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Blocking ROR1 enhances the roles of erlotinib in lung adenocarcinoma cell lines 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 3, 页码: 2977-2984
Authors:  Wang, Hui-Li;  Liu, Yan-Chun;  Long, Ming-Peng;  Zheng, Chuan;  Yang, Jia-Hui
Favorite  |  View/Download:4/0  |  Submit date:2019/11/07
receptor tyrosine kinase-like orphan receptor 1  lung adenocarcinoma  erlotinib resistance  AKT  mammalian target of rapamycin  small interfering RNA  
Synthesis and antitumor evaluation of neolaxiflorin B inspired compounds 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 3021-3028
Authors:  Liu, Jing-Ping;  Xiao, Ye-Zhi;  Hu, Yu;  Li, Xiao-Nian;  Wu, Ming-Jiang;  Zhao, Yong;  Zhao, Yan;  Ma, Ze-Jin;  Shen, Jing
Favorite  |  View/Download:5/0  |  Submit date:2019/10/28
neolaxiflorin B inspired compounds  unsaturated ketone  antitumor activity  
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
Authors:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
Favorite  |  View/Download:35/0  |  Submit date:2019/03/18
ent-kaurane-type diterpenoid derivatives  antitumor  synthesis  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
Authors:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Favorite  |  View/Download:115/0  |  Submit date:2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
紫金龙等五种药用植物异喹啉和吲哚结构及生物活性研究 学位论文
: 中国科学院大学, 2017
Authors:  王蓓
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三种天然产物的结构修饰与生物活性研究 学位论文
: 中国科学院大学, 2017
Authors:  任健
Adobe PDF(19285Kb)  |  Favorite  |  View/Download:28/5  |  Submit date:2019/06/14
Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 2, 页码: 2681-2693
Authors:  Cheng, Xin;  Liu, Yong-Qiang;  Wang, Gui-Zhen;  Yang, Li-Na;  Lu, Yong-Zhi;  Li, Xin-Chun;  Zhou, Bo;  Qu, Li-Wei;  Wang, Xiao-Lu;  Cheng, Yong-Xian;  Liu, Jinsong;  Tao, Sheng-Ce;  Zhou, Guang-Biao
View  |  Adobe PDF(7649Kb)  |  Favorite  |  View/Download:76/2  |  Submit date:2017/04/18
Proteome Microarray  6-o-angeloylplenolin  Stat3 Inhibitor  Skp2  Lung Cancer  
Dasyscyphins 类天然产物、(-)-Akaol A 及(±)-Lingzhiol 的合成研究 学位论文
: 中国科学院大学, 2016
Authors:  刘浩淼
Adobe PDF(11426Kb)  |  Favorite  |  View/Download:364/3  |  Submit date:2018/08/23
N-羟基邻苯二甲酰亚胺的抗肿瘤活性及作用机制研究 学位论文
: 中国科学院大学, 2016
Authors:  王敏
Adobe PDF(4685Kb)  |  Favorite  |  View/Download:31/4  |  Submit date:2018/08/23
N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 卷号: 35
Authors:  Wang, Min;  Zhou, Ankun;  An, Tao;  Kong, Lingmei;  Yu, Chunlei;  Liu, Jianmei;  Xia, Chengfeng;  Zhou, Hongyu;  Li, Yan
View  |  Adobe PDF(1734Kb)  |  Favorite  |  View/Download:82/7  |  Submit date:2016/06/27
N-hydroxyphthalimide  Mtor  Inhibitor  Cancer  Mitochondrial Apoptosis