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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载:200/41  |  提交时间:2020/03/26
Four new monoterpenoids from the whole plants of Valeriana stenoptera 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 9, 页码: 842-850
作者:  Dong, Fa-Wu;  Yang, Liu;  Zi, Chen-Ting;  Li, Bao-Jing;  Li, Hui-Yuan;  Li, Wen-Jie;  Yang, Yu-Lin;  Hu, Jiang-Miao;  He, Hong-Ping
浏览  |  Adobe PDF(1279Kb)  |  收藏  |  浏览/下载:165/62  |  提交时间:2019/09/10
Valerianaceae  Valeriana stenoptera  acyclic monoterpenoids  iridoids  triterpenoids  
Synthesis and Cytotoxicities of Novel Podophyllotoxin Xyloside Derivatives 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 7, 页码: 6
作者:  Zi, Cheng-Ting;  Yang, Liu;  Zhang, Bang-Lei;  Li, Yan;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao;  Zhou, Jun
浏览  |  Adobe PDF(352Kb)  |  收藏  |  浏览/下载:163/34  |  提交时间:2019/09/10
podophyllotoxin  butyrylated xyloside  cytotoxicity  synthesis  
Rapid discovery and functional characterization of diterpene synthases from basidiomycete fungi by genome mining 期刊论文
FUNGAL GENETICS AND BIOLOGY, 2019, 卷号: 128, 页码: 36-42
作者:  Li, Xin-Lin;  Xu, Yu-Xing;  Li, Yuan;  Zhang, Rui;  Hu, Tian-Yuan;  Su, Ping;  Zhou, Man;  Tang, Ting;  Zeng, Ying;  Yang, Yan-Long;  Gao, Wei
浏览  |  Adobe PDF(1544Kb)  |  收藏  |  浏览/下载:238/40  |  提交时间:2019/07/29
Basidiomycete  Ditepene synthase  Genome mining  Cembrane diterpene  (-)-cyatha-3,12-diene  Ent-kauran-16 alpha-ol  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3915Kb)  |  收藏  |  浏览/下载:225/40  |  提交时间:2019/07/29
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:254/59  |  提交时间:2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Characterization of a sesquiterpene cyclase from the glandular trichomes of Leucosceptrum canum for sole production of cedrol in Escherichia coli and Nicotiana benthamiana 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 121-128
作者:  Luo, Fei;  Ling, Yi;  Li, De-Sen;  Tang, Ting;  Liu, Yan-Chun;  Liu, Yan;  Li, Sheng-Hong
浏览  |  Adobe PDF(2851Kb)  |  收藏  |  浏览/下载:207/36  |  提交时间:2019/07/29
Leucosceptrum canum  Lamiaceae  Cedrol  Sesquiterpene cylase  Cedrol synthase  Heterologous production  Synthetic biology  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
作者:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
浏览  |  Adobe PDF(4316Kb)  |  收藏  |  浏览/下载:222/40  |  提交时间:2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
作者:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(5774Kb)  |  收藏  |  浏览/下载:302/63  |  提交时间:2019/04/15
celastrol  lipidomics  hyperlipidemia  LC-MS  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(500Kb)  |  收藏  |  浏览/下载:429/190  |  提交时间:2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)