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Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
Authors:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
Favorite  |  View/Download:8/0  |  Submit date:2019/03/18
ent-kaurane-type diterpenoid derivatives  antitumor  synthesis  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
Authors:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Favorite  |  View/Download:105/0  |  Submit date:2018/07/16
Acetyl-macrocalin b  Reactive Oxygen Species  P38 Mapk  Apoptosis  Chk1  Chk2  G2  m Phase Arrest  Nsclc  
紫金龙等五种药用植物异喹啉和吲哚结构及生物活性研究 学位论文
: 中国科学院大学, 2017
Authors:  王蓓
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三种天然产物的结构修饰与生物活性研究 学位论文
: 中国科学院大学, 2017
Authors:  任健
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Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 2, 页码: 2681-2693
Authors:  Cheng, Xin;  Liu, Yong-Qiang;  Wang, Gui-Zhen;  Yang, Li-Na;  Lu, Yong-Zhi;  Li, Xin-Chun;  Zhou, Bo;  Qu, Li-Wei;  Wang, Xiao-Lu;  Cheng, Yong-Xian;  Liu, Jinsong;  Tao, Sheng-Ce;  Zhou, Guang-Biao
View  |  Adobe PDF(7649Kb)  |  Favorite  |  View/Download:71/2  |  Submit date:2017/04/18
Proteome Microarray  6-o-angeloylplenolin  Stat3 Inhibitor  Skp2  Lung Cancer  
Dasyscyphins 类天然产物、(-)-Akaol A 及(±)-Lingzhiol 的合成研究 学位论文
: 中国科学院大学, 2016
Authors:  刘浩淼
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N-羟基邻苯二甲酰亚胺的抗肿瘤活性及作用机制研究 学位论文
: 中国科学院大学, 2016
Authors:  王敏
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N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 卷号: 35
Authors:  Wang, Min;  Zhou, Ankun;  An, Tao;  Kong, Lingmei;  Yu, Chunlei;  Liu, Jianmei;  Xia, Chengfeng;  Zhou, Hongyu;  Li, Yan
View  |  Adobe PDF(1734Kb)  |  Favorite  |  View/Download:76/6  |  Submit date:2016/06/27
N-hydroxyphthalimide  Mtor  Inhibitor  Cancer  Mitochondrial Apoptosis  
Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 33, 页码: 34953-34967
Authors:  Liu,Yong-Qiang;  Wang,Xiao-Lu;  Cheng,Xin;  Lu,Yong-Zhi;  Wang,Gui-Zhen;  Li,Xin-Chun;  Zhang,Jian;  Wen,Zhe-Sheng;  Huang,Zhi-Liang;  Gao,Qin-Lei;  Yang,Li-Na;  Cheng,Yong-Xian;  Tao,Sheng-Ce;  Liu,Jinsong;  Zhou,Guang-Biao
View  |  Adobe PDF(2162Kb)  |  Favorite  |  View/Download:91/11  |  Submit date:2016/01/19
Skp1  Lung Cancer  Structure-based High-throughput Virtual Screening  Inhibitors  6-o-angeloylplenolin  
Targeting cancer with sesterterpenoids: the new potential antitumor drugs 期刊论文
JOURNAL OF NATURAL MEDICINES, 2015, 卷号: 69, 期号: 3, 页码: 255-266
Authors:  Zhang, Caiguo;  Liu, Yan;  Liu,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Photochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  caiguo.zhang@ucdenver.edu;  liuyan@mail.kib.ac.cn
View  |  Adobe PDF(630Kb)  |  Favorite  |  View/Download:68/10  |  Submit date:2015/07/20
Terpenoids  Sesterterpenoids  Cancer Therapy  Structure-activity Relationship