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Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
Adobe PDF(4739Kb)  |  收藏  |  浏览/下载:167/28  |  提交时间:2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Structural basis of the mechanism of beta-methyl epimerization by enzyme MarH 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 44, 页码: 9605-9614
作者:  Liu, Bin;  Hou, Yan;  Wang, Xiaozheng;  Ma, Xiaofang;  Fang, Shiqi;  Huang, Tao;  Chen, Yanli;  Bai, Zhiqiang;  Lin, Shuangjun;  Zhang, Rundong;  Hu, Kaifeng
Adobe PDF(2826Kb)  |  收藏  |  浏览/下载:149/34  |  提交时间:2020/03/18
A new erythrinan N-oxide alkaloid from Erythrina stricta 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 14, 页码: 2004-2010
作者:  Wu, Jing;  Zhang, Bing-Jie;  Bao, Mei-Fen;  Cai, Xiang-Hai
Adobe PDF(1025Kb)  |  收藏  |  浏览/下载:218/128  |  提交时间:2019/03/25
Erythrina stricta  erythrinan alkaloids  11 beta-hydroxyerythratidine N-oxide  
The sources and mechanisms of bioactive ingredients in coffee 期刊论文
FOOD & FUNCTION, 2019, 卷号: 10, 期号: 6, 页码: 3113-3126
作者:  Hu, G. L.;  Wang, X.;  Zhang, L.;  Qiu, M. H.
Adobe PDF(2231Kb)  |  收藏  |  浏览/下载:169/48  |  提交时间:2019/09/10
Spectroscopic and Molecular Docking Approaches for Investigation of Interaction of Phellopterin with Human Serum Albumin 期刊论文
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2019, 卷号: 47, 期号: 3, 页码: E19027-E19033
作者:  Cao Tuan-Wu;  Tan Xiao-Ping;  Huang Lu-Ping;  Shi Jian-Wei;  Xu Gang
Adobe PDF(1426Kb)  |  收藏  |  浏览/下载:122/20  |  提交时间:2019/07/29
Phellopterin  Human serum albumin  Binding interaction  Fluorescence spectroscopy  Molecular docking  
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
Adobe PDF(2732Kb)  |  收藏  |  浏览/下载:234/42  |  提交时间:2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS  
Protein Aggregation and Performance Optimization Based on Microconformational Changes of Aromatic Hydrophobic Regions 期刊论文
MOLECULAR PHARMACEUTICS, 2018, 卷号: 15, 期号: 6, 页码: 2257-2267
作者:  Wen, Lili;  Lyu, Man;  Xiao, Huashuai;  Lan, Hairong;  Zuo, Zhili;  Yin, Zongning
收藏  |  浏览/下载:112/0  |  提交时间:2018/07/16
Protein Aggregation  Aromatic Hydrophobic Regions  Amine Compounds  Guanidine Compounds  Microconformational Change  
Gene structure, expression pattern and interaction of Nuclear Factor-Y family in castor bean (Ricinus communis) 期刊论文
PLANTA, 2018, 卷号: 247, 期号: 3, 页码: 559-572
作者:  Wang, Yue;  Xu, Wei;  Chen, Zexi;  Han, Bing;  Haque, Mohammad E.;  Liu, Aizhong
Adobe PDF(4009Kb)  |  收藏  |  浏览/下载:230/89  |  提交时间:2018/05/08
Abiotic Stress  Castor Bean  Expression Profiles  Nf-y Transcription Factor  Protein Interaction  
Two New Compounds from Medicinal Insect Blaps japanensis and Their Biological Evaluation 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2018, 卷号: 13, 期号: 2, 页码: 149-151
作者:  Zheng, Tao;  Ming, Yan-Yong;  Tu, Zheng-Chao;  Xu, Fu Rong;  Cheng, Yong-Xian
收藏  |  浏览/下载:81/0  |  提交时间:2018/07/16
Blaps Japanensis  Insect  Pipajiains f And g  Biological Evaluation  
Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
作者:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
Adobe PDF(2083Kb)  |  收藏  |  浏览/下载:160/51  |  提交时间:2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics