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Small compound bigelovin exerts inhibitory effects and triggers proteolysis of E2F1 in multiple myeloma cells 期刊论文
CANCER SCIENCE, 2013, 卷号: 104, 期号: 12, 页码: 1697-1704
作者:  Liu, Jing-Lei;  Zeng, Guang-Zhi;  Liu, Xiao-Li;  Liu, Yong-Qiang;  Hu, Zhong-Guo;  Liu, Ying;  Tan, Ning-Hua;  Zhou, Guang-Biao
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三种药用植物的环肽和其它成分及其活性研究 学位论文
, 北京: 中国科学院大学, 2013
作者:  周文兵
Adobe PDF(8772Kb)  |  收藏  |  浏览/下载：264/10  |  提交时间：2016/05/31
环肽分布  三桠苦  紫菀  毛叶岭南酸枣  吴茱萸属  化学成分  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
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One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
FLORA OF CHINA VOL 2-25 专著
:flora of china 编委会, 2013
作者:  本书编者
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Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 59, 页码: 243-252
作者:  Yue, Grace G. L.;  Chan, Ben C. L.;  Kwok, Hin-Fai;  Wong, Yuk-Lau;  Leung, Hoi-Wing;  Ji, Chang-Jiu;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Tan, Ning-Hua;  Lau, Clara B. S.
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Bigelovin  Inula Helianthus-aquatica  Angiogenesis  Zebrafish  Hmec-1  Cell Adhesion Molecules  
中国生物多样性红色名录高等植物卷 专著
111:内部资料, 2013
作者:  环境保护部和中国科学院
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