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Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal through inhibition of STAT3 pathway 期刊论文
出版物, 3111, 期号: 0, 页码: 1-50
作者:  Jung Ok Ban;  Dae Hwan Kim;  Hee Pom Lee;  Chul Ju Hwang;  Jung-Hyun Shim;  Dae Joong Kim;  Tae Myoung Kim;  Heon Sang Jeong;  Seong Su Nah;  Hanyong Chen;  Zigang Dong;  Young Wan Ham;  Youngsoo Kim;  Sang-Bae Han;  Jin Tae Hong
Adobe PDF(1327Kb)  |  收藏  |  浏览/下载：342/3  |  提交时间：2017/07/24
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载：369/1  |  提交时间：2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
Pharmacology and anti-addiction effects of the novel kappa opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A 期刊论文
出版物, 3111, 期号: 0, 页码: 1-53
作者:  B Simonson;  A S Morani;  A W M Ewald;  L Walker;  N Kumar;  D Simpson;  J H Miller;  T E Prisinzano;  B M Kivell
Adobe PDF(1394Kb)  |  收藏  |  浏览/下载：495/1  |  提交时间：2017/07/24
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：495/1  |  提交时间：2017/07/24
The dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2-dependent and -independent fever while 4-AA only blocks PGE2-dependent fever1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  David do C. Malvar;  Fernando A. Aguiar;  Artur de L. L. Vaz;  Débora C. R. Assis;  Miriam C. C. de Melo;  Valquíria A. P. Jabor;  Evanguedes Kalapothakis;  Sérgio H. Ferreira;  Giuliano C. Clososki;  Glória E. P. de Souza
Adobe PDF(2243Kb)  |  收藏  |  浏览/下载：476/1  |  提交时间：2017/07/24
Dipyrone  Dipyrone Metabolites  Fever  Hypothermia  Lps  Tityus Serrulatus Venom  
Long-term use of standardised ginkgo biloba extract for theprevention of Alzheimer’s disease (GuidAge): a randomisedplacebo-controlled trial 期刊论文
出版物, 3111, 期号: 0, 页码: 1—9
作者:  Bruno Vellas;  Nicola Coley;  Pierre-Jean Ousset;  Gilles Berrut;  Jean-François Dartigues;  Bruno Dubois;  Hélène Grandjean;  Florence Pasquier;  François Piette;  Philippe Robert;  Jacques Touchon;  Philippe Garnier;  Hélène Mathiex-Fortunet;  Sandrine Andrieu;  for the GuidAge Study Group
Adobe PDF(230Kb)  |  收藏  |  浏览/下载：286/1  |  提交时间：2017/07/21
Effects of CO-RM2 on LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  Pei-Ling Chi;  Yu-Chen Chuang;  Yu-Wen Chen;  Chih-Chung Lin;  Li-Der Hsiao;  Chuen-Mao Yang
Adobe PDF(1319Kb)  |  收藏  |  浏览/下载：323/1  |  提交时间：2017/07/24
Carbon Monoxide  Lipopolysaccharide  Vcam-1  Leukocyte Adhesion  
The protective effect of Allium chinense on anti-cerebral anoxia through regulating NLRP3/NF-?B 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2023, 卷号: 196, 页码: 116499
作者:  Xiao,Xia;  Liu,Yang-Yang;  Yan,Xiao-Jun;  Wang,Xiao-Na;  Hu,Bin-Yuan;  Chen,Song;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Xie,Tian-Zhen;  He,Ying-Jie;  Zhao,Li-Xing;  Zhao,Yun-Li;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2824Kb)  |  收藏  |  浏览/下载：141/16  |  提交时间：2024/07/30
Allium chinense  Cerebral anoxia  Intracellular reactive oxygen species  NLRP3  NF-?B  Nutritional strategy  ACID  MITOCHONDRIA  CONTRIBUTES  METALATION  INHIBITORS  SAPONINS  DAMAGE  
Chemical constituents from the flowers of Hypericum monogynum L. with COX-2 inhibitory activity 期刊论文
PHYTOCHEMISTRY, 2022, 卷号: 193, 页码: 112970
作者:  Li,Ya-Nan;  Zeng,Yan-Rong;  Yang,Jue;  He,Wenwen;  Chen,Junlei;  Deng,Lulu;  Yi,Ping;  Huang,Lie-Jun;  Gu,Wei;  Hu,Zhan-Xing;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
收藏  |  浏览/下载：252/0  |  提交时间：2022/04/02
Hypericum monogynum L.  Hypericaceae  Chemical constituents  Polycyclic polyprenylated acylphloroglucinols  Flavonoids  COX-2 inhibitors  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
作者:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
浏览  |  Adobe PDF(523Kb)  |  收藏  |  浏览/下载：214/39  |  提交时间：2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID