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Efficient Semisynthesis of (-)-Pseudoirroratin A from (-)-Flexicaulin A and Assessment of Their Antitumor Activities 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 3, 页码: 372-376
作者:  Guo, Lei;  Tsang, Siu Wai;  Zhang, Tong-Xin;  Liu, Kang-Lun;  Guan, Yi-Fu;  Wang, Bo;  Sun, Han-Dong;  Zhang, Hong-Jie;  Wong, Man Shing
Adobe PDF(1840Kb)  |  收藏  |  浏览/下载：212/40  |  提交时间：2017/05/19
(-)-pseudoirroratin a  (-)-flexicaulin a  Apoptosis  Antitumor Activity  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：431/205  |  提交时间：2017/02/28
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载：176/29  |  提交时间：2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
Xerophilusin B Induces Cell Cycle Arrest and Apoptosis in Esophageal Squamous Cell Carcinoma Cells and Does Not Cause Toxicity in Nude Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 1, 页码: 10-16
作者:  Yao, Ran;  Chen, Zhaoli;  Zhou, Chengcheng;  Luo, Mei;  Shi, Xuejiao;  Li, Jiagen;  Gao, Yibo;  Zhou, Fang;  Pu, Jianxin;  Sun, Handong;  He, Jie
浏览  |  Adobe PDF(6589Kb)  |  收藏  |  浏览/下载：256/57  |  提交时间：2015/06/29
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：266/68  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Cytotoxic ent-Kaurane Diterpenoids from Isodon wikstroemioides 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 4, 页码: 931-941
作者:  Wu, Hai-Yan;  Zhan, Rui;  Wang, Wei-Guang;  Jiang, Hua-Yi;  Du, Xue;  Li, Xiao-Nian;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(409Kb)  |  收藏  |  浏览/下载：277/60  |  提交时间：2014/06/23
Rubescens Var.-taihangensis  Kaurene Diterpenoids  Maoecrystal-v  C-h  Eriocalyx  Skeleton  
ent-Atisane and ent-kaurane diterpenoids from Isodon rosthornii 期刊论文
FITOTERAPIA, 2013, 卷号: 88, 页码: 76-81
作者:  Zhan, Rui;  Li, Xiao-Nian;  Du, Xue;  Wang, Wei-Guang;  Dong, Ke;  Su, Jia;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(560Kb)  |  收藏  |  浏览/下载：464/48  |  提交时间：2013/10/16
Isorosthornins D-g  Diterpenoids  Isodon Rosthornii  
Bioactive Lignans from the Leaves and Stems of Schisandra wilsoniana 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2013, 卷号: 8, 期号: 4, 页码: 467-470
作者:  Yang, Guang-Yu;  Wang, Rui-Rui;  Gao, Zhong-Hua;  Li, Yin-Ke;  Yang, Liu-Meng;  Li, Xiao-Nian;  Shang, Shan-Zhai;  Zheng, Yong-Tang;  Xiao, Wei-Lie;  Sun, Han-Dong
浏览  |  Adobe PDF(835Kb)  |  收藏  |  浏览/下载：417/148  |  提交时间：2013/06/08
Schisandra Wilsoniana  Lignans  Anti-hiv-1 Activities  Antitumor Activities  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
Adobe PDF(2066Kb)  |  收藏  |  浏览/下载：263/60  |  提交时间：2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53  
Lignans from Kadsura angustifolia and Kadsura coccinea 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2012, 卷号: 14, 期号: 2, 页码: 129-134
作者:  Gao, Xue-Mei;  Pu, Jian-Xin;  Zhao, Yong;  Yang, Li-Bin;  Sun, Han-Dong
浏览  |  Adobe PDF(106Kb)  |  收藏  |  浏览/下载：398/121  |  提交时间：2012/06/07
Kadsura Angustifolia  Kadsura Coccinea  Lignan  Schisandraceae