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B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
Authors:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
Favorite  |  View/Download:4/0  |  Submit date:2019/06/24
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
Authors:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Favorite  |  View/Download:87/0  |  Submit date:2019/03/18
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
Authors:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
View  |  Adobe PDF(500Kb)  |  Favorite  |  View/Download:146/50  |  Submit date:2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Enantioselective N-Heterocyclic Carbene-Catalyzed Synthesis of Spirocyclic Oxindole-benzofuroazepinones 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 24, 页码: 15225-15235
Authors:  Gao, Zhong-Hua;  Chen, Kun-Quan;  Zhang, Yan;  Kong, Ling-Mei;  Li, Yan;  Ye, Song
Favorite  |  View/Download:75/0  |  Submit date:2019/03/18
Synthesis and anti-proliferative activity of allogibberic acid derivatives containing 1,2,3-triazole pharmacophore 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2543-2549
Authors:  Wu, Ming-Jiang;  Wu, Dong-Mei;  Chen, Jing-Bo;  Zhao, Jing-Feng;  Gong, Liang;  Gong, Ya-Xiao;  Li, Yan;  Yang, Xiao-Dong;  Zhang, Hongbin
Favorite  |  View/Download:57/0  |  Submit date:2019/03/29
Click Glycosylation for the Synthesis of 1,2,3-Triazole-Linked Picropodophyllotoxin Glycoconjugates and Their Anticancer Activity 期刊论文
CHEMISTRYSELECT, 2017, 卷号: 2, 期号: 18, 页码: 5038-5044
Authors:  Zi, Cheng-Ting;  Yang, Liu;  Gao, Wei;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Hu, Jiang-Miao;  Jiang, Zi-Hua
View  |  Adobe PDF(3775Kb)  |  Favorite  |  View/Download:70/9  |  Submit date:2017/10/23
Anticancer Activity  Cu(i)-catalyzed Click Reaction  Glycoconjugates  Picropodophyllotoxin  Podophyllotoxin  
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 14, 页码: 3911-3914
Authors:  Wang, Li;  Yang, Jing;  Kong, Ling-Mei;  Deng, Jun;  Xiong, Zijun;  Huang, Jianping;  Luo, Jianping;  Yan, Yijun;  Hu, Yikao;  Li, Xiao-Nian;  Li, Yan;  Zhao, Yong;  Huang, Sheng-Xiong
View  |  Adobe PDF(1338Kb)  |  Favorite  |  View/Download:103/21  |  Submit date:2017/10/23
Protein-kinase-c  Phorbol Esters  Biological Evaluation  Biosynthesis  (+)-phorbol  Analogs  Cancer  Seeds  
Synthesis and Cytotoxic Activity of Novel Hybrid Compounds between Indolo[b]tetrahydrofuran and Imidazolium Salts 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 6, 页码: 1506-1515
Authors:  Liu Zhengfen;  Zhang Chaobo;  Duan Shengzu;  Liu Yang;  Chen Wen;  Li Yan;  Zhang Hongbin;  Yang Xiaodong
View  |  Adobe PDF(1186Kb)  |  Favorite  |  View/Download:48/14  |  Submit date:2017/10/23
Indolo[b]Tetrahydrofuran  Imidazolium Salts  Hybrid Compound  Cytotoxic Activity  
Lanostane-type triterpenoids from Kadsura coccinea 期刊论文
TETRAHEDRON, 2017, 卷号: 73, 期号: 20, 页码: 2931-2937
Authors:  Hu, Zheng-Xi;  Li, Xiao-Nian;  Shi, Yi-Ming;  Wang, Wei-Guang;  Du, Xue;  Li, Yan;  Zhang, Yong-Hui;  Pu, Jian-Xin;  Sun, Han-Dong
View  |  Adobe PDF(860Kb)  |  Favorite  |  View/Download:520/92  |  Submit date:2017/07/10
Kadsura Coccinea  Lanostane-type Triterpenoids  Cytotoxicity  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
Authors:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
View  |  Adobe PDF(3138Kb)  |  Favorite  |  View/Download:602/86  |  Submit date:2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer