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Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 11, 页码: 3576-3589
Authors:  Li, Xue;  Kong, Lingmei;  Yang, Qihong;  Duan, Aizhu;  Ju, Xiaoman;  Cai, Bicheng;  Chen, Lin;  An, Tao;  Li, Yan
Favorite  |  View/Download:4/0  |  Submit date:2020/06/08
small molecule  deubiquitylation (deubiquitination)  Wnt signaling  pharmacology  enzyme inhibitor  ?-catenin  parthenolide  ubiquitination  USP7  Wnt signaling  ubiquitin-specific peptidase 7  colorectal cancer  proteasome system  protein homeostasis  deubiquitinating activity  
Characterization of a sesquiterpene cyclase from the glandular trichomes of Leucosceptrum canum for sole production of cedrol in Escherichia coli and Nicotiana benthamiana 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 121-128
Authors:  Luo, Fei;  Ling, Yi;  Li, De-Sen;  Tang, Ting;  Liu, Yan-Chun;  Liu, Yan;  Li, Sheng-Hong
View  |  Adobe PDF(2851Kb)  |  Favorite  |  View/Download:52/2  |  Submit date:2019/07/29
Leucosceptrum canum  Lamiaceae  Cedrol  Sesquiterpene cylase  Cedrol synthase  Heterologous production  Synthetic biology  
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
Authors:  Qiu, Jie;  Yuan, Chun-Mao;  Wen, Min;  Li, Ya-Nan;  Chen, Juan;  Jian, Jun-You;  Huang, Lie-Jun;  Gu, Wei;  Li, Yan-Mei;  Hao, Xiao-Jiang
View  |  Adobe PDF(1093Kb)  |  Favorite  |  View/Download:59/3  |  Submit date:2019/07/29
Parthenolide-thiazolidinedione hybrids  click chemistry  cytotoxic activities  
Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2019, 卷号: 36, 期号: 4, 页码: 626-665
Authors:  Liu, Yan;  Jing, Shu-Xi;  Luo, Shi-Hong;  Li, Sheng-Hong
View  |  Adobe PDF(5702Kb)  |  Favorite  |  View/Download:73/13  |  Submit date:2019/05/24
Difengpienols A and B, two new sesqui-neolignans with anti-inflammatory activity from the bark of Illicium difengpi 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 30, 页码: 210-214
Authors:  Pan, Zheng-Hong;  Cheng, Ling;  Ning, De-Sheng;  Peng, Li-Yan;  Fu, Yu-Xia;  Li, Lian-Chun
View  |  Adobe PDF(928Kb)  |  Favorite  |  View/Download:80/2  |  Submit date:2019/04/15
Illicium difengpi  Difengpienol A  Difengpienol B  Sesqui-neolignans  Anti-inflammatory  
Cytotoxic sesquiterpenoids from the leaves of Magnolia grandiflora 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 155, 页码: 182-190
Authors:  Ding, Lin-Fen;  Su, Jia;  Pan, Zheng-Hong;  Zhang, Zhi-Jun;  Li, Xiao-Nian;  Song, Liu-Dong;  Wu, Xing-De;  Zhao, Qin-Shi
View  |  Adobe PDF(1049Kb)  |  Favorite  |  View/Download:393/41  |  Submit date:2018/11/12
Magnolia Grandiflora (Magnoliaceae)  Sesquiterpenoids  Cytotoxic Activity  Nf-kappa b Transcriptional Activity  
12th全国天然有机化学学术会议摘要集 会议录
Editors:  中国化学会
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The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
Authors:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
Favorite  |  View/Download:350/0  |  Submit date:2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Localisation of Two Bioactive Labdane Diterpenoids in the Peltate Glandular Trichomes of Leonurus japonicus by Laser Microdissection Coupled with UPLC-MS/MS 期刊论文
PHYTOCHEMICAL ANALYSIS, 2017, 卷号: 28, 期号: 5, 页码: 404-409
Authors:  Xiao, Chao-Jiang;  Liu, Yan-Chun;  Luo, Shi-Hong;  Hua, Juan;  Liu, Yan;  Li, Sheng-Hong
View  |  Adobe PDF(282Kb)  |  Favorite  |  View/Download:115/27  |  Submit date:2017/10/23
Leonurus Japonicus  Glandular Trichomes  Laser Microdissection  Labdane Diterpenoids  Biological Activities  
四种唇形科植物的次生代谢产物与生物功能研究 学位论文
: 中国科学院大学, 2017
Authors:  肖朝江
Adobe PDF(13791Kb)  |  Favorite  |  View/Download:43/7  |  Submit date:2019/06/14