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PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
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mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
Authors:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
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Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
Authors:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
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FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
Authors:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
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SKELETONS  
Balance scientific and ethical concerns to achieve a nuanced perspective on 'blood amber' 期刊论文
NATURE ECOLOGY & EVOLUTION, 2021, 卷号: 5, 期号: 6, 页码: 705-706
Authors:  Shi,Chao;  Cai,Hao-hong;  Jiang,Ri-xin;  Wang,Shuo;  Engel,Michael S.;  Yuan,Ji;  Bai,Ming;  Yang,Ding;  Long,Chun-lin;  Zhao,Zun-tian;  Zhang,Dian-xiang;  Zhang,Xian-chun;  Peng,Hua;  Wang,Yong-dong;  Spicer,Robert A.
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Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
Authors:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
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Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
Authors:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
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Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Microplastics as an emerging threat to plant and soil health in agroecosystems 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 787, 页码: 147444
Authors:  Zhou,Jie;  Wen,Yuan;  Marshall,Miles R.;  Zhao,Jie;  Gui,Heng;  Yang,Yadong;  Zeng,Zhaohai;  Jones,Davey L.;  Zang,Huadong
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Microplastics  Plant growth  Soil carbon storage  Nutrient cycling  Greenhouse gas emissions  Biodegradable plastics  Agroecosystem  POLYSTYRENE LATEX NANOPARTICLES  ORGANIC-MATTER  PLASTIC MULCH  FILM RESIDUES  CARBON  NITRIFICATION  MECHANISMS  CYTOTOXICITY  NANOPLASTICS  EMISSIONS  
C-19 Benzylisoquinoline Alkaloid with Unprecedented Architecture from Hypecoum erectum 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 23, 页码: 16764-16769
Authors:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Hu,Kun;  He,Ying-Jie;  Yang,Xing-Wei;  Luo,Xiao-Dong
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OPIUM POPPY  BIOSYNTHESIS  APORPHINE  TETRANDRINE  PAPAVERINE  DISCOVERY  
A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 271, 页码: 113830
Authors:  Zhou,Ying;  He,Ying-Jie;  Wang,Zhao-Jie;  Hu,Bin-Yuan;  Xie,Tian-Zhen;  Xiao,Xia;  Zhou,Zhong-Shun;  Sang,Xu-Yan;  Luo,Xiao-Dong
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Glechoma  Plant characteristics  Phytochemistry  Ethnobotanical uses  Pharmacological activities