Carboxymethyl- and Carboxyl-Catechins from Ripe Pu-er Tea
Tian, Li-Wen1; Tao, Mu-Ke1,2; Xu, Min1; Hu, Jing1; Zhu, Hong-Tao1; Xiong, Wen-Yong1; Wang, Dong1; Yang, Chong-Ren1; Zhang, Ying-Jun1
AbstractRipe Pu-er tea, a special microbial postfermented tea originated from Yunnan Province, China, since ancient times, is made from green Pu-er tea prepared from the leaves of Camellia sinensis var. assamica (Theaceae). Chemical investigation on thearubigin (n-BuOH-soluble) fraction of the commercial ripe Pu-er tea, led to the identification of four new flavan-3-ol derivatives, 8-carboxymethyl-(+)-catechin (1), 8-carboxymethyl-(+)-catechin methyl ester (2), 6-carboxymethyl-(+)-catechin (3), and 6-carboxyl-(-)-gallocatechin (4), together with 18 known compounds, including other three flavan-3-ol derivatives (5-7), 10 flavonoid glycosides (8-17), two hydrolyzable tannins (18 and 19), two quinic acid derivatives (20-21), and a purine alkaloid (22). Flavonoid glycosides 8-11 are reported from tea plants for the first time. The thearubigin fraction of ripe Pu-er tea was qualitatively analyzed by HPLC, and gallic acid was found to be the major component. Compounds 4, 6-17, 21 and 22 were tested for their acute activities on insulin sensitivity in differentiated 3T3-L1 adipocytes, but none of them showed significant bioactivity at a concentration of 10 mu M.
KeywordRipe Pu-er Tea Carboxymethyl Catechins Carboxylcatechins Insulin Sensitivity Activity
Indexed BySCI ; IC
WOS IDWOS:000346682100020
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Cited Times:21[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Chongqing Inst Food & Drug Control, Chongqing 401121, Peoples R China
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GB/T 7714
Tian, Li-Wen,Tao, Mu-Ke,Xu, Min,et al. Carboxymethyl- and Carboxyl-Catechins from Ripe Pu-er Tea[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2014,62(50):12229-12234.
APA Tian, Li-Wen.,Tao, Mu-Ke.,Xu, Min.,Hu, Jing.,Zhu, Hong-Tao.,...&Zhang, Ying-Jun.(2014).Carboxymethyl- and Carboxyl-Catechins from Ripe Pu-er Tea.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,62(50),12229-12234.
MLA Tian, Li-Wen,et al."Carboxymethyl- and Carboxyl-Catechins from Ripe Pu-er Tea".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 62.50(2014):12229-12234.
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