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Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
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Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
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mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
High quality genome of Erigeron breviscapus provides a reference for herbal plants in Asteraceae 期刊论文
MOLECULAR ECOLOGY RESOURCES, 2021, 卷号: 21, 期号: 1, 页码: 153-169
Authors:  He,Simei;  Dong,Xiao;  Zhang,Guanghui;  Fan,Wei;  Duan,Shengchang;  Shi,Hong;  Li,Dawei;  Li,Rui;  Chen,Geng;  Long,Guangqiang;  Zhao,Yan;  Chen,Mo;  Yan,Mi;  Yang,Jianli;  Lu,Yingchun;  Zhou,Yanli;  Chen,Wei;  Dong,Yang;  Yang,Shengchao
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Erigeron breviscapus  genome  GWAS  scutellarin  FLAVONOIDS-BIOSYNTHESIS  WIDE ASSOCIATION  AGRONOMIC TRAITS  HIGH-ACCURACY  GENE FAMILY  PREDICTION  ALIGNMENT  PATHWAY  IDENTIFICATION  ACCUMULATION  
(-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 23, 页码: 12859-12867
Authors:  Yan,Bing-Chao;  Zhou,Min;  Li,Jian;  Li,Xiao-Nian;  He,Shi-Jun;  Zuo,Jian-Ping;  Sun,Han-Dong;  Li,Ang;  Puno,Pema-Tenzin
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bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation  
Comparison of chemical constituents in diverse zanthoxylum herbs, and evaluation of their relative antibacterial and nematicidal activity 期刊论文
FOOD BIOSCIENCE, 2021, 卷号: 42, 页码: 101206
Authors:  Wang,Zhao-Jie;  Zhou,Ying;  Shi,Xiao-Long;  Xia,Xiao;  He,Ying-Jie;  Zhu,Yan-Yan;  Xie,Tian-Zhen;  Liu,Tie;  Xu,Xiang-Juan;  Luo,Xiao-Dong
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Zanthoxylum herbs  Antibacterial  Nematicidal  Mass spectrometry  BUNGEANUM MAXIM.  LIGNANS  IDENTIFICATION  ARMATUM  LEAVES  AMIDES  ROOTS  OILS  
Four new species and a new record of Orchidinae (Orchidaceae: Orchideae) from China 期刊论文
PLANT DIVERSITY, 2021, 卷号: 43, 期号: 5, 页码: 390-400
Authors:  Lin,Dong-Liang;  Ya,Ji-Dong;  Schuiteman,Andre;  Ma,Chong-Bo;  Liu,Cheng;  Guo,Xue-Lian;  Chen,Shi-Si;  Wang,Xi-Long;  Zhang,Zhi-Rong;  Yu,Wen-Bin;  Jin,Xiao-Hua
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Orchidaceae  Herminium  Ponerorchis  Peristylus  Platanthera  China  PHYLOGENETIC ANALYSIS  CLASSIFICATION  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
Authors:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
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Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Immunosuppresive Sesterterpenoids and Norsesterterpenoids from Colquhounia coccinea var. mollis 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 16, 页码: 11169-11176
Authors:  Jing,Shu-Xi;  Fu,Ran;  Li,Chun-Huan;  Zhou,Ting-Ting;  Liu,Yan-Chun;  Liu,Yan;  Luo,Shi-Hong;  Li,Xiao-Nian;  Zeng,Fang;  Li,Sheng-Hong
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LEUCOSCEPTRUM-CANUM  GLANDULAR TRICHOMES  PRODUCTS  FAMILY  HARBOR  
Immunosuppressive gentianellane-type sesterterpenoids from the traditional Uighur medicine Gentianella turkestanorum 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 112780
Authors:  Guo,Kai;  Liu,Yan-Chun;  Liu,Yan;  Zhang,Han;  Li,Wen-Yuan;  Shi,Qiu-Mei;  Li,Xiao-Nian;  Zeng,Fang;  Li,Sheng-Hong
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Gentianella turkestanorum  Gentianaceae  Plant sesterterpenoids  Gentianellane-type  Immunosuppressive activity  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  CONSTITUENTS  PRODUCTS  HARBOR  
Immunostimulatory 6/6/6/6 Tetracyclic Triterpenoid Saponins with the Methyl-30 Incorporated Cyclization from the Root of Colquhounia elegans 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7462-7466
Authors:  Hua,Juan;  Liu,Yan-Chun;  Luo,Shi-Hong;  Liu,Yan;  Xiao,Chao-Jiang;  Li,Xiao-Nian;  Li,Sheng-Hong
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QUILLAJA-SAPONARIA  BIOSYNTHESIS  MECHANISMS  ADJUVANTS  VARIANTS  PRODUCTS  CYCLASE