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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：396/45  |  提交时间：2017/12/18
老药新用：奥柳氮钠的降尿酸作用及分子机制研究 学位论文
: 中国科学院大学, 2017
作者:  牛艳芬
Adobe PDF(4338Kb)  |  收藏  |  浏览/下载：121/6  |  提交时间：2019/06/14
钯催化非活泼碳氢键胺化反应构建氮杂环骨架的方法学研究 学位论文
: 中国科学院大学, 2017
作者:  赵杰
Adobe PDF(10881Kb)  |  收藏  |  浏览/下载：165/2  |  提交时间：2019/06/14
Virtual screening of B-Raf kinase inhibitors: A combination of pharmacophore modelling, molecular docking, 3D-QSAR model and binding free energy calculation studies 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 70, 页码: 186-190
作者:  Zhang, Wen;  Qiu, Kai-Xiong;  Yu, Fang;  Xie, Xiao-Guang;  Zhang, Shu-Qun;  Chen, Ya-Juan;  Xie, Hui-Ding
浏览  |  Adobe PDF(371Kb)  |  收藏  |  浏览/下载：156/29  |  提交时间：2017/12/11
B-raf Kinase Inhibitors  Virtual Screening  Pharmacophore  Molecular Docking  3d Qsar  Binding Free Energy Calculation  
Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 9, 页码: 1498
作者:  Chen, Huan;  Zhang, Rong;  Luo, Rong-Hua;  Yang, Liu-Meng;  Wang, Rui-Rui;  Hao, Xiao-Jiang;  Zheng, Yong-Tang
浏览  |  Adobe PDF(1939Kb)  |  收藏  |  浏览/下载：218/44  |  提交时间：2017/10/23
Antiviral Agent  12-o-tricosanoylphorbol-20-acetate  Hiv  Vif  Apobec3g  Phorbol Ester  
PPAR alpha activation protects against cholestatic liver injury 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
作者:  Zhao, Qi;  Yang, Rui;  Wang, Jing;  Hu, Dan-Dan;  Li, Fei
浏览  |  Adobe PDF(7693Kb)  |  收藏  |  浏览/下载：253/62  |  提交时间：2017/10/23
Primary Biliary-cirrhosis  Bile-acid Homeostasis  Receptor-alpha  Ursodeoxycholic Acid  Cholesterol 7-alpha-hydroxylase  Beta-oxidation  Fenofibrate  Therapy  Mice  Hepatotoxicity  
ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus 期刊论文
OPEN BIOLOGY, 2017, 卷号: 7, 期号: 8, 页码: 170122
作者:  Ma, Pengcheng;  Ren, Biyu;  Yang, Xiangcai;  Sun, Bin;  Liu, Xiaoliang;  Kong, Qinghua;  Li, Chaocui;  Mao, Bingyu
浏览  |  Adobe PDF(1985Kb)  |  收藏  |  浏览/下载：186/48  |  提交时间：2017/10/23
Zc4h2  Smad  Smurf  Bone Morphogenesis Protein Signalling  Neural Development  
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
Adobe PDF(854Kb)  |  收藏  |  浏览/下载：366/76  |  提交时间：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 11, 页码: 4680-4692
作者:  Qu, Chunrong;  Ding, Mingmin;  Zhu, Yingmin;  Lu, Yungang;  Du, Juan;  Miller, Melissa;  Tian, Jinbin;  Zhu, Jinmei;  Xui, Jian;  Wen, Meng;  Er-Bu, Aga;  Wan, Jule;  Xiao, Yuling;  Wu, Meng;  McManus, Owen B.;  Li, Min;  Wu, Jilin;  Luo, Huai-Rong;  Cao, Zhengyu;  Shen, Bing;  Wang, Hongbo;  Zhu, Michael X.;  Hong, Xuechuan
Adobe PDF(1969Kb)  |  收藏  |  浏览/下载：221/79  |  提交时间：2017/08/29
Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production 期刊论文
MOLECULAR CARCINOGENESIS, 2017, 卷号: 56, 期号: 5, 页码: 1414-1426
作者:  Yu, Xinfang;  Li, Wei;  Deng, Qipan;  You, Shuo;  Liu, Haidan;  Peng, Songling;  Liu, Xiaolan;  Lu, Jingchen;  Luo, Xiangjian;  Yang, Lifang;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Liu, Wenbin;  Wu, Shengqi;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
Adobe PDF(6365Kb)  |  收藏  |  浏览/下载：366/117  |  提交时间：2017/06/30
Angiogenesis  Breast Cancer  Egfr  Neoalbaconol  Vegf