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Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
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Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 106707
作者:  Xu,Shuangyu;  Tang,Yunyan;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Hao,Xiaojiang;  Yuan,Chunmao
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Magnolia grandiflora  Sesquiterpenoids  Isolation and structural modification  Cytotoxic activity  Apoptosis  LACTONES  DERIVATIVES  LEAVES  AGENTS  
Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
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Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN  
Hybrids of β-triketone and monoterpenoids from the peels of Callistemon viminalis 期刊论文
FITOTERAPIA, 2023, 卷号: 166, 页码: 105459
作者:  Meng,Qing-Hong;  Liu,Hui;  Ling,Shan -Shan;  Yan,Huan;  Liu,Hai-Yang
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Callistemon viminalis  Meroterpenoids  Viminalisones A -D  Antibacterial activity  DIELS-ALDER ADDUCTS  ACYLPHLOROGLUCINOL DERIVATIVES  LEAVES  FRUITS  
Clerodane diterpenoids from the Uygur medicine Salvia deserta with immunosuppressive activity 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113823
作者:  Ren,Xue;  Yuan,Xin;  Jiao,Shan-Shan;  He,Xiao-Ping;  Hu,Hong;  Kang,Juan-Juan;  Luo,Shi-Hong;  Liu,Yan;  Guo,Kai;  Li,Sheng-Hong
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Salvia deserta  Lamiaceae  Clerodane diterpenoids  Chemical constituents  ROOTS  
A new sesquiterpene synthase catalyzing the formation of (R)-fi-bisabolene from medicinal plant Colquhounia coccinea var. mollis and its anti-adipogenic and antibacterial activities 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 211, 页码: 113681
作者:  Li,De-Sen;  Shi,Lin-Lin;  Guo,Kai;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Liu,Yan;  Li,Sheng-Hong
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Sesquiterpenoids  Sesquiterpene synthases  (R)-fi-bisabolene  Colquhounia coccinea var  mollis  Anti-adipogenic activity  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  FUNCTIONAL EXPRESSION  BETA-BISABOLENE  ESSENTIAL OILS  BIOSYNTHESIS  IDENTIFICATION  CYTOTOXICITY  CLONING  
Four new phenolic constituents from the roots of Rumex dentatus L. 期刊论文
FITOTERAPIA, 2023, 卷号: 170, 页码: 105657
作者:  Li,Jing-Juan;  Zhu,Hong-Tao;  Eshbakova,Komila Alibekovna;  Zhang,Man;  Wang,Dong;  Zhang,Ying-Jun
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Rumex dentatus  Polygonaceae  Antifungal activity  Naphthalenes  ANTHRAQUINONE  DERIVATIVES  NAPHTHALENE  
Artemeriosides A-F, the first examples of natural sesquiterpenoids substituted by a 6′-O-crontonyl β-glucopyranoside from Artemisia annua 期刊论文
FITOTERAPIA, 2023, 卷号: 169, 页码: 105619
作者:  He,Xiao-Feng;  Wang,Meng-Fei;  Ma,Yun-Bao;  Li,Tian-Ze;  Chen,Ji-Jun
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Artemisia annua L.  Artemeriosides A-F  Sesquiterpenoids substituted by 6'-O-crontonyl  beta-glucopyranoside  Antihepatoma activity  GENUS  
Two new triterpenoids from the stems of Euphorbia royleana 期刊论文
NATURAL PRODUCT RESEARCH, 2023
作者:  Liu,Wen-Xing;  Zhang,Man;  Zhang,Ying-Jun;  Zhao,Ping
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Euphorbia royleana  triterpenoids  2D NMR  DITERPENES  LATEX  
Modular Synthesis of a Tridecasaccharide Motif of Bacteroides vulgatus Lipopolysaccharides against Inflammatory Bowel Diseases through an Orthogonal One-Pot Glycosylation Strategy 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
作者:  Zhang,Yunqin;  Wang,Leilei;  Zhou,Qingli;  Li,Zuoshan;  Li,Dan;  Yin,Caixia;  Wang,Xiufang;  Xiao,Guozhi
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Anti-Inflammatory Activity  Lipopolysaccharides  Oligosaccharide Synthesis  Orthogonal One-Pot Glycosylation  Stereoselectivity  STEREOSELECTIVE-SYNTHESIS  CHEMICAL-SYNTHESIS  ACID  DONORS  ALKYNYLBENZOATES  GLYCOSIDES  DISCOVERY  CATALYSIS  GLYCANS  FOCUS