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Neuroprotective compounds from the resinous heartwood of Aquilaria sinensis 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 181, 页码: 112554
Authors:  He,Qian;  Hu,Dong-Bao;  Zhang,Lu;  Xia,Meng-Yuan;  Yan,Hui;  Li,Xiao-Nian;  Luo,Ji-Feng;  Wang,Yun-Song;  Yang,Jing-Hua;  Wang,Yue-Hu
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Aquilaria sinensis  Thymelaeaceae  Sesquiterpenoids  2-(2-Phenylethyl)chromones  Neuroprotective  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
Authors:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
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Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 11, 页码: 7404-7421
Authors:  Zhou,Zongyuan;  Li,Yiming;  Ma,Xiaofang;  Cao,Biyun;  Peng,Ting;  Sheng,Yuwen;  Peng,Huipan;  Li,Runze;  Cao,Yu;  Xi,Ruiying;  Li,Fu;  Wang,Mengru;  Sun,Handong;  Zhang,Guolin;  Zhang,Hongbin;  Hu,Kaifeng;  Xiao,Weilie;  Wang,Fei
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GOMISIN-A  DIBENZOCYCLOOCTADIENE LIGNANS  SCHISANDRA-CHINENSIS  MASS-SPECTROMETRY  MIRNA EXPRESSION  DOWN-REGULATION  NONCODING RNA  MICRORNA  LIVER  DICER  
Prostaglandin E1 Is an Efficient Molecular Tool for Forest Leech Blood Sucking 期刊论文
FRONTIERS IN VETERINARY SCIENCE, 2021, 卷号: 7, 页码: 615915
Authors:  Zheng,Fenshuang;  Zhang,Min;  Yang,Xingwei;  Wu,Feilong;  Wang,Gan;  Feng,Xingxing;  Ombati,Rose;  Zuo,Ruiling;  Yang,Canju;  Liu,Jun;  Lai,Ren;  Luo,Xiaodong;  Long,Chengbo
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leech  blood-sucking  prostaglandin E1  anticoagulant  Haemadipsa sylvestris  MEDICINAL LEECH  PGE1  INFLAMMATION  THERAPY  PAIN  E-1  
A strategy combining solid-phase extraction, multiple mass defect filtering and molecular networking for rapid structural classification and annotation of natural products: characterization of chemical diversity in Citrus aurantium as a case study 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 卷号: 413, 期号: 11, 页码: 2879-2891
Authors:  Wang,Yi-Kun;  Xiao,Xue-Rong;  Zhou,Zi-Meng;  Xiao,Yao;  Zhu,Wei-Feng;  Liu,Hong-Ning;  Li,Fei
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Solid-phase extraction  Multiple mass defect filtering  Molecular networking  Natural products annotation  Structure and substructure classifications  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
Authors:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
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Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
Authors:  Wang,Gan;  Yang,Meng-Li;  Duan,Zi-Lei;  Liu,Feng-Liang;  Jin,Lin;  Long,Cheng-Bo;  Zhang,Min;  Tang,Xiao-Peng;  Xu,Ling;  Li,Ying-Chang;  Kamau,Peter Muiruri;  Yang,Lian;  Liu,Hong-Qi;  Xu,Jing-Wen;  Chen,Jie-Kai;  Zheng,Yong-Tang;  Peng,Xiao-Zhong;  Lai,Ren
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SARS  ENTRY  MERS  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Phyllanthacidoid U: a new N-glycosyl norbisabolane sesquiterpene from Phyllanthus acidus (L.) skeels 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 21, 页码: 3540-3547
Authors:  Xin,Ying;  Xu,Min;  Wang,Ya-Feng;  Zheng,Xiao-Hong;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Phyllanthus acidus  phyllanthacidoid U  norbisabolane sesquiterpenoid  amide  TUSSILAGO-FARFARA  FLOWER BUDS  EXTRACTS  PLANTS  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
Authors:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
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