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Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：126/38  |  提交时间：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
浏览  |  Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：144/61  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2223Kb)  |  收藏  |  浏览/下载：131/53  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY  
Aqueous extract of clove inhibits tumor growth by inducing autophagy through AMPK/ULK pathway 期刊论文
PHYTOTHERAPY RESEARCH, 2019, 卷号: 33, 期号: 7, 页码: 1794-1804
作者:  Li, Cong;  Xu, Huanli;  Chen, Xiaoliang;  Chen, Jijun;  Li, Xiao;  Qiao, Gan;  Tian, Ye;  Yuan, Ru;  Su, Shuonan;  Liu, Xiaohui;  Lin, Xiukun
浏览  |  Adobe PDF(1218Kb)  |  收藏  |  浏览/下载：187/50  |  提交时间：2019/09/10
AMPK  anticancer  aqueous extract of clove  autophagy  traditional Chinese medicine  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
作者:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(3731Kb)  |  收藏  |  浏览/下载：220/49  |  提交时间：2019/06/24
Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Bioinformatics analysis of differentially expressed genes in hepatocellular carcinoma cells exposed to Swertiamarin 期刊论文
JOURNAL OF CANCER, 2019, 卷号: 10, 期号: 26, 页码: 6526-6534
作者:  Tang, Haoran;  Ke, Yang;  Ren, Zongfang;  Lei, Xuefen;  Xiao, Shufeng;  Bao, Tianhao;  Shi, Zhitian;  Zou, Renchao;  Wu, Tiangen;  Zhou, Jian;  Geng, Chang-An;  Wang, Lin;  Chen, Jijun
浏览  |  Adobe PDF(2228Kb)  |  收藏  |  浏览/下载：145/35  |  提交时间：2020/03/24
swertiamarin  microarray  HepG2 cells  hepatocellular cancer  Jun  Stat3  
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 期号: 0, 页码: 381-393
作者:  Yang, Tong-Hua;  Ma, Yun-Bao;  Geng, Chang-An;  Yan, De-Xiu;  Huang, Xiao-Yan;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2088Kb)  |  收藏  |  浏览/下载：236/75  |  提交时间：2018/10/04
Depression  Magnolol Derivatives  Mt1/2 Receptors  Metabolites  Monoamine Neurotransmitter  
Paeoveitols A-E from Paeonia veitchii 期刊论文
FITOTERAPIA, 2015, 卷号: 106, 页码: 36-40
作者:  Liang,Wen-Juan;  Ma,Yun-Bao;  Geng,Chang-An;  Huang,Xiao-Yan;  Xu,Hong-Bo;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(591Kb)  |  收藏  |  浏览/下载：227/60  |  提交时间：2016/01/19
Paeoveitols A-e  Monoterpenes  Benzofurans  Paeonia Veitchii  Paeoniaceae  
The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats 期刊论文
HORMONES AND BEHAVIOR, 2015, 卷号: 69, 期号: 1, 页码: 106-115
作者:  Yu,Dafu;  Zhou,Heng;  Yang,Yuan;  Jiang,Yong;  Wang,Tianchao;  Lv,Liang;  Zhou,Qixin;  Yang,Yuexiong;  Dong,Xuexian;  He,Jianfeng;  Huang,Xiaoyan;  Chen,Jijun;  Wu,Kunhua;  Xu,Lin;  Mao,Rongrong;  Xu,L (reprint author),Chinese Acad Sci,Kunming Inst Zool,Lab Learning & Memory,Kunming 650223,Yunnan,Peoples R China.;  lxu@vip.163.com;  talktomaomao@163.com
浏览  |  Adobe PDF(867Kb)  |  收藏  |  浏览/下载：429/156  |  提交时间：2015/06/29
Hypothyroidism  Hyperthyroidism  Depression  Anxiety  Brain-derived Neurotrophic Factor  
Natural products as antidepressants documented in Chinese patents from 1992 to 2013 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 卷号: 17, 期号: 2, 页码: 188-198
作者:  Sun,Chang-Li;  Geng,Chang-An;  Yin,Xiu-Juan;  Huang,Xiao-Yan;  Chen,Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  chenjj@mail.kib.ac.cn
浏览  |  Adobe PDF(245Kb)  |  收藏  |  浏览/下载：284/81  |  提交时间：2015/06/29
Chinese Patents  Natural Products  Antidepressants