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Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：326/77  |  提交时间：2016/06/27
LC-MS-Guided Isolation of Penicilfuranone A: A New Antifibrotic Furancarboxylic Acid from the Plant Endophytic Fungus Penicillium sp sh18 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 149-155
作者:  Wang, Wei-Guang;  Li, Ao;  Yan, Bing-Chao;  Niu, Shu-Bin;  Tang, Jian-Wei;  Li, Xiao-Nian;  Du, Xue;  Challis, Gregory L.;  Che, Yongsheng;  Sung, Han-Dong;  Pu, Jian-Xin
浏览  |  Adobe PDF(3283Kb)  |  收藏  |  浏览/下载：369/86  |  提交时间：2016/06/27
Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：355/84  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Carboxymethyl- and Carboxyl-Catechins from Ripe Pu-er Tea 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 卷号: 62, 期号: 50, 页码: 12229-12234
作者:  Tian, Li-Wen;  Tao, Mu-Ke;  Xu, Min;  Hu, Jing;  Zhu, Hong-Tao;  Xiong, Wen-Yong;  Wang, Dong;  Yang, Chong-Ren;  Zhang, Ying-Jun
浏览  |  Adobe PDF(473Kb)  |  收藏  |  浏览/下载：399/102  |  提交时间：2015/06/17
Ripe  Pu-er Tea  Carboxymethyl Catechins  Carboxylcatechins  Insulin Sensitivity Activity  
Indole Alkaloids with New Skeleton Activating Neural Stem Cells 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 21, 页码: 5808-5811
作者:  Yang, Xing-Wei;  Yang, Cui-Ping;  Jiang, Li-Ping;  Qin, Xu-Jie;  Liu, Ya-Ping;  Shen, Qiu-Shuo;  Chen, Yong-Bin;  Luo, Xiao-Dong
浏览  |  Adobe PDF(312Kb)  |  收藏  |  浏览/下载：435/88  |  提交时间：2015/01/20
Enigmatic Relationships  Bayesian Phylogenetics  Evolutionary History  C-4 Photosynthesis  Plastid Genomes  Grasses Poaceae  Tree Selection  Woody Bamboos  Mixed Models  Nuclear Loci  Branch Length  Chloroplast Phylogenomics  Data Partitioning  Low Sequence Divergence  Sampling  Temperate Woody Bamboos  
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1562Kb)  |  收藏  |  浏览/下载：314/51  |  提交时间：2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
Eudesmanolides from Wedelia trilobata (L.) Hitchc. as Potential Inducers of Plant Systemic Acquired Resistance 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2013, 卷号: 61, 期号: 16, 页码: 3884-3890
作者:  Li, Yating;  Hao, Xiaojiang;  Li, Shifei;  He, Hongping;  Yan, Xiaohui;  Chen, Yongdui;  Dong, Jiahong;  Zhang, Zhongkai;  Li, Shunlin
浏览  |  Adobe PDF(305Kb)  |  收藏  |  浏览/下载：730/136  |  提交时间：2013/06/08
Eudesmanolides  WedeL.a TriL.bata (L.) Hitchc.  Tobacco Mosaic Virus  Systemic Acquired Resistance  
Chemical Constituents from Chirita longgangensis var. hongyao with Inhibitory Activity against Porcine Respiratory and Reproductive Syndrome Virus 期刊论文
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2012, 卷号: 23, 期号: 10, 页码: 1925-1932
作者:  Su, Yao;  Bi, Jun-Long;  Wang, Yue-Hu;  Tan, Ying;  Yang, Jun;  Liu, Hong-Xin;  Gu, Wei;  Yin, Ge-Fen;  Long, Chun-Lin
浏览  |  Adobe PDF(809Kb)  |  收藏  |  浏览/下载：563/99  |  提交时间：2013/01/22
Gesneriaceae  Quinines  Porcine Reproductive And Respiratory Syndrome Virus  Chirita Longgangensis Var. Hongyao  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(719Kb)  |  收藏  |  浏览/下载：444/143  |  提交时间：2012/11/30
Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：371/96  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships