ping;  Shen, Qiu-Shuo;  Chen, Yong-Bin;  Luo, Xiao-Dong
Adobe PDF(312Kb)  |  收藏  |  浏览/下载：414/82  |  提交时间：2015/01/20
Enigmatic Relationships  Bayesian Phylogenetics  Evolutionary History  C-4 Photosynthesis  Plastid Genomes  Grasses Poaceae  Tree Selection  Woody Bamboos  Mixed Models  Nuclear Loci  Branch Length  Chloroplast Phylogenomics  Data Partitioning  Low Sequence Divergence  Sampling  Temperate Woody Bamboos  
(+/-)-Aspongamide A, an N-Acetyldopamine Trimer Isolated from the Insect Aspongopus chinensis, Is an Inhibitor of p-Smad3 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 2, 页码: 532-535
作者:  Yan, Yong-Ming;  Ai, Jun;  Shi, Yan-Ni;  Zuo, Zhi-Li;  Hou, Bo;  Luo, Jie;  Cheng, Yong-Xian
Adobe PDF(229Kb)  |  收藏  |  浏览/下载：441/74  |  提交时间：2014/04/09
Disease  Products  
Lingzhiols, Unprecedented Rotary Door-Shaped Meroterpenoids as Potent and Selective Inhibitors of p-Smad3 from Ganoderma lucidum 期刊论文
ORGANIC LETTERS, 2013, 卷号: 15, 期号: 21, 页码: 5488-5491
作者:  Yan, Yong-Ming;  Ai, Jun;  Zhou, Li-Li;  Chung, Arthur C. K.;  Li, Rong;  Nie, Jing;  Fang, Ping;  Wang, Xin-Long;  Luo, Jie;  Hu, Qun;  Hou, Fan-Fan;  Cheng, Yong-Xian
Adobe PDF(299Kb)  |  收藏  |  浏览/下载：638/133  |  提交时间：2014/01/13
Diabetic-nephropathy  High-glucose  Mesangial Cells  Up-regulation  Expression  Activation  Pathways  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
浏览  |  Adobe PDF(531Kb)  |  收藏  |  浏览/下载：311/65  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Sesquiterpenoids from Incarvillea arguta: Absolute Configuration and Biological Evaluation 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2012, 卷号: 75, 期号: 6, 页码: 1025-1029
作者:  Yan, Yong-Ming;  Wu, Gui-Sheng;  Dong, Xiao-Ping;  Shen, Lan;  Li, Yan;  Su, Jia;  Luo, Huai-Rong;  Zhu, Hua-Jie;  Cheng, Yong-Xian
Adobe PDF(283Kb)  |  收藏  |  浏览/下载：286/50  |  提交时间：2014/04/02
Electronic Circular-dichroism  Optical-rotation  Chemistry  Assay  
A Pair of Windmill-Shaped Enantiomers from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity 期刊论文
ORGANIC LETTERS, 2010, 卷号: 12, 期号: 14, 页码: 3196-3199
作者:  Wang, Fei;  Gao, Yuan;  Zhang, Ling;  Bai, Bing;  Hu, Ya Nan;  Dong, Ze Jun;  Zhai, Qi Wei;  Zhu, Hua Jie;  Liu, Ji Kai
Adobe PDF(185Kb)  |  收藏  |  浏览/下载：311/89  |  提交时间：2012/03/21
Sesquiterpene Lactones  Optical-rotation  Water Extract  Strychnifolia  Root  Butanolides  
Cytotoxic ent-kaurane diterpenoids from Isodon sinuolata 期刊论文
PHYTOCHEMISTRY, 2009, 卷号: 70, 期号: 11-12, 页码: 1462-1466
作者:  He, Fei;  Xiao, Wei-Lie;  Pu, Jian-Xin;  Wu, Ying-Li;  Zhang, Hai-Bo;  Li, Xiao-Nian;  Zhao, Yong;  Yang, Li-Bin;  Chen, Guo-Qiang;  Sun, Han-Dong
Adobe PDF(297Kb)  |  收藏  |  浏览/下载：309/101  |  提交时间：2012/03/21
Isodon Sinuolata  Labiatae  Diterpenoids  Cytotoxicity