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Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：315/74  |  提交时间：2016/06/27
Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 and stimulators of neural stem cell proliferation 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8852-8857
作者:  Tang, Jian-Jun ab;  Zhang, Li;  Jiang, Li-Ping;  Di, Lei;  Yan, Yong-Ming;  Tu, Zheng-Chao;  Yang, Cui-Ping;  Zuo, Zhi-Li;  Hou, Bo;  Xia, Hou-Lin;  Chen, Yong-Bin;  Cheng, Yong-Xian;  Tu,ZC (reprint author),Chinese Acad Sci,Guangzhou Inst Biomed & Hlth,Key Lab Regenerat Biol,Guangzhou 510530,Guangdong,Peoples R China.;  tu_zhengchao@gibh.ac.cn;  ybchen@mail.kiz.ac.cn;  yxcheng@mail.kib.ac.cn
浏览  |  Adobe PDF(678Kb)  |  收藏  |  浏览/下载：464/98  |  提交时间：2015/01/20
Polyrhachis Dives  Dopamine Derivative  Rock1/2 Inhibitors  Nscs  
Aspergillines A-E, Highly Oxygenated Hexacyclic Indole-Tetrahydrofuran-Tetramic Acid Derivatives from Aspergillus versicolor 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 19, 页码: 5016-5019
作者:  Zhou, Min;  Miao, Ming-Ming;  Du, Gang;  Li, Xiao-Nian;  Shang, Shan-Zhai;  Zhao, Wei;  Liu, Zhi-Hua;  Yang, Guang-Yu;  Che, Chun-Tao;  Hu, Qiu-Fen;  Gao, Xue-Mei;  Hu,QF (reprint author),China Tobacco Yunnan Ind Co Ltd,Key Lab Tobacco Chem Yunnan Prov,Kunming 650231,Peoples R China.;  huqiufena@aliyun.com;  gao_xuemei@hotmail.com
Adobe PDF(277Kb)  |  收藏  |  浏览/下载：316/91  |  提交时间：2014/11/25
Cyclopiazonic Acid  Biological-activity  Biosynthesis  Flavus  
Cytotoxic ent-Kaurane Diterpenoids from Isodon wikstroemioides 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 4, 页码: 931-941
作者:  Wu, Hai-Yan;  Zhan, Rui;  Wang, Wei-Guang;  Jiang, Hua-Yi;  Du, Xue;  Li, Xiao-Nian;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(409Kb)  |  收藏  |  浏览/下载：305/67  |  提交时间：2014/06/23
Rubescens Var.-taihangensis  Kaurene Diterpenoids  Maoecrystal-v  C-h  Eriocalyx  Skeleton  
Nortriterpenoids from Schisandra chinensis and their absolute configurational assignments by electronic circular dichroism study 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 4, 页码: 859-868
作者:  Shi, Yi-Ming;  Wang, Li-Yan;  Zou, Xi-Sheng;  Li, Xiao-Nian;  Shang, Shan-Zhai;  Gao, Zhong-Hua;  Liang, Cheng-Qin;  Luo, Huai-Rong;  Li, Hong-Lin;  Xiao, Wei-Lie;  Sun, Han-Dong
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Schisandra  Schisandra Chinensis  Nortriterpenoid  Electronic Circular Dichroism  Absolute Configuration  
(+/-)-Aspongamide A, an N-Acetyldopamine Trimer Isolated from the Insect Aspongopus chinensis, Is an Inhibitor of p-Smad3 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 2, 页码: 532-535
作者:  Yan, Yong-Ming;  Ai, Jun;  Shi, Yan-Ni;  Zuo, Zhi-Li;  Hou, Bo;  Luo, Jie;  Cheng, Yong-Xian
Adobe PDF(229Kb)  |  收藏  |  浏览/下载：443/76  |  提交时间：2014/04/09
Disease  Products  
Lingzhiols, Unprecedented Rotary Door-Shaped Meroterpenoids as Potent and Selective Inhibitors of p-Smad3 from Ganoderma lucidum 期刊论文
ORGANIC LETTERS, 2013, 卷号: 15, 期号: 21, 页码: 5488-5491
作者:  Yan, Yong-Ming;  Ai, Jun;  Zhou, Li-Li;  Chung, Arthur C. K.;  Li, Rong;  Nie, Jing;  Fang, Ping;  Wang, Xin-Long;  Luo, Jie;  Hu, Qun;  Hou, Fan-Fan;  Cheng, Yong-Xian
Adobe PDF(299Kb)  |  收藏  |  浏览/下载：641/133  |  提交时间：2014/01/13
Diabetic-nephropathy  High-glucose  Mesangial Cells  Up-regulation  Expression  Activation  Pathways  
Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 14, 页码: 4218-4224
作者:  Zhu, Jinmei;  Wu, Chun-Feng;  Li, Xiaobing;  Wu, Gui-Sheng;  Xie, Shan;  Hu, Qian-Nan;  Deng, Zixin;  Zhu, Michael X.;  Luo, Huai-Rong;  Hong, Xuechuan
浏览  |  Adobe PDF(1174Kb)  |  收藏  |  浏览/下载：536/90  |  提交时间：2013/10/16
Alzheimer's Disease  Acetylcholinesterase  Butyrylcholinesterase  Molecular Modeling  2-aminobenzimidazole  
Wilsonols A-L, Megastigmane Sesquiterpenoids from the Leaves of Cinnamomum wilsonii 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 7, 页码: 1303-1312
作者:  Shu, Penghua;  Wei, Xialan;  Xue, Yongho;  Li, Weijie;  Zhang, Jinwen;  Xiang, Ming;  Zhang, Mengke;  Luo, Zengwei;  Li, Yan;  Yao, Guangmin;  Zhang, Yonghui
浏览  |  Adobe PDF(469Kb)  |  收藏  |  浏览/下载：293/87  |  提交时间：2013/10/16
Apollonias-barbujana  Subavenium  Cassia  C-13-norisoprenoids  Constituents  Glucosides  Glycosides  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
浏览  |  Adobe PDF(531Kb)  |  收藏  |  浏览/下载：312/66  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol