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KIB OpenIR
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Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
作者:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin;  Fei, Cong;  Miao, Haofei;  Jing, Changbin;  Ma, Wenjing;  Wang, Lei;  Xie, Sichun;  Li, Chen;  Zeng, Rong;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1157Kb)  |  收藏  |  浏览/下载：613/122  |  提交时间：2013/10/16
Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation  
Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e73527
作者:  Hu, Rongkuan;  Yan, Huan;  Hao, Xiaojiang;  Liu, Haiyang;  Wu, Jiarui
浏览  |  Adobe PDF(1041Kb)  |  收藏  |  浏览/下载：551/75  |  提交时间：2013/10/16
Activated Protein-kinase  Fatty-acid Oxidation  Respiratory Complex-i  Insulin-resistance  Malonyl-coa  Signaling Pathways  Glucose-uptake  L6 Myotubes  Hepg2 Cells  Metformin  
Inhibition of 11 beta-HSD1 by Tetracyclic Triterpenoids from Euphorbia kansui 期刊论文
MOLECULES, 2012, 卷号: 17, 期号: 10, 页码: 11826-11838
作者:  Guo, Jie;  Zhou, Li-Yan;  He, Hong-Ping;  Leng, Ying;  Yang, Zhen;  Hao, Xiao-Jiang
Adobe PDF(1631Kb)  |  收藏  |  浏览/下载：305/59  |  提交时间：2013/01/22
Tetracyclic Triterpenoids  Euphorbia Kansui  Inhibition Of 11 Beta-hsd1  Docking  
A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis 期刊论文
CELL RESEARCH, 2011, 卷号: 21, 期号: 5, 页码: 730-740
作者:  Wang, Wei;  Liu, Haiyang;  Wang, Sheng;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1539Kb)  |  收藏  |  浏览/下载：274/33  |  提交时间：2012/07/25
Wnt  Small Molecule  Inhibitor  Tumorigenesis  
Amide N-glycosylation by Asm25, an N-glycosyltransferase of ansamitocins 期刊论文
CHEMISTRY & BIOLOGY, 2008, 卷号: 15, 期号: 8, 页码: 863-874
作者:  Zhao, Peiji;  Bai, Linquan;  Ma, Juan;  Zeng, Ying;  Li, Lei;  Zhang, Yirong;  Lu, Chunhua;  Dai, Huanqin;  Wu, Zhaoxian;  Li, Yaoyao;  Wu, Xuan;  Chen, Gang;  Hao, Xiaojiang;  Shen, Yuemao;  Deng, Zixin;  Floss, Heinz G.
Adobe PDF(1375Kb)  |  收藏  |  浏览/下载：354/128  |  提交时间：2011/11/24
Biosynthetic Gene-cluster  Lechevalieria-aerocolonigenes Atcc-39243  Escherichia-coli  3-amino-5-hydroxybenzoic Acid  Actinosynnema-pretiosum  Maytansinoid Antibiotics  Streptomyces Sp  Indolocarbazole  Expression  Substrate  
High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 6, 页码: 752-758
作者:  Yan, Jian-hua;  Li, Qun-yi;  Boutin, Jean A.;  Renard, M. Pierre;  Ding, Yi-xiang;  Hao, Xiao-jiang;  Zhao, Wei-min;  Wang, Ming-wei
Adobe PDF(435Kb)  |  收藏  |  浏览/下载：356/105  |  提交时间：2011/12/19
Melanin-concentrating Hormone  Melanin-concentrating Hormone Receptor-1  Antagonist  
Effects of spiramine T on antioxidant enzymatic activities and nitric oxide production in cerebral ischemia-reperfusion gerbils 期刊论文
BRAIN RESEARCH, 2002, 卷号: 944, 期号: 1-2, 页码: 205-209
作者:  Li, L;  Shen, YM;  Yang, XS;  Wu, WL;  Wang, BG;  Chen, ZH;  Hao, XJ
Adobe PDF(294Kb)  |  收藏  |  浏览/下载：292/97  |  提交时间：2012/03/21
Spiraea Japonica Var. Acuta  Rosaceae  Spiramine t  Cerebral Ischemia-reperfusion  Antioxidant Enzyme  Nitric Oxide Synthase