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(-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 23, 页码: 12859-12867
作者:  Yan,Bing-Chao;  Zhou,Min;  Li,Jian;  Li,Xiao-Nian;  He,Shi-Jun;  Zuo,Jian-Ping;  Sun,Han-Dong;  Li,Ang;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(1930Kb)  |  收藏  |  浏览/下载:64/13  |  提交时间:2022/04/02
bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation  
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
浏览  |  Adobe PDF(3895Kb)  |  收藏  |  浏览/下载:190/47  |  提交时间:2019/12/20
blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载:171/29  |  提交时间:2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载:265/67  |  提交时间:2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Compounds from the Fruits of the Popular European Medicinal Plant Vitex agnus-castus in Chemoprevention via NADP(H):Quinone Oxidoreductase Type 1 Induction 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, 页码: 432829
作者:  Li, Shenghong;  Qiu, Shengxiang;  Yao, Ping;  Sun, Handong;  Fong, Harry H. S.;  Zhang, Hongjie
浏览  |  Adobe PDF(1967Kb)  |  收藏  |  浏览/下载:384/53  |  提交时间:2013/07/24
Constituents  Flavonoids  
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells 期刊论文
NATURE CHEMICAL BIOLOGY, 2012, 卷号: 8, 期号: 5, 页码: 486-493
作者:  Liu, Chuan-Xu;  Yin, Qian-Qian;  Zhou, Hu-Chen;  Wu, Ying-Li;  Pu, Jian-Xin;  Xia, Li;  Liu, Wei;  Huang, Xin;  Jiang, Tao;  Wu, Ming-Xuan;  He, Li-Cai;  Zhao, Ya-Xue;  Wang, Xiao-Lin;  Xiao, Wei-Lie;  Chen, Hong-Zhuan;  Zhao, Qian;  Zhou, Ai-Wu;  Wang, Li-Shun;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(1434Kb)  |  收藏  |  浏览/下载:652/197  |  提交时间:2012/06/07
Cimicifuga Foetida  Cycloartane  Cytotoxicity  Ranunculaceae  Breast-cancer Cells  Crude Drug Shoma  Racemosa Extract  Simplex Wormsk  Cyclolanostanol Xylosides  Triterpene Glycosides  Chemical-constituents  Prostate-cancer  Aerial Parts  Black Cohosh  
Isolation of two bioactive ent-Kauranoids from the leaves of Isodon xerophilus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2007, 卷号: 55, 期号: 15, 页码: 6039-6043
作者:  Weng, Zhi-Ying;  Huang, Sheng-Xiong;  Li, Ma-Lin;  Zeng, Yue-Qin;  Han, Quan-Bin;  Rios, Jose Luis;  Sun, Han-Dong
Adobe PDF(93Kb)  |  收藏  |  浏览/下载:361/120  |  提交时间:2012/10/12
Anti-inflammation  Cytotoxicity  Herbal Tea  Isodon Xerophilus  Ent-kaurene Diterpenoid  
Synthesis and cytotoxicity of some new eriocalyxin B derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 卷号: 42, 期号: 4, 页码: 494-502
作者:  Zhao, Yu;  Niu, Xue-Mei;  Qian, Li-Ping;  Liu, Ze-Yuan;  Zhao, Qin-Shi;  Sun, Han-Dong
Adobe PDF(329Kb)  |  收藏  |  浏览/下载:319/118  |  提交时间:2011/11/24
Eriocalyxin b  Synthesis  Cytotoxicity  Sar  
Eriocalyxin B inhibits nuclear factor-kappa B activation by interfering with the binding of both p65 and p50 to the response element in a noncompetitive manner 期刊论文
MOLECULAR PHARMACOLOGY, 2006, 卷号: 70, 期号: 6, 页码: 1946-1955
作者:  Leung, Chung-Hang;  Grill, Susan P.;  Lam, Wing;  Gao, Wenli;  Sun, Han-Dong;  Cheng, Yung-Chi
浏览  |  Adobe PDF(619Kb)  |  收藏  |  浏览/下载:429/99  |  提交时间:2015/09/23
Effect of total phenolics from Laggera alata on acute and chronic inflammation models 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2006, 卷号: 108, 期号: 2, 页码: 243-250
作者:  Wu, Yihang;  Zhou, Changxin;  Song, Liyan;  Li, Xiangping;  Shi, Shuyun;  Mo, Jianxia;  Chen, Haiyong;  Bai, Hua;  Wu, Xiumei;  Zhao, Jun;  Zhang, Rongping;  Hao, Xiaojiang;  Sun, Handong;  Zhao, Yu
Adobe PDF(343Kb)  |  收藏  |  浏览/下载:367/182  |  提交时间:2011/11/24
Laggera Alata  Folk Medicine  Anti-inflammation  Total Phenolics