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A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
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Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Functional triterpenoids from medicinal fungi Ganoderma applanatum: A continuous search for antiadipogenic agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104977
作者:  Su,Hai-Guo;  Wang,Qian;  Zhou,Lin;  Peng,Xing-Rong;  Xiong,Wen-Yong;  Qiu,Ming -Hua
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Ganoderma applanatum  Lanostane triterpenoids  Antiadipogenic effects  LANOSTANE-TYPE TRITERPENOIDS  ACID  
The new chimeric chiron genes evolved essential roles in zebrafish embryonic development by regulating NAD(+) levels 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2021, 卷号: 64, 期号: 11, 页码: 1929-1948
作者:  Fang,Chengchi;  Gan,Xiaoni;  Zhang,Chengjun;  He,Shunping
收藏  |  浏览/下载：92/0  |  提交时间：2022/04/02
new chimeric genes  essential function  NAD plus rate-limiting enzyme  coevolution  COLONY-ENHANCING FACTOR  DE-NOVO ORIGINATION  PHYLOGENETIC ANALYSIS  PROTEIN DIVERSITY  RAPID EVOLUTION  DUPLICATE GENES  GENERATION TIME  PATHWAY  YOUNG  NEOFUNCTIONALIZATION  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
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Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Macathiohydantoin L, a Novel Thiohydantoin Bearing a Thioxohexahydroimidazo [1,5-a] Pyridine Moiety from Maca (Lepidium meyenii Walp.) 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 16, 页码: 4934
作者:  Zhang,Ranran;  Liu,Junhong;  Yan,Hui;  Peng,Xingrong;  Zhang,Ling;  Qiu,Minghua
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Lepidium meyenii  thiohydantoins  thioxohexahydroimidazo [1  5-a] pyridine  neuroprotective activities  IMIDAZOLE ALKALOIDS  DERIVATIVES  EXTRACTION  MACAMIDES  HYDANTOIN  ANALOGS  TUBERS